본문 바로가기
KERD
논문KCI 등재

Nuclear Reprogramming in the Nuclear Transfer Embryos

김성우|박수봉|고영규|이준희
농업생명과학연구원 (Institute of Agriculture & Life Science, Gyeongsang National University)|2013|농업생명과학연구 (Journal of Agriculture & Life Science)|제47권 제1호|pp. 147-155

3

조회

0

다운로드

0

인용

0

참고문헌

키워드

Somatic cell nuclear transferChromatinNuclear architectureNuclear reprogramming

초록

Embryo reconstruction by somatic cell nuclear transfer (SCNT) has been used to demonstrate that mammalian somatic cells can dedifferentiate into a totipotent nucleus when introduced into an oocyte. This process of dedifferentiation of somatic cells after nuclear transplantation is defined as nuclear reprogramming, although this terminology gives little information on the molecular events that characterize this process. When planning on strategies for nuclear reprogramming by nuclear transfer (NT) one may suggest that converting the somatic nuclear configuration into an embryonic state is highly desirable, so this may promote a succession of events similar to those occurring during early embryo development. In the following part of this overview we will discuss the results of many studies that have investigated different aspects of nuclear remodelling after SCNT.

Abstract

Embryo reconstruction by somatic cell nuclear transfer (SCNT) has been used to demonstrate that mammalian somatic cells can dedifferentiate into a totipotent nucleus when introduced into an oocyte. This process of dedifferentiation of somatic cells after nuclear transplantation is defined as nuclear reprogramming, although this terminology gives little information on the molecular events that characterize this process. When planning on strategies for nuclear reprogramming by nuclear transfer (NT) one may suggest that converting the somatic nuclear configuration into an embryonic state is highly desirable, so this may promote a succession of events similar to those occurring during early embryo development. In the following part of this overview we will discuss the results of many studies that have investigated different aspects of nuclear remodelling after SCNT.

참고문헌 (47)

  1. Alberio, R., "Activation of bovine oocytes by specific inhibition of cyclindependent kinases", Molecular Reproduction and Development, 55, pp.422~432 (2000)
  2. Baguisi, A., "Production of goats by somatic cell nuclear transfer", Nature Biotechnology, 17, pp.456~461 (1999)
  3. Baran, V., "Nucleolar Changes in Bovine Nucleotransferred Embryos", Biology of Reproduction, 66, pp.534~543 (2002)
  4. Bordignon, V., "Transgene expression of green fluorescent protein and germ line transmission in cloned calves derived from in vitro-transfected somatic cells", Biology of Reproduction, 68, pp.2013~2023 (2003)
  5. Bourc'his, D., "Delayed and incomplete reprogramming of chromosome methylation patterns in bovine cloned embryos", Current Biology, 11, pp.1542~1546 (2001)
  6. Campbell, K. H. S., "Reprogramming the genome: role of the cell cycle", Reproduction Supplement, 61, pp.477~494 (2003)
  7. Campbell, K. H. S., "Improved development to blastocyst of ovine nuclear transfer embryos reconstructed during the presumptive S-phase of enucleated activated oocytes", Biology of Reproduction, 50, pp.1385~1393 (1994)
  8. Campbell, K. H. S., "Co-ordinating nuclear and cytoplasmic events", Reviews in Reproduction, 1, pp.40~46 (1996)
  9. Clayton, A. L., "MAP kinase-mediated phosphoacetylation of histone H3 and inducible gene regulation", FEBS Letters, 546, pp.51~58 (2003)
  10. Collas, P., "Influence of cell cycle stage of the donor nucleus on development of nuclear transplant rabbit embryos", Biology of Reproduction, 46, pp.492~500 (1992)
  11. Dean, W., "Conservation of methylation reprogramming in mammalian development: aberrant reprogramming in cloned embryos", Proceedings of the National Academy of Science USA, 98, pp.13734~13738 (2001)
  12. Du, F., "Differential cytoplast requirement for embryonic and somatic cell nuclear transfer in cattle", Molecular Reproduction and Development, 63, pp.183~191 (2002)
  13. Enright, B. P., "Epigenetic characteristics and development of embryos cloned from donor cells treated by trichostatin A or 5-aza- 2'-deoxycytidine", Biology of Reproduction, 69, pp.896~901 (2003)
  14. Fawcett, D. W, "On the occurrence of a fibrous lamina on the inner aspect of the nuclear envelope in certain cells of vertebrates", American Journal of Anatomy, 119, pp.129~145 (1966)
  15. Galasinski, S. C., "Phosphatase inhibition leads to histone deacetylases 1 and 2 phosphorylation and disruption of corepressor interactions", Journal of Biological Chemistry, 277, pp.19618~19626 (2002)
  16. Gao, S., "Rapid H1 linker histone transitions following fertilization or somatic cell nuclear transfer : evidence for a uniform developmental program in mice", Developmental Biology, 266, pp.62~75 (2004)
  17. Gregory, R. I., "Inhibition of histone deacetylases alters allelic chromatin conformation at the imprinted U2af1-rs1 locus in mouse embryonic stem cells", Journal of Biological Chemistry, 277, pp.11728~11734 (2002)
  18. Gregory, R. I., "on the imprinted genes Snrpn and U2af1-rs1", Molecular and Cellular Biology, 21, pp.5426~5436 (2001)
  19. Jenuwein, T., "Translating the histone code", Science, 293, pp.1074~1080 (2001)
  20. Kang, Y. K., "Typical demethylation events in cloned pig embryos. Clues on species- specific differences in epigenetic reprogramming of a cloned donor genome", Journal of Biological Chemistry, 276, pp.39980~39984 (2001)
  21. Kang, Y. K., "Limited demethylation leaves mosaic-type methylation states in cloned bovine pre-implantation embryos", EMBO Journal, 21, pp.1092~1100 (2002)
  22. Kelly, R., "A-type lamin dynamics in bovine somatic cell nuclear transfer embryos", Reproduction, Fertility and Development, 22, pp.956~965 (2010)
  23. Kim, J. M., "Changes in histone acetylation during mouse oocyte meiosis", Journal of Cell Biology, 162, pp.37~46 (2003)
  24. Kim, J. M., "Analysis of the mechanism for chromatin remodeling in embryos reconstructed by somatic nuclear transfer", Biology of Reproduction, 67, pp.760~766 (2002)
  25. Kubelka, M., "Without influencing chromosome condensation activity", Biology of Reproduction, 62, pp.292~302 (2000)
  26. Kurosaka, S., "Dependence of DNA synthesis and in vitro development of bovine nuclear transfer embryos on the stage of the cell cycle of donor cells and recipient cytoplasts", Biology of Reproduction, 67, pp.643~647 (2002)
  27. Laurincik, J., "Nucleolar protein allocation and ultrastructure in bovine embryos produced by nuclear transfer from granulosa cells", Molecular Reproduction and Development, 61, pp.477~487 (2002)
  28. Liu, J. L., "Effect of telophase enucleation on bovine somatic nuclear transfer", Theriogenology, 54, pp.989~998 (2000)
  29. Liu, L., "Differential inactivation of maturation-promoting factor and mitogen-activated protein kinase following parthenogenetic activation of bovine oocytes", Biology of Reproduction, 59, pp.537~545 (1998)
  30. Liu, L., "Parthenogenetic development and protein patterns of newly matured bovine oocytes after chemical activation", Molecular Reproduction and Development, 49, pp.298~307 (1998)
  31. Liu, L., "Interplay of maturation-promoting factor and mitogen- activated protein kinase inactivation during metaphase-tointerphase transition of activated bovine oocytes", Biology of Reproduction, 61, pp.1~7 (1999)
  32. Maalouf, W. E., "Acetylation of histone H4 lysine –5 and lysine –8 during development of in vitro produced bovine embryos", Reproduction Fertility and Development, 16, pp.125~ (2004)
  33. Moreira, P. N., "Architectural defects in pronuclei of mouse nuclear transplant embryos", Journal of Cell Science, 116, pp.3713~3720 (2003)
  34. Ono, Y., "Cloned mice from fetal fibroblast cells arrested at metaphase by a serial nuclear transfer", Biology of Reproduction, 64, pp.44~50 (2001)
  35. Polejaeva, I. A., "Cloned pigs produced by nuclear transfer from adult somatic cells", Nature, 407, pp.86~90 (2000)
  36. Reik, W., "Epigenetic reprogramming in mammalian development", Science, 293, pp.1089~1093 (2001)
  37. Santos, F., "Epigenetic marking correlates with developmental potential in cloned bovine preimplantation embryos", Current Biology, 13, pp.1116~1121 (2003)
  38. Schatten, G., "Nuclear lamins and peripheral nuclear antigens during fertilization and embryogenesis in mice and sea urchins", Proceedings of the National Academy of Science USA, 82, pp.4727~4731 (1985)
  39. Shi, W., "(2003)Induction of a senescent-like phenotype does not confer the ability of bovine immortal cells to support the development of nuclear transfer embryos", Biology of Reproduction, 69, pp.301~309 (2003)
  40. Shin, M. R., "Nuclear and microtubule reorganization in nuclear-transferred bovine embryos", Molecular Reproduction and Development, 62, pp.74~82 (2002)
  41. Stewart, C., "Teratocarcinoma stem cells and early mouse embryos contain only a single major lamin polypeptide closely resembling lamin B", Cell, 51, pp.383~392 (1987)
  42. Stein, P., "Stage-dependent redistributions of acetylated histones in nuclei of the early preimplantation mouse embryo", Molecular Reproduction and Development, 47, pp.421~429 (1997)
  43. Tani, T., "Direct exposure of chromosomes to nonactivated ovum cytoplasm is effective for bovine somatic cell nucleus reprogramming", Biology of Reproduction, 64, pp.324~330 (2001)
  44. Tani, T., "Reprogramming of bovine somatic cell nuclei is not directly regulated by maturation promoting factor or mitogen-activated protein kinase activity", Biology of Reproduction, 69, pp.1890~1894 (2003)
  45. Teranishi, T., "(2004)Rapid replacement of somatic linker histones with the oocyte-specific linker histone H1foo in nuclear transfer", Developmental Biology, 266, pp.76~86 (2004)
  46. Vignon, X., "Developmental potential of bovine embryos reconstructed from enucleated matured oocytes fused with cultured somatic cells", C.R.Acad.Sci. III, 321, pp.735~745 (1998)
  47. Worrad, D. M., "Temporally restricted spatial localization of acetylated isoforms of histone H4 and RNA polymerase II in the 2-cell mouse embryo", Development, 121, pp.2949~2959 (1995)

관련 논문AI추천

Influences of somatic donor cell sex on in vitro and in vivo embryo development following somatic cell nuclear transfer in pigs권덕남, 김병우, 김진회, 박미룽, 서자겸, 신택순, 유재규, 조병욱, 조성근, 최윤정아세아·태평양축산학회 · Animal Bioscience2017 · 제30권 제4호An efficient SCNT technology for the establishment of personalized and public human pluripotent stem cell banks엄진희, 이동율, 이유미, 이정은, 정영기생화학분자생물학회 · BMB Reports2016 · 제49권 제4호Nuclear transfer by using a laser-assisted zona pellucida piercing technique in mice강호인, 노상호, 민병무, 박상규, 성지혜, 최영주대한구강생물학회 · International Journal of Oral Biology2007 · 제32권 제3호Effects of Trichostatin A on In vitro Development of Porcine Embryos Derived from Somatic Cell Nuclear Transfer김연욱, 김현석, 박선우, 박치훈, 신태영, 이세영, 이종연, 정연우, 정연익, 현상환, 황우석아세아·태평양축산학회 · Animal Bioscience2013 · 제26권 제12호A Comparison of m-Carboxycinnamic Acid Bishydroxamide with Trichostatin A as Histone Deacetylase Inhibitor on the Developmental Competence of Somatic Cell Nuclear Transfer Porcine Embryos고영규, 김진욱, 김태석, 박상훈, 백상기, 성환우, 윤호백, 이미란, 이준희, 진상진농업생명과학연구원 · 농업생명과학연구2014 · 제48권 제6호Ascorbic acid increases demethylation in somatic cell nuclear transfer embryos of the pig (Sus scrofa)김현규, 남윤석, 노진구, 이승훈, 임기선, Minghui Zhao, Tai-Young Hur아세아·태평양축산학회 · Animal Bioscience2017 · 제30권 제7호

이 간행물의 다른 논문 (22건)

목제품에 투영된 산림인증의 경제적 가치 추정김동현, 김의경pp. 1-10Effects of Culture Media on Catechins and Caffeine Production in Adventitious Roots of Tea Tree (Camellia sinensis L.)황정규, 민지윤, 강성미, 김용덕, 김학곤, 심선정, 최명석, 김종갑, 문현식, 김종철pp. 11-20제주지역 ‘헤이워드’ 참다래 과원 토양의 화학적 성질과 잎의 양분조성손다니엘, 성기철, 임찬규, 김천환, 문두경, 송은영, 김성철pp. 21-28대나무 용기와 토양처리가 도라지 근계 생장에 미치는 영향권수덕, 윤준혁, 전권석, 강정희pp. 29-37Biological Seed Treatment : Viable Population Changes of Paenibacillus polymyxa on Seed and Root and its Antagonistic Activity after Seed Formulation김진우, 류충민, 최옥희pp. 39-47
원문 보기