열과 발진을 주소로 응급실을 방문한 47일 여아에서 진단된 신생아 루푸스
A case of neonatal lupus presenting with fever and skin rash in a 47-day-old girl
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Neonatal lupus (NL) is a passively acquired autoimmune disease that occurs in infants born from asymptomatic mothers having anti-SSA or anti-SSB antibody. Infants with NL may show symptoms of systemic lupus erythematosus, including skin rash, congenital heart block, hepatic dysfunction, and hematological abnormalities. Mothers of the infants are asymptomatic or diagnosed with autoimmune diseases. When infants born to asymptomatic mothers who have never been diagnosed with the diseases show symptoms of NL, they may be mistaken for having infections. We report an NL case of a 47-day-old girl who presented to the emergency department with fever and skin rash.
Abstract
Neonatal lupus (NL) is a passively acquired autoimmune disease that occurs in infants born from asymptomatic mothers having anti-SSA or anti-SSB antibody. Infants with NL may show symptoms of systemic lupus erythematosus, including skin rash, congenital heart block, hepatic dysfunction, and hematological abnormalities. Mothers of the infants are asymptomatic or diagnosed with autoimmune diseases. When infants born to asymptomatic mothers who have never been diagnosed with the diseases show symptoms of NL, they may be mistaken for having infections. We report an NL case of a 47-day-old girl who presented to the emergency department with fever and skin rash.
참고문헌 (14)
- Bridge RG, "Placental transmission of the lupus erythematosus factor", Am J Med Sci, 227, pp.1~8 (1954)
- McCuistion CH, "Possible discoid lupus erythematosus in newborn infant. Report of a case with subsequent development of acute systemic lupus erythematosus in mother", Arch Dermatol, 119, pp.615~618 (1983)
- Lee LA, "The clinical spectrum of neonatal lupus", Arch Dermatol Res, 301, pp.107~110 (2009)
- Buyon JP, "Neonatal lupus : basic research and clinical perspectives", Rheum Dis Clin North Am, 31, pp.299~313 (2005)
- Cimaz R, "Incidence and spectrum of neonatal lupus erythematosus : a prospective study of infants born to mothers with anti-Ro autoantibodies", J Pediatr, 142, pp.678~683 (2003)
- Lee LA, "Neonatal lupus : clinical features and management", Paediatr Drugs, 6, pp.71~78 (2004)
- 강진한, "Febrile Illness with Skin Rashes", Infection and Chemotherapy, 47(3), pp.155~166 (2015), 대한감염학회
- Philopena RL, "Emergency department management of rash and fever in the pediatric patient", Pediatr Emerg Med Pract, 17, pp.1~24 (2020)
- Weston WL, "The clinical spectrum of anti-Ro-positive cutaneous neonatal lupus erythematosus", J Am Acad Dermatol, 40, pp.675~681 (1999)
- Boh EE, "Neonatal lupus erythematosus", Clin Dermatol, 22, pp.125~128 (2004)
- Abiodun M, "Neonatal lupus syndrome in a Nigerian child", BMJ Case Rep, 2012, pp.bcr0120125~ (2012)
- Vanoni F, "Neonatal systemic lupus erythematosus syndrome : a comprehensive review", Clin Rev Allergy Immunol, 53, pp.469~476 (2017)
- Martin V, "Longterm followup of children with neonatal lupus and their unaffected siblings", Arthritis Rheum, 46, pp.2377~2383 (2002)
- Wisuthsarewong W, "Neonatal lupus erythematosus : clinical character, investigation, and outcome", Pediatr Dermatol, 28, pp.115~121 (2011)