유효성분들을 배합한 치약제의 실험실적 및 임상적 치아미백유지 효과
Tooth whitening maintenance efficacy of dentifrices containing several active ingredients in vitro and in vivo
0
조회
0
다운로드
7
인용
0
참고문헌
키워드
초록
Objectives: The purpose of this study was to investigate tooth whitening maintenance efficacy of several dentifrices containing effective ingredients for tooth whitening. Methods: Hydroxyapatite specimens(HAPs) staining was done by using modified Stookey’s methods. HAPs were treated with 2.9% hydrogen peroxide containing strip for whitening, and were shaken with several dentifrice slurry(dentifrice 1 : artificial saliva 2) for 30 minutes. The HAPs were finally dipped in staining solution for an hour. Shaking and dipping were repeated 4 times and lightness values were measured by colorimeter at each step. In clinical test, test 4 dentifrice and control dentifrice were evaluated by 21 subjects for 2 months after receiving institutional review board(IRB) approval. Organoleptic(vita shade guide) and instrumental(SHADEEYENCC) evaluation were performed for whiteness change of teeth. Statistical analysis was performed using repeated measures ANOVA, Tukey's post hoc test and χ2-test(p<0.05). Results: All dentifrices showed statistical significance in comparison with control dentifrice containing sodium fluoride and test 4 dentifrice containing sodium pyrophosphate, sodium metaphosphate, candelilla wax, and sodium fluoride showed statistical significance in comparison with other dentifrices by inhibiting staining in vitro(p<0.05). In clinical test, test 4 dentifrice showed better effects than control dentifrice in organoleptic and instrumental evaluation in tooth whitening maintenance efficacy(p<0.05). The awareness toward tooth whitening maintenance efficacy for 2 months use showed that test 4 dentifrice was much better than control dentifrice, but did not show statistically significant(p>0.05). Conclusions: Dentifrice containing sodium pyrophosphate, sodium metaphosphate, candelilla wax and sodium fluoride was more effective in keeping teeth white.
Abstract
Objectives: The purpose of this study was to investigate tooth whitening maintenance efficacy of several dentifrices containing effective ingredients for tooth whitening. Methods: Hydroxyapatite specimens(HAPs) staining was done by using modified Stookey’s methods. HAPs were treated with 2.9% hydrogen peroxide containing strip for whitening, and were shaken with several dentifrice slurry(dentifrice 1 : artificial saliva 2) for 30 minutes. The HAPs were finally dipped in staining solution for an hour. Shaking and dipping were repeated 4 times and lightness values were measured by colorimeter at each step. In clinical test, test 4 dentifrice and control dentifrice were evaluated by 21 subjects for 2 months after receiving institutional review board(IRB) approval. Organoleptic(vita shade guide) and instrumental(SHADEEYENCC) evaluation were performed for whiteness change of teeth. Statistical analysis was performed using repeated measures ANOVA, Tukey's post hoc test and χ2-test(p<0.05). Results: All dentifrices showed statistical significance in comparison with control dentifrice containing sodium fluoride and test 4 dentifrice containing sodium pyrophosphate, sodium metaphosphate, candelilla wax, and sodium fluoride showed statistical significance in comparison with other dentifrices by inhibiting staining in vitro(p<0.05). In clinical test, test 4 dentifrice showed better effects than control dentifrice in organoleptic and instrumental evaluation in tooth whitening maintenance efficacy(p<0.05). The awareness toward tooth whitening maintenance efficacy for 2 months use showed that test 4 dentifrice was much better than control dentifrice, but did not show statistically significant(p>0.05). Conclusions: Dentifrice containing sodium pyrophosphate, sodium metaphosphate, candelilla wax and sodium fluoride was more effective in keeping teeth white.
참고문헌 (23)
- Heymann HO, "Tooth whitening: facts and fallacies", Br Dent J, 198(8), pp.514~ (2005)
- 양해영, "3% hydrogen peroxide 자가미백 부착대와 프라이머 겸용에의한 치아미백 효과 평가", 한국치위생학회지, 13(5), pp.901~908 (2013), 한국치위생학회[DOI]
- "Oral care in the United States", Euromonitor International July 2013; Passport 4, ~ (2013)
- Ministry of Food and Drug Safety, "Rule book of quasi-drug", Ministry of Food and Drug Safety, 305~309 (2014)
- Joiner A, "In vitro evaluation of a novel 6% hydrogen peroxide tooth whitening product", J Dent, 32(1), pp.19~25 (2004)
- Leonard RH, "Use of different concentration of carbamide peroxide for bleaching teeth: an in vitro study", Quintessence Int, 29, pp.503~507 (1998)
- Haywood VB, "Nightguard vital bleaching: effect of various solution on enamel surface texture and color", Quintessence Int, 22, pp.775~782 (1991)
- Farrell S, "Placebo-controlled trial evaluating safety with 12-months continuous use of 6% hydrogen peroxide whitening strips", J Dent, 36, pp.726~730 (2008)
- Shahidi H, "Randomized controlled trial of 10% hydrogen peroxide whitening strips", J Clin Dent, 16, pp.91~95 (2005)
- 안재현, "과산화수소가 배합된 제제의 치아미백효과에 관한 연구", 한국치위생학회지, 14(1), pp.101~108 (2014), 한국치위생학회[DOI]
- Cho MJ, "Dental prophylaxis", pp.24~27 (2012), Komoonsa
- 남설희, "미백치약 사용에 따른 효과와 다양한 pH 음료의 재착색 평가", 치위생과학회지, 13(2), pp.191~196 (2013), 한국치위생과학회
- 김은희, "자가 미백 처치 기간 중 커피 종류별 적용이 치아 착색에 미치는 영향", 한국치위생학회지, 10(6), pp.955~963 (2010), 한국치위생학회
- 정세환, "2.6% hydrogen peroxide 부착대(strip)의 사용 6개월경과 후 치아미백효과", 대한구강보건학회지, 28(1), pp.117~125 (2004), 대한예방치과·구강보건학회
- Kim YS, "Effect of nano-carbonate apatite to prevent re-stain after dental bleaching in vitro", J Dent, 39, pp.636~642 (2011)
- 방규현, "3.0% H2O2 젤타입 미백제 사용 후 0.3% H2O2 함유 치약의 사용으로 인한 치아미백 유지효과", 대한구강보건학회지, 31(2), pp.167~175 (2007), 대한예방치과·구강보건학회
- Stookey GK, "In vitro removal of stain with dentifrices", J Dent Res, 11, pp.1236~1239 (1982)
- Kim JB, "A clinical comparison of the anticalculus effect of two kinds of therapeutic dentifrice", J Korean Acad Dent Health, 13(1), pp.7~16 (1989)
- Ma DS, "A clinical study of toothpaste containing pyrophosphate, hydroxyapatite and Vitamin-E on the prevention of calculus formation and gingivitis", J Korean Acad Dent Health, 22(1), pp.13~18 (1998)
- Ayad F, "The stain prevention efficacy of two tooth whitening dentifrices", Compend Contin Educ Dent, 23(8), pp.733~736 (2002)
- Jung SH, "Clinical study on the effect of therapeutic toothpaste containing tetrasodium pyrophosphate, vitamin E and hydrogen peroxide on the tooth whitening", J Korean Acad Dent Health, 25(2), pp.221~226 (2001)
- Cavalli V, "High-concentrated carbamide peroxide bleaching agents effects on enamel surface", J Oral Rehabil, 31(2), pp.155~159 (2004)
- 강시묵, "전문가 미백 처치 후 나노 탄산 아파타이트 함유 치약에 의한 재 착색 방지 효과", 대한구강보건학회지, 32(1), pp.42~53 (2008), 대한예방치과·구강보건학회