Neonatal Meningoencephalitis caused by Herpes Simplex Virus Type 2
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Despite its rare occurrence, early diagnosis and appropriate treatment for neonatal herpes simplex virus infection aremandatory due to its high morbidity and mortality. In Korea, there has been no epidemiologic data on neonatal herpessimplex virus infection, and even case reports are rare. We observed a 16-day-old neonate who presented with feverand seizures. We diagnosed her with meningoencephalitis caused by herpes simplex virus type 2 based on the polymerasechain reaction test, and treated her with intravenous acyclovir and anticonvulsants. The seroprevalence of herpes simplexvirus type 2 sharply increases in women in their 30s, and the average age for childbirth has increased to older than 30years of age in Korea; we therefore expect that the incidence of neonatal herpes simplex virus type 2 infection will risein Korea, and more attention should be directed to neonatal herpes simplex virus type 2 infection. We report this newbornpatient’s case along with a literature review.
Abstract
Despite its rare occurrence, early diagnosis and appropriate treatment for neonatal herpes simplex virus infection aremandatory due to its high morbidity and mortality. In Korea, there has been no epidemiologic data on neonatal herpessimplex virus infection, and even case reports are rare. We observed a 16-day-old neonate who presented with feverand seizures. We diagnosed her with meningoencephalitis caused by herpes simplex virus type 2 based on the polymerasechain reaction test, and treated her with intravenous acyclovir and anticonvulsants. The seroprevalence of herpes simplexvirus type 2 sharply increases in women in their 30s, and the average age for childbirth has increased to older than 30years of age in Korea; we therefore expect that the incidence of neonatal herpes simplex virus type 2 infection will risein Korea, and more attention should be directed to neonatal herpes simplex virus type 2 infection. We report this newbornpatient’s case along with a literature review.
참고문헌 (16)
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