반구형 플라스틱 구조체 성형을 위한 프리폼 몰드 사출성형공정 최적화
Optimization of preform mold injection molding process for hemispheric plastic structure fabrication
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Traditional cell culture(2-dimensional) is the method that provide a nutrient and environment on a flat surface to cultivate cells into a single layer. Since the cell characteristics of 2D culture method is different from the characteristics of the cells cultured in the body, attempts to cultivate the cells in an environment similar to the body environment are actively proceeding in the industry, academy, and research institutes. In this study, we will develop a technology to fabricate micro-structures capable of culturing cells on surfaces with various curvatures, surface shapes, and characteristics. In order to fabricate the hemispheric plastic structure(thickness 50 ㎛), plastic preform mold (hereinafter as "preform mold") corresponding to the hemisphere was first prepared by injection molding in order to fabricate a two - layer structure to be combined with a flat plastic film. Then, thermoplastic polymer dissolved in an organic solvent was solidified on a preform mold. As a preliminary study, we proposed injection molding conditions that can minimize X/Y/Z axis deflection value. The effects of the following conditions on the preform mold were analyzed through injection molding CAE, [(1) coolant inlet temperature, (2) injection time, (3) packing pressure, (4) volume-pressure (V/P). As a result, the injection molding process conditions (cooling water inlet temperature, injection time, holding pressure condition (V / P conversion point and holding pressure size)) which can minimize the deformation amount of the preform mold were derived through CAE without applying the experimental design method. Also, the derived injection molding process conditions were applied during actual injection molding and the degree of deformation of the formed preform mold was compared with the analysis results. It is expected that plastic film having various shapes in addition to hemispherical shape using the preform mold produced through this study will be useful for the molding preform molding technology and cast molding technology.
Abstract
Traditional cell culture(2-dimensional) is the method that provide a nutrient and environment on a flat surface to cultivate cells into a single layer. Since the cell characteristics of 2D culture method is different from the characteristics of the cells cultured in the body, attempts to cultivate the cells in an environment similar to the body environment are actively proceeding in the industry, academy, and research institutes. In this study, we will develop a technology to fabricate micro-structures capable of culturing cells on surfaces with various curvatures, surface shapes, and characteristics. In order to fabricate the hemispheric plastic structure(thickness 50 ㎛), plastic preform mold (hereinafter as "preform mold") corresponding to the hemisphere was first prepared by injection molding in order to fabricate a two - layer structure to be combined with a flat plastic film. Then, thermoplastic polymer dissolved in an organic solvent was solidified on a preform mold. As a preliminary study, we proposed injection molding conditions that can minimize X/Y/Z axis deflection value. The effects of the following conditions on the preform mold were analyzed through injection molding CAE, [(1) coolant inlet temperature, (2) injection time, (3) packing pressure, (4) volume-pressure (V/P). As a result, the injection molding process conditions (cooling water inlet temperature, injection time, holding pressure condition (V / P conversion point and holding pressure size)) which can minimize the deformation amount of the preform mold were derived through CAE without applying the experimental design method. Also, the derived injection molding process conditions were applied during actual injection molding and the degree of deformation of the formed preform mold was compared with the analysis results. It is expected that plastic film having various shapes in addition to hemispherical shape using the preform mold produced through this study will be useful for the molding preform molding technology and cast molding technology.
참고문헌 (10)
- Bergenstock, M. K., "Polystyrene scaffolds: A novel tool for in vitro three-dimensional cancer models", Presented at the First AACR International Conference on Frontiers in Basic Cancer Research, pp.8~11 (2009)
- Fisher, K. E., "Tumor cell invasion of collagen matrices requires coordinate lipid agonist-induced G-protein and membrane-type matrix metalloproteinase-1-dependent signaling", Mol Cancer, 5(69) (2006)
- Kobayashi, K., "Increased expression of drug-metabolizing enzymes in human hepatocarcinoma FLC-4 cells cultured on micro-space cell culture plates", Drug Metab Pharmacokinet, 27(5), pp.478~485 (2012)
- Kermanizadeh, A., "Hepatic toxicology following single and multiple exposure of engineered nanomaterials utilising a novel primary human 3D liver microtissue model", Part Fibre Toxicol, 11(56) (2014)
- Ivanov, D. P., "Multiplexing spheroid volume, resazurin and acid phosphatase viability assays for high-throughput screening of tumour spheroids and stem cell neurospheres", PLoS One., 9(8), pp.e103817~ (2014)
- Jang, M., "On-chip three-dimensional cell culture in phaseguides improves hepatocyte functions in vitro", Biomicrofluidics, 9(3), pp.034113~ (2015)
- J. Y. Park, "Design and consideration of flow and cooling system of multiple cavity injection mold for uniform quality of lens part in plastic preform", Presented at the KSPE 2019 Spring Conference, pp.9~11 (2018)
- 김희종, "QFD와 다구찌 기법을 이용한 커넥터 사출성형공정 개선 방안", 석사, 산업경영공학, pp.2010
- 허용정, "CAE와 실험계획법을 연계한 사출 성형 시스템 최적화에 관한 연구", 한국산학기술학회논문지, 7(3), pp.271~277 (2006), 한국산학기술학회
- S. H. Tang, "Design and thermal analysis of plastic injection mould", Journal of Materials Processing Technology, 171, pp.259~267 (2006)
