Rodent Model of Muscular Atrophy for Sarcopenia Study
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The hallmark symptom of sarcopenia is the loss of muscle mass and strength without the loss of overall body weight. Sarcopenia patients are likely to have worse clinical outcomes and higher mortality than do healthy individuals. The sarcopenia population shows an annual increase of ~0.8% in the population after age 50, and the prevalence rate is rapidly increasing with the recent worldwide aging trend. Based on International Classification of Diseases, Tenth Revision, a global classification of disease published by the World Health Organization, issued the disease code (M62.84) given to sarcopenia in 2016. Therefore, it is expected that the study of sarcopenia will be further activated based on the classification of disease codes in the aging society. Several epidemiological studies and meta-analyses have looked at the correlation between the prevalence of sarcopenia and several environmental factors. In addition, studies using cell lines and rodents have been done to understand the biological mechanism of sarcopenia. Laboratory rodent models are widely applicable in sarcopenia studies because of the advantages of time savings, cost saving, and various analytical applications that could not be used for human subjects. The rodent models that can be applied to the sarcopenia research are diverse, but a simple and fast method that can cause atrophy or aging is preferred. Therefore, we will introduce various methods of inducing muscular atrophy in rodent models to be applied to the study of sarcopenia.
Abstract
The hallmark symptom of sarcopenia is the loss of muscle mass and strength without the loss of overall body weight. Sarcopenia patients are likely to have worse clinical outcomes and higher mortality than do healthy individuals. The sarcopenia population shows an annual increase of ~0.8% in the population after age 50, and the prevalence rate is rapidly increasing with the recent worldwide aging trend. Based on International Classification of Diseases, Tenth Revision, a global classification of disease published by the World Health Organization, issued the disease code (M62.84) given to sarcopenia in 2016. Therefore, it is expected that the study of sarcopenia will be further activated based on the classification of disease codes in the aging society. Several epidemiological studies and meta-analyses have looked at the correlation between the prevalence of sarcopenia and several environmental factors. In addition, studies using cell lines and rodents have been done to understand the biological mechanism of sarcopenia. Laboratory rodent models are widely applicable in sarcopenia studies because of the advantages of time savings, cost saving, and various analytical applications that could not be used for human subjects. The rodent models that can be applied to the sarcopenia research are diverse, but a simple and fast method that can cause atrophy or aging is preferred. Therefore, we will introduce various methods of inducing muscular atrophy in rodent models to be applied to the study of sarcopenia.
참고문헌 (103)
- Rosenberg IH, "Summary comments", Am J Clin Nutr, 50, pp.1231~1233 (1989)
- Janssen I, "Evolution of sarcopenia research", Appl Physiol Nutr Metab, 35, pp.707~712 (2010)
- "AIM coalition announces establishment of ICD-10-CM code for sarcopenia by the centers for disease control and prevention" (2016)[URL]
- Melton LJ 3rd, "Epidemiology of sarcopenia", J Am Geriatr Soc, 48, pp.625~630 (2000)
- Abellan van Kan G, "Epidemiology and consequences of sarcopenia", J Nutr Health Aging, 13, pp.708~712 (2009)
- Dennis RA, "Aging alters gene expression of growth and remodeling factors in human skeletal muscle both at rest and in response to acute resistance exercise", Physiol Genomics, 32, pp.393~400 (2008)
- Eley HL, "Effect of branched-chain amino acids on muscle atrophy in cancer cachexia", Biochem J, 407, pp.113~120 (2007)
- Deuster PA, "Endurance exercise modifies cachexia of tumor growth in rats", Med Sci Sports Exerc, 17, pp.385~392 (1985)
- Lorite MJ, "Activation of ATP-ubiquitin-dependent proteolysis in skeletal muscle in vivo and murine myoblasts in vitro by a proteolysis-inducing factor(PIF)", Br J Cancer, 85, pp.297~302 (2001)
- Adams V, "Induction of iNOS expression in skeletal muscle by IL-1beta and NFkappaB activation : an in vitro and in vivo study", Cardiovasc Res, 54, pp.95~104 (2002)
- Schindler R, "Correlations and interactions in the production of interleukin-6(IL-6), IL-1, and tumor necrosis factor(TNF)in human blood mononuclear cells : IL-6 suppresses IL-1 and TNF", Blood, 75, pp.40~47 (1990)
- Palus S, "Models of sarcopenia : Short review", Int J Cardiol, 238, pp.19~21 (2017)
- Shavlakadze T, "Of bears, frogs, meat, mice and men: complexity of factors affecting skeletal muscle mass and fat", Bioessays, 28, pp.994~1009 (2006)
- Chai RJ, "Striking denervation of neuromuscular junctions without lumbar motoneuron loss in geriatric mouse muscle", PLoS One, 6, pp.e28090~ (2011)
- Schiaffino S, "Regulation of skeletal muscle growth by the IGF1-Akt", PKB pathway : insights from genetic models, 2011, pp.1, 4~
- Giovannini S, "Modulation of GH", IGF-1 axis : potential strategies to counteract sarcopenia in older adults, 2008, pp.129, 593~601
- Tarantini S, "Age-related alterations in gait function in freely moving male C57BL", 6 mice : Translational relevance of decreased cadence and increased gait variability, 2019, pp.74, 1417~1421
- Pötsch MS, "The anabolic catabolic transforming agent(ACTA)espindolol increases muscle mass and decreases fat mass in old rats", J Cachexia Sarcopenia Muscle, 5, pp.149~158 (2014)
- Fellner C, "Diet-induced and age-related changes in the quadriceps muscle : MRI and MRS in a rat model of sarcopenia", Gerontology, 60, pp.530~538 (2014)
- Bollheimer LC, "Sarcopenia in the aging high-fat fed rat : a pilot study for modeling sarcopenic obesity in rodents", Biogerontology, 13, pp.609~620 (2012)
- Kob R, "Gender-specific differences in the development of sarcopenia in the rodent model of the ageing high-fat rat", J Cachexia Sarcopenia Muscle, 6, pp.181~191 (2015)
- Brown JC, "Sarcopenia and mortality among a population-based sample of community-dwelling older adults", J Cachexia Sarcopenia Muscle, 7, pp.290~298 (2016)
- Lawler JM, "Hindlimb unloading increases oxidative stress and disrupts antioxidant capacity in skeletal muscle", Free Radic Biol Med, 35, pp.9~16 (2003)
- Morey-Holton ER, "Hindlimb unloading rodent model: technical aspects", J Appl Physiol(1985), 92, pp.1367~1377 (2002)
- Morey ER, "Spaceflight and bone turnover : Correlation with a new rat model of weightlessness", Bioscience, 29, pp.168~172 (1979)
- Musacchia XJ, "A model for hypokinesia : effects on muscle atrophy in the rat", J Appl Physiol Respir Environ Exerc Physiol, 48, pp.479~486 (1980)
- Deavers DR, "Model for antiorthostatic hypokinesia : head-down tilt effects on water and salt excretion", J Appl Physiol Respir Environ Exerc Physiol, 49, pp.576~582 (1980)
- Stump CS, "Influence of single hindlimb support during simulated weightlessness in the rat", J Appl Physiol(1985), 68, pp.627~634 (1990)
- Bouzeghrane F, "Restraint vs. hindlimb suspension on fluid and electrolyte balance in rats", J Appl Physiol(1985), 80, pp.1993~2001 (1996)
- Hargens AR, "Tissue fluid shift, forelimb loading, and tail tension in tail-suspended rats", Physiologist, 27, pp.S37~S38 (1984)
- Globus RK, "The temporal response of bone to unloading", Endocrinology, 118, pp.733~742 (1986)
- Halloran BP, "Glucocorticoids and inhibition of bone formation induced by skeletal unloading", Am J Physiol, 255, pp.E875~E879 (1988)
- Fell RD, "Fatigue and contraction of slow and fast muscles in hypokinetic", hypodynamic rats, 1985, pp.58, 65~69
- Fitts RH, "Models of disuse: a comparison of hindlimb suspension and immobilization", J Appl Physiol(1985), 60, pp.1946~1953 (1986)
- Jaspers SR, "Atrophy and growth failure of rat hindlimb muscles in tail-cast suspension", J Appl Physiol Respir Environ Exerc Physiol, 57, pp.1472~1479 (1984)
- Templeton GH, "Influence of suspension hypokinesia on rat soleus muscle", J Appl Physiol Respir Environ Exerc Physiol, 56, pp.278~286 (1984)
- Tsika RW, "Interaction of compensatory overload and hindlimb suspension on myosin isoform expression", J Appl Physiol(1985), 62, pp.2180~2186 (1987)
- Goldspink DF, "The effect of hypokinesia and hypodynamia on protein turnover and the growth of four skeletal muscles of the rat", Pflugers Arch, 407, pp.333~340 (1986)
- Ryall JG, "Cellular and molecular mechanisms underlying age-related skeletal muscle wasting and weakness", Biogerontology, 9, pp.213~228 (2008)
- Thompson LV, "Age-related muscle dysfunction", Exp Gerontol, 44, pp.106~111 (2009)
- Delbono O, "Neural control of aging skeletal muscle", Aging Cell, 2, pp.21~29 (2003)
- Rosenberg IH, "Sarcopenia : origins and clinical relevance", J Nutr, 127, pp.990s~991s (1997)
- Luff AR, "Age-associated changes in the innervation of muscle fibers and changes in the mechanical properties of motor units", Ann N Y Acad Sci, 854, pp.92~101 (1998)
- Flood DG, "Neuron numbers and sizes in aging brain: comparisons of human, monkey, and rodent data", Neurobiol Aging, 9, pp.453~463 (1988)
- Valdez G, "Attenuation of age-related changes in mouse neuromuscular synapses by caloric restriction and exercise", Proc Natl Acad Sci U S A, 107, pp.14863~14868 (2010)
- Yang F, "Antler development was inhibited or stimulated by cryosurgery to periosteum or skin in a central antlerogenic region respectively", J Exp Zool B Mol Dev Evol, 316, pp.359~370 (2011)
- Fu SY, "Contributing factors to poor functional recovery after delayed nerve repair : prolonged denervation", J Neurosci, 15, pp.3886~3895 (1995)
- Kobayashi J, "The effect of duration of muscle denervation on functional recovery in the rat model", Muscle Nerve, 20, pp.858~866 (1997)
- Batt JA, "Tibial nerve transection-a standardized model for denervation-induced skeletal muscle atrophy in mice", J Vis Exp, pp.e50657~ (2013)
- Nagpal P, "The ubiquitin ligase Nedd4-1 participates in denervation-induced skeletal muscle atrophy in mice", PLoS One, 7, pp.e46427~ (2012)
- Plant PJ, "Absence of caspase-3 protects against denervation-induced skeletal muscle atrophy", J Appl Physiol(1985), 107, pp.224~234 (2009)
- Batt J, "Differential gene expression profiling of short and long term denervated muscle", FASEB J, 20, pp.115~117 (2006)
- Bain JR, "Improved functional recovery of denervated skeletal muscle after temporary sensory nerve innervation", Neuroscience, 103, pp.503~510 (2001)
- Sher J, "Skeletal muscle fiber types in the adult mouse", Acta Neurol Scand, 54, pp.45~56 (1976)
- Agbulut O, "Myosin heavy chain isoforms in postnatal muscle development of mice", Biol Cell, 95, pp.399~406 (2003)
- Bain JR, "Functional evaluation of complete sciatic, peroneal, and posterior tibial nerve lesions in the rat", Plast Reconstr Surg, 83, pp.129~138 (1989)
- Hare GM, "Walking track analysis : utilization of individual footprint parameters", Ann Plast Surg, 30, pp.147~153 (1993)
- McLean J, "Enhanced rate of nerve regeneration and directional errors after sciatic nerve injury in receptor protein tyrosine phosphatase sigma knock-out mice", J Neurosci, 22, pp.5481~5491 (2002)
- Varejão AS, "Functional evaluation of peripheral nerve regeneration in the rat : walking track analysis", J Neurosci Methods, 108, pp.1~9 (2001)
- Willand MP, "Electrical muscle stimulation after immediate nerve repair reduces muscle atrophy without affecting reinnervation", Muscle Nerve, 48, pp.219~225 (2013)
- Richner M, "The spared nerve injury(SNI)model of induced mechanical allodynia in mice", J Vis Exp, 54, pp.3092~ (2011)
- Rogoz K, "VGLUT2-dependent glutamatergic transmission in primary afferents is required for intact nociception in both acute and persistent pain modalities", Pain, 153, pp.1525~1536 (2012)
- Salmon AB, "Update on the oxidative stress theory of aging : does oxidative stress play a role in aging or healthy aging", Free Radic Biol Med, 48, pp.642~655 (2010)
- Fulle S, "The contribution of reactive oxygen species to sarcopenia and muscle ageing", Exp Gerontol, 39, pp.17~24 (2004)
- Sastre J, "The role of mitochondrial oxidative stress in aging", Free Radic Biol Med, 35, pp.1~8 (2003)
- Park KH, "Mechanisms of muscle denervation in aging : insights from a mouse model of amyotrophic lateral sclerosis", Aging Dis, 6, pp.380~389 (2015)
- Muller FL, "Absence of CuZn superoxide dismutase leads to elevated oxidative stress and acceleration of age-dependent skeletal muscle atrophy", Free Radic Biol Med, 40, pp.1993~2004 (2006)
- Jang YC, "Increased superoxide in vivo accelerates age-associated muscle atrophy through mitochondrial dysfunction and neuromuscular junction degeneration", FASEB J, 24, pp.1376~1390 (2010)
- Fischer LR, "Absence of SOD1 leads to oxidative stress in peripheral nerve and causes a progressive distal motor axonopathy", Exp Neurol, 233, pp.163~171 (2012)
- Fischer LR, "SOD1 targeted to the mitochondrial intermembrane space prevents motor neuropathy in the Sod1 knockout mouse", Brain, 134, pp.196~209 (2011)
- Chiu AY, "Age-dependent penetrance of disease in a transgenic mouse model of familial amyotrophic lateral sclerosis", Mol Cell Neurosci, 6, pp.349~362 (1995)
- Gurney ME, "Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation", Science, 264, pp.1772~1775 (1994)
- Tu PH, "Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions", Proc Natl Acad Sci U S A, 93, pp.3155~3160 (1996)
- Fischer LR, "Amyotrophic lateral sclerosis is a distal axonopathy : evidence in mice and man", Exp Neurol, 185, pp.232~240 (2004)
- Frey D, "Early and selective loss of neuromuscular synapse subtypes with low sprouting competence in motoneuron diseases", J Neurosci, 20, pp.2534~2542 (2000)
- Gould TW, "Complete dissociation of motor neuron death from motor dysfunction by Bax deletion in a mouse model of ALS", J Neurosci, 26, pp.8774~8786 (2006)
- Kennel PF, "Neuromuscular function impairment is not caused by motor neurone loss in FALS mice : an electromyographic study", Neuroreport, 7, pp.1427~1431 (1996)
- Brooks KJ, "MRI detects early hindlimb muscle atrophy in Gly93Ala superoxide dismutase-1(G93A SOD1)transgenic mice, an animal model of familial amyotrophic lateral sclerosis", NMR Biomed, 17, pp.28~32 (2004)
- Marcuzzo S, "Hind limb muscle atrophy precedes cerebral neuronal degeneration in G93A-SOD1 mouse model of amyotrophic lateral sclerosis : a longitudinal MRI study", Exp Neurol, 231, pp.30~37 (2011)
- Valdez G, "Shared resistance to aging and ALS in neuromuscular junctions of specific muscles", PLoS One, 7, pp.e34640~ (2012)
- Madaro L, "Unilateral immobilization : a simple model of limb atrophy in mice", Basic Appl Myol, 18, pp.149~153 (2008)
- Herbert RD, "The effect of position of immobilisation on resting length, resting stiffness, and weight of the soleus muscle of the rabbit", J Orthop Res, 11, pp.358~366 (1993)
- Ohmichi Y, "Two-week cast immobilization induced chronic widespread hyperalgesia in rats", Eur J Pain, 16, pp.338~348 (2012)
- Guo TZ, "Immobilization contributes to exaggerated neuropeptide signaling, inflammatory changes, and nociceptive sensitization after fracture in rats", J Pain, 15, pp.1033~1045 (2014)
- Aihara M, "A new model of skeletal muscle atrophy induced by immobilization using a hook-and-loop fastener in mice", J Phys Ther Sci, 29, pp.1779~1783 (2017)
- Booth FW, "Production of rat muscle atrophy by cast fixation", J Appl Physiol, 34, pp.404~406 (1973)
- Williams PE, "Connective tissue changes in immobilised muscle", J Anat, 138, pp.343~350 (1984)
- Williams PE, "The importance of stretch and contractile activity in the prevention of connective tissue accumulation in muscle", J Anat, 158, pp.109~114 (1988)
- Williams PE, "Effect of intermittent stretch on immobilised muscle", Ann Rheum Dis, 47, pp.1014~1016 (1988)
- Zemková H, "Immobilization atrophy and membrane properties in rat skeletal muscle fibres", Pflugers Arch, 416, pp.126~129 (1990)
- Karpakka J, "The effects of preimmobilization training and immobilization on collagen synthesis in rat skeletal muscle", Int J Sports Med, 11, pp.484~488 (1990)
- Onda A, "New mouse model of skeletal muscle atrophy using spiral wire immobilization", Muscle Nerve, 54, pp.788~791 (2016)
- Speacht TL, "Combination of hindlimb suspension and immobilization by casting exaggerates sarcopenia by stimulating autophagy but does not worsen osteopenia", Bone, 110, pp.29~37 (2018)
- Yuan R, "Mice as a mammalian model for research on the genetics of aging", ILAR J, 52, pp.4~15 (2011)
- Yuan R, "Aging in inbred strains of mice : study design and interim report on median lifespans and circulating IGF1 levels", Aging Cell, 8, pp.277~287 (2009)
- Barreto G, "Age-related defects in sensorimotor activity, spatial learning, and memory in C57BL", 6 mice, 2010, pp.22, 214~219
- Graber TG, "C57BL", 6 neuromuscular healthspan scoring system, 2013, pp.68, 1326~1336
- Parks RJ, "A procedure for creating a frailty index based on deficit accumulation in aging mice", J Gerontol A Biol Sci Med Sci, 67, pp.217~227 (2012)
- Vanhooren V, "The mouse as a model organism in aging research: usefulness, pitfalls and possibilities", Ageing Res Rev, 12, pp.8~21 (2013)
- Miwa S, "Low abundance of the matrix arm of complex I in mitochondria predicts longevity in mice", Nat Commun, 5, pp.3837~ (2014)
- Sayer AA, "New horizons in the pathogenesis, diagnosis and management of sarcopenia", Age Ageing, 42, pp.145~150 (2013)
- Shavlakadze T, "Delayed but excellent myogenic stem cell response of regenerating geriatric skeletal muscles in mice", Biogerontology, 11, pp.363~376 (2010)
- Aagaard P, "Role of the nervous system in sarcopenia and muscle atrophy with aging : strength training as a countermeasure", Scand J Med Sci Sports, 20, pp.49~64 (2010)
