손목 터널 증후군에서 하이드록소코발라민 근주 효과: 무작위 대조 연구
Effect of Intramuscular Hydroxocobalamin for Carpal Tunnel Syndrome: Randomized Controlled Trial
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Objectives: To evaluate the effect of intramuscular administration of hydroxocobalamine for the carpal tunnel syndrome (CTS) on clinical symptoms and electrophysiologic changes. Subjects and Methods: 16 CTS patients were randomly assigned to hydroxocobalamine (HC) or sham group. HC group received intramuscular hydroxocobalamine (5 mg) 10 times for 20 days. Tinel score, Phalen time, Levin Questionnaire and nerve conduction study were measured 1 month after injection schedule. All patients were treated with ultrasound during trial period. Results: Total six patients (three in each group) completed follow-up. After one month, Tinel score, Phalen time, Levin Questionnaire and nerve conduction study showed no significant difference between two groups. Conclusion: Intramuscular hydroxocobalamin did not have beneficial effect on CTS for 1 month followup period. However, further data should be collected to conclude the effect of hydroxocobalamin on CTS.
Abstract
Objectives: To evaluate the effect of intramuscular administration of hydroxocobalamine for the carpal tunnel syndrome (CTS) on clinical symptoms and electrophysiologic changes. Subjects and Methods: 16 CTS patients were randomly assigned to hydroxocobalamine (HC) or sham group. HC group received intramuscular hydroxocobalamine (5 mg) 10 times for 20 days. Tinel score, Phalen time, Levin Questionnaire and nerve conduction study were measured 1 month after injection schedule. All patients were treated with ultrasound during trial period. Results: Total six patients (three in each group) completed follow-up. After one month, Tinel score, Phalen time, Levin Questionnaire and nerve conduction study showed no significant difference between two groups. Conclusion: Intramuscular hydroxocobalamin did not have beneficial effect on CTS for 1 month followup period. However, further data should be collected to conclude the effect of hydroxocobalamin on CTS.
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