한국인에서 불확도를 고려한 척골신경전도검사의 참조 표준치
Ulnar Nerve Conduction Studies: Reference Standards with Extended Uncertainty in Healthy South Korean Adults
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초록
Objective: To develop reference standards for motor and sensory ulnar nerve conduction studies (NCSs) in the South Korean population with a detailed consideration of uncertainty. Methods: Standardized ulnar motor and sensory NCS results from healthy subjects were analyzed. Reference standards of NCSs were produced with uncertainty factors including intra- and inter-observer variability, instrumental variation, distance measurement with a tape ruler, skin surface temperature, and the resolution of NCS machines. We produced a reference value for each parameter with a mean value and expanded uncertainty. Results: Korean reference standards of motor and sensory NCSs for the ulnar nerve were presented with average measured quantities and expanded uncertainties. All NCS measurands except negative spike duration in motor NCS and onset latency in sensory NCS showed a significant main age effect in two-way ANCOVA. Only peak amplitude and negative spike area in motor NCS showed a main sex effect, which was not observed before adjustment for anthropometric factors. No measurands showed interaction effects between age and sex. Conclusion: This study presented reference standards of motor and sensory NCSs for the ulnar nerve with a consideration of uncertainty. These standards are expected to improve the diagnostic reliability for ulnar nerve abnormalities.
Abstract
Objective: To develop reference standards for motor and sensory ulnar nerve conduction studies (NCSs) in the South Korean population with a detailed consideration of uncertainty. Methods: Standardized ulnar motor and sensory NCS results from healthy subjects were analyzed. Reference standards of NCSs were produced with uncertainty factors including intra- and inter-observer variability, instrumental variation, distance measurement with a tape ruler, skin surface temperature, and the resolution of NCS machines. We produced a reference value for each parameter with a mean value and expanded uncertainty. Results: Korean reference standards of motor and sensory NCSs for the ulnar nerve were presented with average measured quantities and expanded uncertainties. All NCS measurands except negative spike duration in motor NCS and onset latency in sensory NCS showed a significant main age effect in two-way ANCOVA. Only peak amplitude and negative spike area in motor NCS showed a main sex effect, which was not observed before adjustment for anthropometric factors. No measurands showed interaction effects between age and sex. Conclusion: This study presented reference standards of motor and sensory NCSs for the ulnar nerve with a consideration of uncertainty. These standards are expected to improve the diagnostic reliability for ulnar nerve abnormalities.
참고문헌 (24)
- Mallik A, "Weir AI : Nerve conduction studies : essentials and pitfalls in practice", J Neurol Neurosurg Psychiatry, 76(Suppl 2), pp.ii23~ii31 (2005)
- Kimura J, "Principles and pitfalls of nerve conduction studies", Ann Neurol, 16, pp.415~429 (1984)
- Stetson DS, "Effects of age, sex, and anthropometric factors on nerve conduction measures", Muscle Nerve, 15, pp.1095~1104 (1992)
- Bolton CF, "The effects of temperature on human compound action potentials", J Neurol Neurosurg Psychiatry, 44, pp.407~413 (1981)
- Halar EM, "Nerve conduction studies in upper extremities : skin temperature corrections", Arch Phys Med Rehabil, 64, pp.412~416 (1983)
- Hennessey WJ, "Median and ulnar nerve conduction studies : normative data for young adults", Arch Phys Med Rehabil, 75, pp.259~264 (1994)
- Falco FJ, "Standardized nerve conduction studies in the upper limb of the healthy elderly", Am J Phys Med Rehabil, 71, pp.263~271 (1992)
- Ginzburg M, "Median and ulnar nerve conduction determinations in the Erb’s point--axilla segment in normal subjects", J Neurol Neurosurg Psychiatry, 41, pp.444~448 (1978)
- Chen S, "Electrodiagnostic reference values for upper and lower limb nerve conduction studies in adult populations", Muscle Nerve, 54, pp.371~377 (2016)
- Dillingham T, "Establishing high-quality reference values for nerve conduction studies : A report from the normative data task force of the American Association of Neuromuscular & Electrodiagnostic Medicine", Muscle Nerve, 54, pp.366~370 (2016)
- JCGM, "JCGM 200:2012: international vocabulary of metrology — basic and general concepts and associated terms (VIM)", Int Organ Stand, ~ (2012)
- JCGM, "JCGM 100:2008: evaluation of measurement data —guide to the expression of uncertainty in measurement", Int Organ Stand, ~ (2008)
- Choi J, "An uncertainty evaluation for multiple measurements by GUM, II", Accred Qual Assur, 8, pp.205~207 (2003)
- 김인중, "An Approach for the Uncertainty Evaluation of the Overall Result from Replications of Measurement: Separately Combining Individual Uncertainty Components According to their ‘systematic’ and ‘random’ Effects", Bulletin of the Korean Chemical Society, 35(4), pp.1057~1060 (2014), 대한화학회[DOI]
- Buschbacher RM, "Ulnar nerve motor conduction to the abductor digiti minimi", Am J Phys Med Rehabil, 78(6 Suppl), pp.S9~S14 (1999)
- Buschbacher RM, "Ulnar 14-cm and 7-cm antidromic sensory studies to the fifth digit: reference values derived from a large population of normal subjects", Am J Phys Med Rehabil, 78(6 Suppl), pp.S63~S68 (1999)
- Letz R, "Covariates of human peripheral nerve function: I. Nerve conduction velocity and amplitude", Neurotoxicol Teratol, 16, pp.95~104 (1994)
- Dumitru D, "Electrodiagnostic medicine" (2002), Hanley & Belfus
- Rivner MH, "Influence of age and height on nerve conduction", Muscle Nerve, 24, pp.1134~1141 (2001)
- Hennessey WJ, "Gender and arm length : influence on nerve conduction parameters in the upper limb", Arch Phys Med Rehabil, 75, pp.265~269 (1994)
- Bolton CF, "Human sensory nerve compound action potential amplitude : variation with sex and finger circumference", J Neurol Neurosurg Psychiatry, 43, pp.925~928 (1980)
- 윤여훈, "한국인의 노인 인구에서 연령에 따른 신경전도검사의 특징", 대한근전도 전기진단의학회지, 13(2), pp.97~102 (2011), 대한근전도전기진단의학회[DOI]
- Robinson LR, "Influences of height and gender on normal nerve conduction studies", Arch Phys Med Rehabil, 74, pp.1134~1138 (1993)
- Kommalage M, "Influence of age, gender, and sidedness on ulnar nerve conduction", J Clin Neurophysiol, 30, pp.98~101 (2013)