Routine Application of the Korean FRAX Model in Women: a Single-center Study
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참고문헌
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초록
Objectives: The objective of this study was to assess the efficacy of the Korean fracture-risk assessment tool (FRAX)model for routine application in women who had a general check-up for bone mineral density (BMD). Methods: This retrospective study was conducted at a university hospital and comprised 343 patients, whose BMD and clinical risk factors were assessed for FRAX calculation. The 10-year probabilities of hip and major osteoporotic fractures were compared with the result of the FRAX® tool (http://www.shef.ac.uk/FRAX, web version 3.5) applied to Korean models developed at the World Health Organization Collaborating Center with or without femoral neck bone mineral density. Results: The T-score gradually decreased with increasing age. Additionally, the 10-year probability of a major osteoporotic fracture increased with age. However, the probability of hip fracture showed no correlation with age if BMD was not included in the estimation. Conclusion: Previous report on patients whose probability of a proximal femoral fracture were calculated using Korean FRAX models produced a higher score than our data because our data involved a general population. A larger general population is needed to confirm the Korean FRAX model. However, our data provide information for physicians to assess the Korean FRAX model in the general female population.
Abstract
Objectives: The objective of this study was to assess the efficacy of the Korean fracture-risk assessment tool (FRAX)model for routine application in women who had a general check-up for bone mineral density (BMD). Methods: This retrospective study was conducted at a university hospital and comprised 343 patients, whose BMD and clinical risk factors were assessed for FRAX calculation. The 10-year probabilities of hip and major osteoporotic fractures were compared with the result of the FRAX® tool (http://www.shef.ac.uk/FRAX, web version 3.5) applied to Korean models developed at the World Health Organization Collaborating Center with or without femoral neck bone mineral density. Results: The T-score gradually decreased with increasing age. Additionally, the 10-year probability of a major osteoporotic fracture increased with age. However, the probability of hip fracture showed no correlation with age if BMD was not included in the estimation. Conclusion: Previous report on patients whose probability of a proximal femoral fracture were calculated using Korean FRAX models produced a higher score than our data because our data involved a general population. A larger general population is needed to confirm the Korean FRAX model. However, our data provide information for physicians to assess the Korean FRAX model in the general female population.
참고문헌 (9)
- So GY, "Feasibility of FRAX for prediction of osteoporotic vertebral fractures in Korea", Asian Spine J, 6, pp.22~28 (2012)
- Tae-Hee Kim, "A Difference of Bone Fracture Rate and Frequency to Have Determined in Diagnosis Standards", OSTEOPOROSIS, 8(3), pp.266~270 (2010), 대한골다공증학회
- 지형민, "고관절 골절환자에서 한국인 FRAX^® 모델의 효용성", OSTEOPOROSIS, 9(2), pp.170~174 (2011), 대한골다공증학회
- 장선미, "골다공증 환자의 의료이용 양상", Endocrinology and Metabolism, 25(4), pp.326~339 (2010), 대한내분비학회
- 김태희, "폐경 전후 여성의 골다공증 관리의 차이", 대한폐경학회지, 17(1), pp.21~26 (2011), 대한폐경학회[DOI]
- 정수호, "부천 지역 폐경 여성에서 비타민 D 상태와 골밀도의 연관성", OSTEOPOROSIS, 7(3), pp.198~202 (2009), 대한골다공증학회
- 김태희, "과거 임신력과 골다공증에 대한 연관성", OSTEOPOROSIS, 9(1), pp.89~92 (2011), 대한골다공증학회
- Kanis JA, "Development and use of FRAX in osteoporosis", Osteoporos Int, 21(Suppl 2), pp.S407~S413 (2010)
- 이동윤, "Determination of an Applicable FRAX Model in Korean Women", Journal of Korean Medical Science, 25(11), pp.1657~1660 (2010), 대한의학회