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화장품 소재로서 강황 추출물과 커큐민의 생리활성 특성 연구

Study on the Bioactive Characteristics of Curcuma longa extract and Curcumin as a Cosmatic Raw Material

최태부|정은진
한국피부과학연구원 (Korea Institute of Dermatological Sciences)|2014.06|아시안뷰티화장품학술지 (Asian Journal of Beauty and Cosmetology)|제12권 제3호|pp. 425-433

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참고문헌

키워드

Anti-inflammationCurcuminCurcuma longa extractAnti-melaninanti-oxidation
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초록

The bioactive characteristics of curcumin, the main ingredient of Curcuma longa and Curcuma longa extract wasstudied to use as a cosmetic ingredient. The bioactive characteristics of cosmetic ingredients of this study include antimicrobialactivity, anti-oxidation activity, anti-inflammation activity, whitening effect. The anti-oxidation activity has foundthat curcumin has the radical scavenging ability and polyphenol with high anti-oxidative activity. The anti-bacterialeffect of curcumin and Curcuma longa extract has found to show the comparatively lower anti-bacterial effect in the5 strains including S.aureus, E.coli, P.aeruginosa, C.albicans, and M. furfur. The anti-inflammatory effect of curcuminhas found that the inhibition concentration, IC50 of NO production was as low as 6 μM. The anti-melanin effect ofcurcumin has found that about 60% of melanogenesis was inhibited at 20 μM of curcumin concentration by usingB16F10 cell when compared to that of the control group. In conclusion, Curcuma longa extract cannot be use as acosmetic material, curcumin can be used as the functional cosmetics material in the future as it has found to have theweak anti-oxidant and anti-bacterial effects and strong anti- inflammatory and anti-melanin efects.

Abstract

The bioactive characteristics of curcumin, the main ingredient of Curcuma longa and Curcuma longa extract wasstudied to use as a cosmetic ingredient. The bioactive characteristics of cosmetic ingredients of this study include antimicrobialactivity, anti-oxidation activity, anti-inflammation activity, whitening effect. The anti-oxidation activity has foundthat curcumin has the radical scavenging ability and polyphenol with high anti-oxidative activity. The anti-bacterialeffect of curcumin and Curcuma longa extract has found to show the comparatively lower anti-bacterial effect in the5 strains including S.aureus, E.coli, P.aeruginosa, C.albicans, and M. furfur. The anti-inflammatory effect of curcuminhas found that the inhibition concentration, IC50 of NO production was as low as 6 μM. The anti-melanin effect ofcurcumin has found that about 60% of melanogenesis was inhibited at 20 μM of curcumin concentration by usingB16F10 cell when compared to that of the control group. In conclusion, Curcuma longa extract cannot be use as acosmetic material, curcumin can be used as the functional cosmetics material in the future as it has found to have theweak anti-oxidant and anti-bacterial effects and strong anti- inflammatory and anti-melanin efects.

참고문헌 (44)

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