본문 바로가기
KERD
논문KCI 등재

복합운동 수행이 비만청소년의 혈중 C-reactive protein, Interleukin-6, 혈중 지질 및 인슐린 저항성에 미치는 영향

Effects of Combined Aerobic and Resistance Exercise on Plasma C-reactive Protein, Interleukin-6, Lipids, and Insulin Resistance in Obese Adolescent

문희원|신영오|김정규
국민체육진흥공단 한국스포츠과학원 (Korea Institute of Sport Science)|2007.06|체육과학연구 (Korean Journal of Sport Science)|제18권 제2호|pp. 1-9|DOI 10.24985/kjss.2007.18.2.1

1

조회

0

다운로드

26

인용

0

참고문헌

키워드

C-reactive protein혈중 지질복합운동lipids비만청소년C-reactive protein(CRP)interleukin-6(IL-6)인슐린 저항성(HOMA-IR)obese adolescentcombined aerobic and resistance exerciseinterleukin-6insulin resistance WeggeJ.K.RobertsC.K.NgoT.H.& BarnardR.J.(2004). Effect of diet and exercise intervention on inflammatory and adhe
주제분류체육

초록

본 연구에서는 비만청소년을 대상으로 저항성운동과 유산소운동을 병행한 복합운동을 수행하는 것이 혈중 IL-6, CRP, 지질 수준 및 인슐린 저항성 에 미치는 영향을 알아보았다. 연구 대상은 체지방률 30% 이상의 비만청소년이었고 복합운동은 저항성운동(60% 1RM)과 유산소운동(60% HRR)으로 구성하였으며 주 4회 8주 동안 수행하도록 하였다. 연구 결과, 8주 동안의 복합운동 수행은 비만으로 증가되었던 체중, BMI, 체지방률과 체중에 대한 제지방량의 비율을 유의하게 감소시켰다. 혈중 지질성분인 TC, TG, LDL-C, HDL-C 수치는 복합운동 수행 후 유의하게 변화되지 않았으나 대조군에 비해 유의하게 높았던 혈중 인슐린 수치와 HOMA-IR 수치는 유의하게 감소하였다. 혈중 IL-6와 CRP의 경우, 대조군에 비해 비만청소년에서 유의하게 증가되어 있었으나 복합운동 수행 후 유의하게 감소된 것을 확인하였다. 결론적으로, 비만청소년을 대상으로 저항성운동과 유산소운동을 병행한 복합운동을 수행하는 것은 체지방률과 인슐린 저항성을 낮출 뿐만 아니라 비만으로 인한 전신적 염증반응을 유의하게 억제하는 것을 혈중 IL-6와 CRP가 감소된 것으로 알 수 있었다.

Abstract

The purpose of this study is to assess the effects of combined aerobic and resistance exercise (aerobic exercise at 60% HRR, resistance exercise at 60% 1RM) on plasma C reactive-protein (CRP), interleukin-6 (IL-6), lipids, and insulin resistance (HOMA-IR) in obese adolescent. Exercise program was performed for 8 weeks. Body composition and blood biochemical variables were analyzed before and after exercise training. In the results, there were significant differences between obese adolescent group and age-matched control group. Body weight, %fat, BMI, plasma insulin, HOMA-IR, CRP, and IL-6 in obese adolescent were increased significantly than in control group. However, these variables including plasma CRP, IL-6, and HOMA-IR in obese adolescent were decreased significantly after exercise. In conclusion, combined aerobic and resistance exercise program in obese adolescent appears to be helpful for improving the obesity and lowering obese-induced systemic inflammation.

참고문헌 (45)

  1. 김효정, "1년간의 운동 트레이닝이 중년 남성의 심혈관계 질환 위험 지표와 유산소성 운동 능력 및 공복 혈당 장애 개선에 미치는 영향", 14(2), pp.203~214 (2005)
  2. 이동수, "12주간의 유산소운동과 웨이트 트레이닝의 병행이 비만 아동의 혈중지질성분의 변화에 미치는 영향", 12(2), pp.233~242 (2003)
  3. 신윤아, "복합트레이닝 프로그램이 비만인의 렙틴, 아디포넥틴 농도와 대사증후군 요인에 미치는 영향", 14(4), pp.569~582 (2005)
  4. Ahima, R.S, "Adipose tissue as an endocrine organ", 11(8), pp.327~332 (2000)
  5. Banks, R.E, "The acute phase protein response in patients receiving subcutaneous IL-6", 102(1), pp.217~223 (1995)
  6. Bastard, J.P, "Elevated levels of interleukin 6 are reduced in serum and subcutaneous adipose tissue of obese women after weight loss", 85(9), pp.3338~3342 (2000)
  7. Blackburn, ". Validity of acute phase proteins as markers of disease activity. J Rheumatol Suppl", pp.9~13 (1994)
  8. M, ". Rehabilitation in sports medicine. Stanford. Connecticut: Appleton and lange." (1993)
  9. Crichton, M.B, "Expression of transcripts of interleukin-6 and related cytokines by human breast tumors, breast cancer cells, and adipose stromal cells", 118(1-2), pp.215~220 (1996)
  10. Dekker, M.J, "An exercise intervention without weight loss decreases circulating interleukin-6 in lean and obese men with and without type 2 diabetes mellitus", 56(3), pp.332~338 (2007)
  11. Dietz, ". Critical periods in childhood for the development of obesity. Am J Clin Nutr", pp.955~969 (1994)
  12. DuRant, ". Association among serum lipid and lipoprotein concentrations and physical activity and body composition in young children. J Pediatr"
  13. Esposito, K, "Effect of weight loss and lifestyle changes on vascular inflammatory markers in obese women: a randomized trial", 289(14), pp.1799~1804 (2003)
  14. Freedman, ". Relation of body fat patterning to lipid and lipoprotein concentrations in children and adolescents: the Bogalusa Heart Study. Am J Clin Nutr", pp.930~939 (1989)
  15. Goldhammer, E, "Exercise training modulates cytokines activity in coronary heart disease patients", 100(1), pp.93~99 (2005)
  16. "Exercise, glucose transport, and insulin sensitivity", 49, pp.235~261 (1998)
  17. "Associations of C-reactive protein with measures of obesity, insulin resistance, and subclinical atherosclerosis in healthy, middle-aged women", 19(8), pp.1986~1991 (1999)
  18. ". Elevated blood pressure in obese children: influence of gender", pp.453~459 (1991)
  19. ". Obesity as an independent risk factor for cardiovascular disease: a 26-year follow-up of participants in the Framingham Heart Study. Circulation", pp.968~977 (1983)
  20. "Effects of lifestyle modifications on C-reactive protein: contribution of weight loss and improved aerobic capacity", 55(6), pp.825~831 (2006)
  21. ". The effects of training on heart rate", pp.307~15 (1957)
  22. "Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans", 85(7), pp.2402~2410 (2000)
  23. "Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance", 280(5), pp.E745~E751 (2001)
  24. "Exercise as hypertension therapy", 19(3), pp.507~516 (2001)
  25. "Effect of exercise on circulating adipokine levels in obese young women", 53(2), pp.189~195 (2006)
  26. ". Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia", pp.412~419 (1985)
  27. "Differentiation between obesity and insulin resistance in the association with C-reactive protein", 106(23), pp.2908~2912 (2002)
  28. "C reactive protein and its relation to cardiovascular risk factors: a population based cross sectional study", 1312(7038), pp.1061~1065 (1996)
  29. "Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-alpha, in vivo", 82(12), pp.4196~4200 (1997)
  30. "Obesity and high-density lipoprotein cholesterol in black and white 9- and 10-year-old girls: The National Heart, Lung, and Blood Institute Growth and Health Study", 45(4), pp.469~474 (1996)
  31. ". Long-term morbidity and mortality of overweight adolescents. A follow-up of the Harvard Growth Study of 1922 to 1935. N Engl J Med", pp.1350~1355 (1992)
  32. "Aerobic exercise training improves insulin sensitivity without changes in body weight, body fat, adiponectin, and inflammatory markers in overweight and obese girls", 54(11), pp.1472~1479 (2005)
  33. "The pathophysiologic roles of interleukin-6 in human disease", 128(2), pp.127~137 (1998)
  34. "NIDDM as a disease of the innate immune system: association of acute-phase reactants and interleukin-6 with metabolic syndrome X", 40(11), pp.1286~1292 (1997)
  35. "Aromatase activity and interleukin-6 production by normal and malignant breast tissues", 80(10), pp.3052~3058 (1995)
  36. Ryan, A.S, "Reductions in plasma cytokine levels with weight loss improve insulin sensitivity in overweight and obese postmenopausal women", 27(7), pp.1699~1705 (2004)
  37. Shephard, R.J, "Absolute versus relative intensity of physical activity in a dose-response context", 33, pp.S400~S420 (2001)
  38. Shin, Y.O, "Effect of Cardiac Rehabilitation and Statin Treatment on Anti-HSP Antibody Titers in Patients With Coronary Artery Disease After Percutaneous Coronary Intervention", 47(5), pp.671~682 (2006)
  39. Thompson, P.D, "American Heart Association Council on Clinical Cardiology Subcommittee on Exercise, Rehabilitation, and Prevention; American Heart Association Council on Nutrition, Physical Activity, and Metabolism Subcommittee on Physical Activity. Exercise and physical activity in the prevention and treatment of atherosclerotic cardiovascular disease: a statement from the Council on Clinical Cardiology (Subcommittee on Exercise, Rehabilitation, and Prevention) and the Council on Nutrition, Physical Activity, and Metabolism (Subcommittee on Physical Activity)", 107(24), pp.3109~3116 (2003)
  40. Tracy, R.P, "Lifetime smoking exposure affects the association of C-reactive protein with cardiovascular disease risk factors and subclinical disease in healthy elderly subjects", 17(10), pp.2167~2176 (1997)
  41. Visser, M, "Low-grade systemic inflammation in overweight children", 107(1), pp.E13~ (2001)
  42. Visser, M, "Elevated C-reactive protein levels in overweight and obese adults", 282(22), pp.2131~215 (1999)
  43. Wegge, J.K, "Effect of diet and exercise intervention on inflammatory and adhesion molecules in postmenopausal women on hormone replacement therapy and at risk for coronary artery disease", 53(3), pp.377~381 (2004)
  44. You, T, "Effects of hypocaloric diet and exercise training on inflammation and adipocyte lipolysis in obese postmenopausal women", 89(4), pp.1739~1746 (2004)
  45. You, T, "Abdominal adipose tissue cytokine gene expression: relationship to obesity and metabolic risk factors", 288(4), pp.E741~E747 (2005)

관련 논문AI추천

걷기운동과 복합운동이 비만 청소년의 신체조성과 심혈관계 질환 관련 Cytokine에 미치는 영향강희성, 김선희, 김종식, 황은아한국운동생리학회 · 운동과학2012 · 제21권 제1호운동프로그램 형태에 따른 비만여고생의 인슐린저항성, 염증유발지표 및 Leptin의 변화고성경, 김윤미, 성봉주, 정소봉, 천금석국민체육진흥공단 한국스포츠과학원 · 체육과학연구2011 · 제22권 제2호12주간 유산소 운동이 비만 청소년의 비만 지표, 인슐린저항성, 심혈관질환 위험인자 및 운동능력에 미치는 영향강설중, 정성림한국운동생리학회 · 운동과학2010 · 제19권 제3호청소년에서 인슐린저항성, 아디포사이토카인, 심폐체력 및 운동 후 심박수 회복과의 연관성강설중, 정소봉대한운동학회 · 아시아 운동학 학술지2012 · 제14권 제2호12주간 복합운동이 비만 청소년의 체지방 관련 사이토카인에 미치는 영향강희성, 김종식, 조현철한국운동생리학회 · 운동과학2011 · 제20권 제3호12주간 저항성 밴드운동이 비만 청소년의혈중지질 및 염증지표에 미치는 영향신원태, 이수운한국운동생리학회 · 운동과학2012 · 제21권 제4호

이 간행물의 다른 논문 (11건)

신발의 착화시 인지적 편안함과 관련된 요인 분석이충일, 목승한, 전민주, 양정수, 곽창수pp. 10-21지역주민의 라이프스타일에 따른 제주유나이티드 축구단의 시장세분화전략강준호, 김기탁pp. 22-31스포츠산업경영 인력양성 교과과정에 대한 교육자와 현장실무자간의 중요도 인식차이 연구이정학, 방지선pp. 32-39방송사별 해설자의 공신력이 청소년의 TV시청 만족과재시청의도에 미치는 영향-2006 FIFA독일월드컵 중계방송 중심으로-김종훈, 이정학, 노재헌pp. 40-48상업스포츠센터 지도자의 서비스행동이 고객 충성도에 미치는 영향이계석, 김용만pp. 49-61
원문 보기