안면마비 회복 예측에서 순목 반사의 역할
The Role of Blink Reflex in Predicting the Recovery of Facial Palsy
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Objective To determine whether blink reflex can be used as a prognosis test for Bell’s palsy and whether it can complement the limitations of electroneurography (ENoG) as a prognostic test for Bell’s palsy. Methods This retrospective study included 99 patients diagnosed with Bell’s palsy from August 2011 to January 2017. Findings of clinical examination of facial nerve function were recorded using the House-Brackmann scale at the initial visit and follow up examination was done at the second and third visit. Electrophysiological evaluations were performed using blink reflex and ENoG tests within one month of Bell’s palsy onset. Clinical data were analyzed using Student’s T- and Chi-square tests. Results Acceptable left side R1, R2 and abnormal right side R2 latencies or abnormal left side R1, R2 and acceptable right side R2 latencies of the blink reflex and poor clinical recovery measured by the House-Brackmann grade of patients with Bell’s palsy showed a statistically significant correlation (p = 0.009). Likewise, in patients with an ENoG degeneration ratio less than 90%, Acceptable left side R1, R2 and abnormal right side R2 latencies or abnormal left side R1, R2 and acceptable right side R2 latencies of the blink reflex and poor clinical recovery from Bell’s palsy showed statistical significance (p = 0.015). Conclusions Blink reflex could be a prognostic factor for clinical recovery in patients with Bell’s palsy. Furthermore, blink reflex could complement the limitations of ENoG as a prognostic test.
Abstract
Objective To determine whether blink reflex can be used as a prognosis test for Bell’s palsy and whether it can complement the limitations of electroneurography (ENoG) as a prognostic test for Bell’s palsy. Methods This retrospective study included 99 patients diagnosed with Bell’s palsy from August 2011 to January 2017. Findings of clinical examination of facial nerve function were recorded using the House-Brackmann scale at the initial visit and follow up examination was done at the second and third visit. Electrophysiological evaluations were performed using blink reflex and ENoG tests within one month of Bell’s palsy onset. Clinical data were analyzed using Student’s T- and Chi-square tests. Results Acceptable left side R1, R2 and abnormal right side R2 latencies or abnormal left side R1, R2 and acceptable right side R2 latencies of the blink reflex and poor clinical recovery measured by the House-Brackmann grade of patients with Bell’s palsy showed a statistically significant correlation (p = 0.009). Likewise, in patients with an ENoG degeneration ratio less than 90%, Acceptable left side R1, R2 and abnormal right side R2 latencies or abnormal left side R1, R2 and acceptable right side R2 latencies of the blink reflex and poor clinical recovery from Bell’s palsy showed statistical significance (p = 0.015). Conclusions Blink reflex could be a prognostic factor for clinical recovery in patients with Bell’s palsy. Furthermore, blink reflex could complement the limitations of ENoG as a prognostic test.
참고문헌 (35)
- Yanagihara N, "Incidence of Bell's palsy", Ann Otol Rhinol Lryngol Suppl, 137, pp.3~4 (1987)
- Hill MD, "The spectrum of electrophysiological abnormalities in Bell's palsy", Can J Neurol Sci, 28, pp.130~133 (2001)[DOI]
- Peitersen E, "Bell's palsy: the spontaneous course of 2,500 peripheral facial nerve palsies of different etiologies", Acta Otolaryngol, 122, pp.4~30 (2002)[DOI]
- Engstrom M, "Prednisolone and valaciclovir in Bell's palsy: a randomised, double-blind, placebocontrolled, multicentre trial", Lancet Neurol, 7, pp.993~1000 (2008)[DOI]
- Nicastri M, "Efficacy of early physical therapy in severe Bell's palsy: a randomized controlled trial", Neurorehabil Neural Repair (2013)
- Sullivan FM, "Early treatment with prednisolone or acyclovir in Bell's palsy", N Engl J Med, 357, pp.1598~1607 (2007)[DOI]
- Gantz BJ, "Surgical management of Bell's palsy", Laryngoscope, 109, pp.1177~1188 (1999)[DOI]
- Sittel C, "Prognostic value of electromyography in acute peripheral facial nerve palsy", Otol Neurotol, 22, pp.100~104 (2001)[DOI]
- Takemoto N, "Prognostic factors of peripheral facial palsy: multivariate analysis followed by receiver operating characteristic and Kaplan-Meier analyses", Otol Neurotol, 32, pp.1031~1036 (2011)[DOI]
- Park JH, "Usefulness of Serial Eelctrophysiologic Tests for Estimating the Prognosis of Bell's Plasy", J Korean EMG Electrodiagn, 10, pp.107~112
- Ghonim M, "Blink reflex: prognostic value in acute peripheral facial palsy", ORL J Otorhinolaryngol Relat Spec, 52, pp.75~79 (1990)[DOI]
- Mizukoshi K, "Prognostic value of blink test in patients with facial paralysis", Acta Otolaryngol, 104, pp.70~75 (1987)
- Kimura J, "Electrophysiological study of Bell palsy: electrically elicited blink reflex in assessment of prognosis", Arch Otolaryngol, 102, pp.140~143 (1976)[DOI]
- Bell C, "On the nerves; giving an account of some experiments on their structure and functions, which lead to a new arrangement of the system", Philos Trans R Soc Lond B Biol Sci, 111, pp.398~424 (1821)[DOI]
- Adour KK, "Herpes simplex virus in idiopathic facial paralysis (Bell palsy)", JAMA, 233, pp.527~530 (1975)[DOI]
- Mulkens P, "Acute facial paralysis: a virological study", Clin Otolaryngol, 5, pp.303~310 (1980)[DOI]
- Murakami S, "Bell palsy and herpes simplex virus: identification of viral DNA in endoneurial fluid and muscle", Ann Intern Med, 124, pp.27~30 (1996)[DOI]
- Sittel C, "Bell's palsy: a 10-year experience with antiphlogistic-rheologic infusion therapy", Otol Neurotol, 21, pp.425~432 (2000)
- Holland NJ, "Recent developments in Bell's palsy", BMJ, 329, pp.553~557 (2004)[DOI]
- Grosheva M, "Prognostic value of electroneurography and electromyography in facial palsy", Laryngoscope, 118, pp.394~397 (2008)[DOI]
- Weiju H, "Surgical treatment of peripheral facial paralysis", J Otol, 7, pp.78~81 (2012)[DOI]
- Marais J, "Repair of the injured facial nerve", Clinical Otolaryngol, 20, pp.387~389 (1995)[DOI]
- Danner CJ, "Facial nerve paralysis", Otolaryngol clin North Am, 41, pp.619~632 (2008)[DOI]
- Dumitru D, "Electrophysiologic evaluation of the facial nerve in Bell's palsy: a review", Am J Phys Med Rehabil, 67, pp.137~144 (1988)[DOI]
- Fisch U, "Prognostic value of electrical tests in acute facial paralysis", Otol Neurotol, 5, pp.494~498 (1984)
- Esslen E, "The acute facial palsies: investigations on the calization and pathogenesis of meato-labyrinthe facial palsies" (1977), Springer
- Heath J, "The neurophysiological investigation of Bell's palsy and the predictive value of the blink reflex", Clinical Otolaryngol, 13, pp.85~92 (1988)[DOI]
- Fisch U, "Surgery for Bell's palsy", Arch Otolaryngol, 107, pp.1~11 (1981)[DOI]
- Grosheva M, "Prognostic value of electroneurography and electromyography in facial palsy", Laryngoscope, 118, pp.394~397 (2008)[DOI]
- Ushio M, "Prediction of the prognosis of Bell's palsy using multivariate analyses", Otol Neurotol, 29, pp.69~72 (2008)[DOI]
- Lee HY, "Effect of aging on the prognosis of Bell's palsy", Otol Neurotol, 34, pp.766~770 (2013)[DOI]
- Riga M, "The role of diabetes mellitus in the clinical presentation and prognosis of Bell palsy", J Am Board Fam Med, 25, pp.819~826 (2012)[DOI]
- Kiziltan ME, "Electrophysiological findings of acute peripheral facial palsy in diabetic and non-diabetic patients", Neurosci Lett, 418, pp.222~226 (2007)[DOI]
- Savadi-Oskouei D, "Independent role of hypertension in Bell's palsy: a case-control study", Eur Neurol, 60, pp.253~257 (2008)[DOI]
- Ilniczky S, "Clinical analysis of patients with peripheral facial palsy", Ideggyogy Sz, 59, pp.400~405 (2006)