Metastasis of Renal Cell Carcinoma to the Mandible: A Case Report
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Tumors metastasizing to the oral cavity are uncommon and comprise only approximately 1% of the neoplasms in the oral cavity. A 76-year-old man was referred from a local dental clinic with a 3-month history of swelling and pain in the right side of the mandible. He reported a history of clear-cell renal cell carcinoma in the left kidney treated by nephrectomy 18 years ago. Additionally, he had undergone right-upper lobectomy of the lungs for clear-cell renal cell carcinoma metastasis 13 years previously. Orthopantomogram showed multilocular radiolucent lesion in the right posterior region of the mandible. Computed tomography revealed a 3.5×4.0-cm sized lobulated contour mass with bone destruction in the right mandibular angle. Moreover, he underwent segmental mandibulectomy with excision of the lesion under general anesthesia, followed by reconstruction using a reconstruction plate. The postoperative histological diagnosis was clear-cell renal cell carcinoma. The kidneys did not show any evidence of recurrence.
Abstract
Tumors metastasizing to the oral cavity are uncommon and comprise only approximately 1% of the neoplasms in the oral cavity. A 76-year-old man was referred from a local dental clinic with a 3-month history of swelling and pain in the right side of the mandible. He reported a history of clear-cell renal cell carcinoma in the left kidney treated by nephrectomy 18 years ago. Additionally, he had undergone right-upper lobectomy of the lungs for clear-cell renal cell carcinoma metastasis 13 years previously. Orthopantomogram showed multilocular radiolucent lesion in the right posterior region of the mandible. Computed tomography revealed a 3.5×4.0-cm sized lobulated contour mass with bone destruction in the right mandibular angle. Moreover, he underwent segmental mandibulectomy with excision of the lesion under general anesthesia, followed by reconstruction using a reconstruction plate. The postoperative histological diagnosis was clear-cell renal cell carcinoma. The kidneys did not show any evidence of recurrence.
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