Evaluation of bone formation after grafting with cancellous and cortical bone allografts in the treatment of bone defects around implants
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Purpose: The purpose of this study was to compare the amount of new bone formation obtained with various allogenic graft materials. Materials and methods: Sixty rats were divided into a control group, which did not receive bone grafts, a group that received bone grafts with human mineralized cancellous bone allograft material (Tutoplast®); Group 1, and a group in which freeze-dried human mineralized cortical bone cortical bone graft materials (SureOss™) were grafted to the defect area; Group 2. Rats were sacrificed after 6 weeks or 12 weeks, and the amount of new bone formation was evaluated. Results: In all treatment groups, the amount of new bone formation in the 12-week group was statistically significantly greater than in the 6-week group. In the 6-week groups, the amount of new bone formation in animals in which cancellous bone was used as the graft material was greater than that in animals in which cortical bone graft materials were used; nonetheless, this difference did not reach significance. In the 12-week groups, the amount of new bone formation in animals in which cortical bone graft materials were used was slightly greater than the amount of new bone formation in animals in which cancellous bone was used; however, this difference was not significant. Conclusion: Based on the results, it was found that allogenic bone graft materials are useful to augment the amount of new bone formation for the restoration of defect areas, and in cases in which cancellous bone graft materials were used because the initial inner surface of the defect was large, the amount of new bone formation was slightly greater.
Abstract
Purpose: The purpose of this study was to compare the amount of new bone formation obtained with various allogenic graft materials. Materials and methods: Sixty rats were divided into a control group, which did not receive bone grafts, a group that received bone grafts with human mineralized cancellous bone allograft material (Tutoplast®); Group 1, and a group in which freeze-dried human mineralized cortical bone cortical bone graft materials (SureOss™) were grafted to the defect area; Group 2. Rats were sacrificed after 6 weeks or 12 weeks, and the amount of new bone formation was evaluated. Results: In all treatment groups, the amount of new bone formation in the 12-week group was statistically significantly greater than in the 6-week group. In the 6-week groups, the amount of new bone formation in animals in which cancellous bone was used as the graft material was greater than that in animals in which cortical bone graft materials were used; nonetheless, this difference did not reach significance. In the 12-week groups, the amount of new bone formation in animals in which cortical bone graft materials were used was slightly greater than the amount of new bone formation in animals in which cancellous bone was used; however, this difference was not significant. Conclusion: Based on the results, it was found that allogenic bone graft materials are useful to augment the amount of new bone formation for the restoration of defect areas, and in cases in which cancellous bone graft materials were used because the initial inner surface of the defect was large, the amount of new bone formation was slightly greater.
참고문헌 (25)
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