만 30세 이상 성인에서 치주염과 고중성지방혈증과의 연관성 : 2015년 국민건강영양조사 자료를 이용하여
Association between periodontitis and hypertriglyceridemia in Korean adults aged 30 and older : based on data from 2015 Korea National Health and Nutrition Examination Survey
1
조회
0
다운로드
3
인용
0
참고문헌
키워드
초록
Objectives: The purpose of the study was to analyze the association between dyslipidemia and periodontitis in Korean adults aged 30 and older. Methods: We examined 3,992 subjects participating in the 2015 Korean National Health and Nutrition Examination Survey. Periodontal status was evaluated using the community periodontal index (CPI). People with 3 or 4 CPI codes were classified as the periodontitis group. For statistical analyses, chi-square test and logistic multiple regression were used. Results: The prevalence of periodontitis was higher in men, people aged 70 and over, people whose income status was among the lower 25%, and people whose educational level was high school or lower (p<0.001). The prevalence of periodontitis was higher in people who brushed their teeth twice or less, those who did not use interdental cleaning devices, those who did not have a dental checkup in the last 12 months, and those who had not drunk or smoked (p<0.05). The prevalence of periodontitis was increased with individuals whose BMI was ≥25 kg/m2 , those whose glycated hemoglobin was ≥6.5%, and whose lipid levels were higher or lower than the normal range. In the logistic regression model, an increase in triglyceride was found to increase the prevalence of periodontitis (p<0.05). Conclusions: The study suggests that dyslipidemia, especially hypertriglyceridemia, is a predictor of periodontitis.
Abstract
Objectives: The purpose of the study was to analyze the association between dyslipidemia and periodontitis in Korean adults aged 30 and older. Methods: We examined 3,992 subjects participating in the 2015 Korean National Health and Nutrition Examination Survey. Periodontal status was evaluated using the community periodontal index (CPI). People with 3 or 4 CPI codes were classified as the periodontitis group. For statistical analyses, chi-square test and logistic multiple regression were used. Results: The prevalence of periodontitis was higher in men, people aged 70 and over, people whose income status was among the lower 25%, and people whose educational level was high school or lower (p<0.001). The prevalence of periodontitis was higher in people who brushed their teeth twice or less, those who did not use interdental cleaning devices, those who did not have a dental checkup in the last 12 months, and those who had not drunk or smoked (p<0.05). The prevalence of periodontitis was increased with individuals whose BMI was ≥25 kg/m2 , those whose glycated hemoglobin was ≥6.5%, and whose lipid levels were higher or lower than the normal range. In the logistic regression model, an increase in triglyceride was found to increase the prevalence of periodontitis (p<0.05). Conclusions: The study suggests that dyslipidemia, especially hypertriglyceridemia, is a predictor of periodontitis.
참고문헌 (30)
- Sbordone L, "Oral microbial biofilms and plaque-related diseases : microbial communities and their role in the shift from oral health to disease", Clin Oral Investig, 7(4), pp.181~188 (2003)
- Eaton K, "Practical Periodontics", pp.13~26 (2015), Elsevier
- Health Insurance Review and Assessment Service and National Health Insurance Service, "2018 National Health Insurance Statistical Yearbook", Health Insurance Review and Assessment Service and National Health Insurance Service, 620~622 (2019)
- Carrizales-Sepúlveda EF, "Periodontal disease, systemic inflammation and the risk of cardiovascular disease", Heart Lung Circ, 27(11), pp.1327~1334 (2018)[DOI]
- Bascones-Martínez A, "Diabetes and periodontal disease : review of the literature", Am J Dent, 27(2), pp.63~67 (2014)
- Cheng Z, "Periodontal disease and periodontal bacteria as triggers for rheumatoid arthritis", Best Pract Res Clin Rheumatol, 31(1), pp.19~30 (2017)[DOI]
- Zhou X, "Interrelationship between diabetes and periodontitis : role of hyperlipidemia", Arch Oral Biol, 60(4), pp.667~674 (2015)[DOI]
- Griffiths R, "Lipoproteins and lipoprotein metabolism in periodontal disease", Clin Lipidol, 5(3), pp.397~411 (2010)
- Kemer Doğan ES, "The effect of menopause on the relationship between hyperlipidemia and periodontal disease via salivary 8-hydroxy-2'-deoxyguanosine and myeloperoxidase levels", Acta Odontol Scand, 76(2), pp.92~97 (2018)[DOI]
- Kwon YJ, "Triglyceride to high density lipoprotein cholesterol ratio and its association with periodontal disease in Korean adults: findings based on the 2012-2014 Korean national health and nutrition examination survey", Clin Oral Investig, 22(1), pp.515~522 (2018)[DOI]
- Nepomuceno R, "Serum lipid levels in patients with periodontal disease : a meta-analysis and meta-regression", J Clin Periodontol, 44(12), pp.1192~1207 (2017)[DOI]
- Korea Health Statistics 2015: Korea National Health and Nutrition Examination Survey(KNHANES VI-3), "Ministry of Health & Welfare", Ministry of Health & Welfare, 3~5 (2016)
- WHO Expert Consultation, "Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies", Lancet, 363(9403), pp.157~163 (2004)[DOI]
- Harvard Medical School, "Harvard medical school family health guide", pp.149~166 (1999), Simon & Schuster
- Expert panel on the detection, evaluation, and treatment of high blood cholesterol in adults, "executive summary of the third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III)", JAMA, 285(19), pp.2486~2497 (2001)
- "Standard of dyslipidemia" (2019)[URL]
- Ahn YB, "The association of hypertension with periodontitis is highlighted in female adults: results from the Fourth Korea National Health and Nutrition Examination Survey", J Clin Periodontol, 42(11), pp.998~1005 (2015)[DOI]
- Lamster IB, "Periodontal disease and the metabolic syndrome", Int Dent J, 67(2), pp.67~77 (2017)[DOI]
- Morita M, "Relationship between blood triglyceride levels and periodontal status", Community Dent Health, 21(1), pp.32~36 (2004)
- Awartani F1, "Evaluation of periodontal status in subjects with hyperlipidemia", J Contemp Dent Pract, 11(2), pp.33~40 (2010)
- Han SJ, "The association between periodontitis and dyslipidemia according to smoking and harmful alcohol use in a representative sample of Korean adults", Clin Oral Investig, 24(2), pp.937~944 (2020)[DOI]
- Katz J, "Association between periodontal pockets and elevated cholesterol and low density lipoprotein cholesterol levels", J Periodontol, 73(5), pp.494~500 (2002)
- Golpasand Hagh L, "The association between hyperlipidemia and periodontal infection", Iran Red Crescent Med J, 16(12), pp.e6577~ (2014)[DOI]
- Tenenbaum A, "Hypertriglyceridemia : a too long unfairly neglected major cardiovascular risk factor", Cardiovasc Diabetol, 13, pp.159~ (2014)[DOI]
- Lutfioğlu M, "Gingival crevicular fluid oxidative stress level in patients with periodontal disease and hyperlipidemia", Braz Oral Res, 31, pp.e110~ (2017)[DOI]
- Nepomuceno R, "Systemic expression of genes related to inflammation and lipid metabolism in patients with dyslipidemia, type 2 diabetes mellitus and chronic periodontitis", Diabetes Metab Syndr, 13(4), pp.2715~2722 (2019)[DOI]
- Kafadar D, "Association of sociodemographic profile, dyslipidemias, and obesity in smoker, former smoker, and nonsmoker patients with coronary artery disease", Niger J Clin Pract, 21(9), pp.1190~1197 (2018)[DOI]
- Genco RJ, "Risk factors for periodontal disease", Periodontol 2000, 62(1), pp.59~94 (2013)[DOI]
- Bourgeois D, "Efficacy of interdental calibrated brushes on bleeding reduction in adults : a 3-month randomized controlled clinical trial", Eur J Oral Sci, 124(6), pp.566~571 (2016)[DOI]
- Lee JY, "The use of an interdental brush mitigates periodontal health inequalities: the Korean National Health and Nutrition Examination Survey (KNHANES)", BMC Oral Health, 19(1), pp.168~ (2019)[DOI]
