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전립선암과 양성 전립선 비대증을 위한 운동 치료적 전략

A review of therapeutic exercise strategies for prostate cancer and benign prostate hyperplasia

윤진환
국민체육진흥공단 한국스포츠과학원 (Korea Institute of Sport Science)|2020.03|체육과학연구 (Korean Journal of Sport Science)|제31권 제1호|pp. 1-10|DOI 10.24985/kjss.2020.31.1.1

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참고문헌

키워드

운동Exercise전립선암Prostate cancerBenign prostate hyperplasia양성 전립선 비대증전립선 문제Prostate problems
주제분류체육

초록

[목적] 전립선암과 양성 전립선 비대증 같은 전립선 문제는 안드로겐 및 유전적 요인과 주로 관련된 문제로 인식되어 왔는데, 이러한 문제는 노인들에게 많은 영향을 미쳐 이환율과 사망률에 크게 기여한다. 전립선암과 그와 관련된 치료법은 심혈관 및 성기능 장애와 같은 중요하고 지속적인 이환율을 유발할 수 있는데, 이러한 기능 장애를 예방하거나 완화시키기 위해 다양한 중재가 시도되었다, 본 연구의 목적은 전립선암과 양성 전립선 비대증을 위한 운동 치료적 전략을 도출하기 위하여 MEDLINE, PubMed와 Scopus 등재된 자료와 이전의 문헌들을 고찰하였다, [방법] 이 리뷰는 전립선암과 양성 전립선 비대증 환자를 위한 운동의 치료적 전략을 위하여 문헌 고찰하였다. [결과] 전립선암과 양성 전립선 비대증 환자에 있어서 규칙적인 운동과 함께 금연, 적정 체중 유지 등 몇몇 생활습관을 개선하면 공격적인 암의 발병율의 위험을 감소시킬 수 있을 것이다. [결론] 본 연구의 결과는 신체적 운동 훈련은 전립선 암세포 사멸의 마커를 증가시켜 운동이 전립선암 및 양성 전립선 비대증 치료를 위한 잠재적인 치료 전략으로 제시 될 수 있을 것이다. 미래의 연구들에서는 다양한 전립선암 및 양성 전립선 비대증 환자에 있어서 적정한 운동 기간, 운동 강도, 운동 빈도를 고려한 연구들이 요구된다.

Abstract

[Purpose] Prostate problems, such as prostate cancer, and benign prostate hyperplasia have been recognized as problems largely related to androgens and genetic factors. They affect a large fraction of the elderly population, contributing significantly to morbidity and mortality. Therefore, the purpose of this review paper was to investigate a therapeutic strategies for prostate cancer and benign prostate hyperplasia. [Methods] In order to determine the therapeutic exercise strategies for prostate cancer and benign prostate hyperplasia, previous literature was reviewed with MEDLINE, PubMed, and Scopus databases. [Results] Prostate cancer and its associated treatments can cause significant and lasting morbidities, such as cardiovascular and sexual dysfunctions. Various interventions have attempted to prevent or mitigate these dysfunctions. This review summarizes the available evidence concerning the effects of exercise training on male sexual health in the cancer prevalent population. Smoking cessation, regular exercise, and maintaining healthy weight are important public health targets for intervention. Importantly, several lifestyle modifications may lower the risk of developing more aggressive cancer or offer survival benefits to prostate cancer patients. [Conclusions] In this review article, physical exercise training can increase apoptosis markers in the prostate, suggesting exercise training as a potential novel therapeutic strategies for treating prostate cancer and benign prostate hyperplasia. Future studies in more advanced and varied prostate cancer populations are required to ascertain the duration, intensity and frequency of exercise that optimizes the effects of exercise training on prostate cancer and benign prostate hyperplasia.

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