본문 바로가기
KERD
논문KCI 등재

Obscure gastrointestinal bleeding in a patient with factor VII deficiency: a case controlled with tranexamic acid

김유빈|최영배|정규화
대한소아응급의학회 (Korean Society of Pediatric Emergency Medicine)|2024.01|대한소아응급의학회지 (Pediatric Emergency Medicine Journal)|제11권 제1호|pp. 51-56

0

조회

0

다운로드

0

인용

0

참고문헌

키워드

EndoscopyGastrointestinalBlood Coagulation DisordersBlood Coagulation FactorsGastrointestinal HemorrhageTranexamic Acid
주제분류소아과학

초록

Factor VII deficiency is a rare, inherited coagulopathy, which can lead to prolonged bleeding. Here, we present a case report of an adolescent with factor VII deficiency who experienced small bowel bleeding that was successfully treated with tranexamic acid. This case highlights the potential use of tranexamic acid as an effective therapeutic option for managing gastrointestinal bleeding in patients with hemostatic insufficiency of unknown etiology.

Abstract

Factor VII deficiency is a rare, inherited coagulopathy, which can lead to prolonged bleeding. Here, we present a case report of an adolescent with factor VII deficiency who experienced small bowel bleeding that was successfully treated with tranexamic acid. This case highlights the potential use of tranexamic acid as an effective therapeutic option for managing gastrointestinal bleeding in patients with hemostatic insufficiency of unknown etiology.

참고문헌 (18)

  1. Yoon HS, "Epidemiology of congenital bleeding disorders : a nationwide population-based Korean study", J Korean Med Sci, 35, pp.e350~ (2020)
  2. Korea Hemophilia Foundation, "2018 Annual report", pp.14~ (2018), Korea Hemophilia Foundation
  3. Wang K, "Tranexamic acid-a narrative review for the emergency medicine clinician", Am J Emerg Med, 56, pp.33~44 (2022)
  4. Lin S, "Obscure gastrointestinal bleeding", Gastroenterol Clin North Am, 34, pp.679~698 (2005)
  5. Awadie H, "Obscure-overt gastrointestinal bleeding : a review", Pol Arch Intern Med, 132, pp.16253~ (2022)
  6. Casciani E, "MR Enterography in paediatric patients with obscure gastrointestinal bleeding", Eur J Radiol, 93, pp.209~216 (2017)
  7. Rockey DC, "Occult gastrointestinal bleeding", N Engl J Med, 341, pp.38~46 (1999)
  8. Baker RD, "Gastrointestinal bleeds", Pediatr Rev, 42, pp.546~557 (2021)
  9. Mariani G, "Factor VII deficiency", Semin Thromb Hemost, 35, pp.400~406 (2009)
  10. Sevenet PO, "Factor VII Deficiency : From basics to clinical laboratory diagnosis and patient management", Clin Appl Thromb Hemost, 23, pp.703~710 (2017)
  11. Napolitano M, "Factor VII deficiency : clinical phenotype, genotype and therapy", J Clin Med, 6, pp.38~ (2017)
  12. CRASH-2 trial collaborators, "Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage(CRASH-2) : a randomised, placebo-controlled trial", Lancet, 376, pp.23~32 (2010)
  13. WOMAN Trial Collaborators, "Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage(WOMAN) : an international, randomised, double-blind, placebo-controlled trial", Lancet, 389, pp.2105~2116 (2017)
  14. Schutgens REG, "Tranexamic acid is not a universal hemostatic agent", Hemasphere, 5, pp.e625~ (2021)
  15. Gluud LL, "Tranexamic acid for upper gastrointestinal bleeding", Cochrane Database Syst Rev, 1, pp.CD006640~ (2012)
  16. Burke E, "Is there a role for tranexamic acid in upper GI bleeding? A systematic review and meta-analysis", Surg Res Pract, 2021, pp.8876991~ (2021)
  17. Eghbali A, "Efficacy of tranexamic acid for the prevention of bleeding in patients with von Willebrand disease and Glanzmann thrombasthenia : a controlled, before and after trial", Haemophilia, 22, pp.e423~e426 (2016)
  18. Lanzkowsky P, "Lanzkowsky’s manual of pediatric hematology and oncology", pp.287~340 (2016), Elsevier

관련 논문AI추천

Moderate Hemophilia B Diagnosed by Massive Gastrointestinal Hemorrhage on the First Day of Life: A Case Report and Literature Review박숙현, 최병호대한신생아학회 · Neonatal medicine2016 · 제23권 제4호Acquired Hemophilia A with Gastrointestinal Bleeding장진석, 차재황, Narae Park대한소화기내시경학회 · Clinical Endoscopy2020 · 제53권 제1호A Case of Congenital Factor VII Deficiency Presented with Subacute Subdural Hematoma김경옥, 김민경, 신상준, 이경희, 조희순, 현명수영남대학교 의과대학 · Journal of Yeungnam Medical Science2004 · 제21권 제2호소아에서 내시경 검사의 출혈 위험 예측 인자로서 혈액 응고 검사 및 혈소판 검사의 의의고재성, 서정기, 양혜란, 이은혜대한소아소화기영양학회 · Pediatric Gastroenterology, Hepatology & Nutrition2010 · 제13권 제1호Three Year Old Male with Multiple Dieulafoy Lesions Treated with Epinephrine Injections via Therapeutic EndoscopyChristina L. Baldwin, Michael Wilsey대한소아소화기영양학회 · Pediatric Gastroenterology, Hepatology & Nutrition2016 · 제19권 제4호Diagnosis and Management of Post-Partum Hemorrhage Caused by Acquired Hemophilia A: A Case ReportAveen M. Raouf Abdulqader, Nawshirwan G. Rashid, Shaema Salih Amin대한임상검사과학회 · 대한임상검사과학회지2022 · 제54권 제2호

이 간행물의 다른 논문 (7건)

The pattern of emergency department utilization in pediatric patients who underwent interfacility transfers from the emergency department: a nationwide population-based study in South Korea, 2016-2018김윤정, 김민지, 안신, 김원영pp. 1-10A study on the characteristics of patients visiting the pediatric emergency department with post-tonsillectomy hemorrhage곽영호, 정재윤, 김도균, 김진희, 박중완, 장혜윤, 이의준, 이하니pp. 11-16Incidence, severity, and clinical characteristics of lower respiratory tract infections in children before and after the coronavirus disease 2019 lockdown: a Dutch single-center studyMatthijs D. Kruizinga, Marjolijn C. M. Nagelkerke, Maud van Zagten, Arwen Sprij, Jolita Bekhof, Mirjam van Veenpp. 17-27Profile of pediatric ophthalmic referrals in a single emergency department in Korea정승아, 김정헌, 차윤호pp. 28-38마스크 착용 의무 해제 이후 응급실 소아 환자의 방문 양상 변화 분석장희진, 조형래, 류정민, 박준성, 김다현, 전민교, 신채호, 한지호, 이종승pp. 39-47
원문 보기