국내 고유 건강영향 평가를 위한 방사선유발갑상선암 리스크 모델 적용방안
Application Plan of the Radiation-induced Thyroid Cancer Risk Model for the Domestic-specific Health Effect Assessment of the Koreans
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초록
As part of various efforts to improve safety since the Fukushima disaster, a level 3 PSAwas enacted as a notice in Korea. For the domestic level 3 PSA, it is essential to formulate theKorean-specific health effect assessment model typically aimed at deriving lifetime risk resultingfrom radiation exposure using cancer incidence model for each cancer site. Of the cancer sites to beevaluated, more attention is required for the thyroid cancer since there is an obvious relationshipbetween the cancer risk and exposure dose. In this study, for the purpose of developing the Koreanmodel for assessing thyroid cancer risk, the following models that were widely used around theworld have been reviewed as the reference; (1) BEIR VII, (2) EPA 2011, (3) Veiga et al. (2016), and (4)Preston et al. (2007). In this review process, the following points were considered: (1) considerationof relationship between time since exposure and thyroid cancer risk, (2) similarity of ethniccharacteristics with the Koreans, and (3) exclusion of medical exposure data. From this point ofview, the Preston et al. (2007) was chosen as the most appropriate reference model. Unlike othermodels, to include both ERR and EAR models in assessing the cancer risk, the weighting factorfor risk transfer must be considered. In this study, it is suggested to use the 0.5 of weighting factorfor each model with reference to the WHO model. However, the cancer risk estimates using thisfactor should be supplemented by the uncertainty analysis. In future, the thyroid cancer risk modelproposed in this study is supposed to be installed as part of the health effect assessment module inthe Korean level 3 PSA code system, and be utilized to estimate the radiation-induced thyroid cancerrisk reflecting ethnic and regional characteristics of the Korean population.
Abstract
As part of various efforts to improve safety since the Fukushima disaster, a level 3 PSAwas enacted as a notice in Korea. For the domestic level 3 PSA, it is essential to formulate theKorean-specific health effect assessment model typically aimed at deriving lifetime risk resultingfrom radiation exposure using cancer incidence model for each cancer site. Of the cancer sites to beevaluated, more attention is required for the thyroid cancer since there is an obvious relationshipbetween the cancer risk and exposure dose. In this study, for the purpose of developing the Koreanmodel for assessing thyroid cancer risk, the following models that were widely used around theworld have been reviewed as the reference; (1) BEIR VII, (2) EPA 2011, (3) Veiga et al. (2016), and (4)Preston et al. (2007). In this review process, the following points were considered: (1) considerationof relationship between time since exposure and thyroid cancer risk, (2) similarity of ethniccharacteristics with the Koreans, and (3) exclusion of medical exposure data. From this point ofview, the Preston et al. (2007) was chosen as the most appropriate reference model. Unlike othermodels, to include both ERR and EAR models in assessing the cancer risk, the weighting factorfor risk transfer must be considered. In this study, it is suggested to use the 0.5 of weighting factorfor each model with reference to the WHO model. However, the cancer risk estimates using thisfactor should be supplemented by the uncertainty analysis. In future, the thyroid cancer risk modelproposed in this study is supposed to be installed as part of the health effect assessment module inthe Korean level 3 PSA code system, and be utilized to estimate the radiation-induced thyroid cancerrisk reflecting ethnic and regional characteristics of the Korean population.
참고문헌 (14)
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