Adenoid Cystic Carcinoma on the Palate Mimicking Benign Tumor: A Case Report with Literature Review
1
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Adenoid cystic carcinoma is a malignant tumor of minor salivary origin that occurs in people in their 50s and 60s, and most commonly occurs in the palate. The lesion grows slowly and, in some cases, its clinical symptoms are unremarkable; therefore, it can be easily overlooked. Complete surgical resection and additional radiation therapy have been reported to improve survival rates. The lesion spreads via perineural invasion, and when distant metastasis occurs, the prognosis is poor. Therefore, the 5-year survival rate was relatively high, whereas the 10-year survival rate was low. In this study, we report that a lesion that existed in the oral cavity for a long time and was initially diagnosed as a benign lesion clinically, but was finally diagnosed as adenoid cystic carcinoma by histopathological examination. The purpose is to emphasize the importance of early detection in local or lower-level hospitals by discussing diagnosis, treatment, and prognosis through literature review.
Abstract
Adenoid cystic carcinoma is a malignant tumor of minor salivary origin that occurs in people in their 50s and 60s, and most commonly occurs in the palate. The lesion grows slowly and, in some cases, its clinical symptoms are unremarkable; therefore, it can be easily overlooked. Complete surgical resection and additional radiation therapy have been reported to improve survival rates. The lesion spreads via perineural invasion, and when distant metastasis occurs, the prognosis is poor. Therefore, the 5-year survival rate was relatively high, whereas the 10-year survival rate was low. In this study, we report that a lesion that existed in the oral cavity for a long time and was initially diagnosed as a benign lesion clinically, but was finally diagnosed as adenoid cystic carcinoma by histopathological examination. The purpose is to emphasize the importance of early detection in local or lower-level hospitals by discussing diagnosis, treatment, and prognosis through literature review.
참고문헌 (19)
- Gondivkar SM, "Adenoid cystic carcinoma : a rare clinical entity and literature review", Oral Oncol, 47, pp.231~236 (2011)
- Mehta DN, "Adenoid cystic carcinoma of palate", J Nat Sci Biol Med, 4, pp.249~252 (2013)
- Fang Y, "Current opinions on diagnosis and treatment of adenoid cystic carcinoma", Oral Oncol, 130, pp.105945~ (2022)
- Shum JW, "Adenoid cystic carcinoma of the minor salivary glands : a retrospective series of 29 cases and review of the literature", Oral Surg Oral Med Oral Pathol Oral Radiol, 121, pp.210~214 (2016)
- Gu B, "Prognostic factors of palatal adenoid cystic carcinoma : a single-center analysis of 85 cases", Laryngoscope Investig Otolaryngol, 9, pp.e1236~ (2024)
- Huang CG, "Analysis of cytological misdiagnosis and oversight of adenoid cystic carcinoma of salivary gland", Cancer Control, 30, pp.10732748221131652~ (2023)
- He J-f, "Analysis of the clinicopathological characteristics and prognosis of adenoid cystic carcinoma of the intraoral minor salivary glands : a retrospective study of 40 cases", Int J Oral Maxillofac Surg, 50, pp.444~450 (2021)
- Gupta M, "Pleomorphic adenoma of the hard palate", BMJ Case Rep (2013)
- Ural A, "Approach to benign tumors of the palate : analysis of 28 cases", Ear Nose Throat J, 90, pp.382~385 (2011)
- Alhedaithy AA, "Schwannoma originating in the soft palate : a case report", Int J Surg Case Rep, 84, pp.106108~ (2021)
- Feller L, "Oral squamous cell carcinoma : epidemiology, clinical presentation and treatment", J Cancer Ther, 3 (2012)
- Binahmed A, "Treatment outcomes in squamous cell carcinoma of the maxillary alveolus and palate : a population-based study", Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 105, pp.750~754 (2008)
- Chung CK, "Squamous cell carcinoma of the hard palate", Int J Radiat Oncol Biol Phys, 5, pp.191~196 (1979)
- Yaga US, "Adenoid cystic carcinoma of the palate : case report and review of literature", Pan Afr Med J, 31(24), pp.106~ (2016)
- Ruhlmann V, "Diagnostic accuracy of 18 F-FDG PET", CT and MR imaging in patients with adenoid cystic carcinoma, 2017, pp.17, 1~7
- Lee PP, "Delayed diagnosis of palatal adenoid cystic carcinoma : review of diagnostic workup and image features of perineural spread", Oral Oncol, 121, pp.105501~ (2021)
- Ju J, "The role of perineural invasion on head and neck adenoid cystic carcinoma prognosis : a systematic review and meta-analysis", Oral Surg Oral Med Oral Pathol Oral Radiol, 122, pp.691~701 (2016)
- Cheng Y, "Prognosis of adenoid cystic carcinoma in head and neck region treated with different regimens-a single-centre study", Cancer Med, 12, pp.2368~2377 (2023)[DOI]
- Li C, "Study of surgery combined with 125I brachytherapy for adenoid cystic carcinoma of oral and maxillofacial region", Beijing Da Xue Xue Bao Yi Xue Ban, 51, pp.49~52 (2019)
