유한요소해석을 이용한 마이크로 분사 노즐 특성 평가
Evaluation of micro jet nozzle using finite elements method
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In the drug delivery system industry, the technology with even split injection becomes important for maximizingefficiency and minimizing the side effects. In conventional drug delivery system, infection can occur due to pain andsplashing. Also, various applications are impossible due to disposable use, and it is the reason to avoid to use this systembecause of the complexity of the driving method. Therefore, in this study, a painless drug delivery device is developedfor non-pain with electrical insulation breakdown method. Finite elements analysis was used to evaluate the ejectioncharacteristics of drugs according to the shape of the micro ejection nozzle. The effect of the number of holes in themicro nozzle, the length of the nozzle and the inner shape of the nozzle on the drug discharge characteristics wereanalyzed.
Abstract
In the drug delivery system industry, the technology with even split injection becomes important for maximizingefficiency and minimizing the side effects. In conventional drug delivery system, infection can occur due to pain andsplashing. Also, various applications are impossible due to disposable use, and it is the reason to avoid to use this systembecause of the complexity of the driving method. Therefore, in this study, a painless drug delivery device is developedfor non-pain with electrical insulation breakdown method. Finite elements analysis was used to evaluate the ejectioncharacteristics of drugs according to the shape of the micro ejection nozzle. The effect of the number of holes in themicro nozzle, the length of the nozzle and the inner shape of the nozzle on the drug discharge characteristics wereanalyzed.
참고문헌 (6)
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- Menezes, V., "Shock Wave Driven Liquid Microjets for Drug Delivery", Journal of Applied Physics, 106, pp.086102~ (2009)