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Listeria meningitis with rapid progression of hydrocephalus: a case of a 16-month-old girl with febrile status epilepticus as the first symptom

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주제분류소아과학

초록

Listeria monocytogenes is a rare cause of bacterial meningitis, particularly beyond the neonatal period. This article describes a 16-month-old girl who presented with a new-onset febrile status epilepticus, and subsequently developed altered mentality and lethargy. L. monocytogenes was detected on a point-of-care, multiplex polymerase chain reaction using the cerebrospinal fluid. On day 3, she developed a rapidly progressive hydrocephalus. Her consciousness improved after placement of an external ventricular drain. After 3-week antibiotic therapy, she was successfully discharged without residual complications.

Abstract

Listeria monocytogenes is a rare cause of bacterial meningitis, particularly beyond the neonatal period. This article describes a 16-month-old girl who presented with a new-onset febrile status epilepticus, and subsequently developed altered mentality and lethargy. L. monocytogenes was detected on a point-of-care, multiplex polymerase chain reaction using the cerebrospinal fluid. On day 3, she developed a rapidly progressive hydrocephalus. Her consciousness improved after placement of an external ventricular drain. After 3-week antibiotic therapy, she was successfully discharged without residual complications.

참고문헌 (6)

  1. Radoshevich L, "Listeria monocytogenes : towards a complete picture of its physiology and pathogenesis", Nat Rev Microbiol, 16, pp.32~46 (2018)
  2. Ulloa-Gutierrez R, "Fulminant Listeria monocytogenes meningitis complicated with acute hydrocephalus in healthy children beyond the newborn period", Pediatric Emergency Care, 20, pp.233~237 (2004)
  3. Batra P, "Predictors of meningitis in children presenting with first febrile seizures", Pediatr Neurol, 44, pp.35~39 (2011)
  4. Murray TS, "Nelson Textbook of Pediatrics", pp.1464~ (2020), Elsevier
  5. Charlier C, "Clinical features and prognostic factors of listeriosis : the MONALISA national prospective cohort study", Lancet Infect Dis, 17, pp.510~519 (2017)
  6. Lindström J, "Assessment of the FilmArray ME panel in 4199 consecutively tested cerebrospinal fluid samples", Clin Microbiol Infect, 28, pp.79~84 (2022)

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