경두개 자기자극과 확산텐서 신경섬유로 검사를 통한 대뇌 병변의 국소화: 증례보고
Localization of Bilateral Hemisphere Lesion Using Combined Transcranial Magnetic Stimulation and Diffusion Tensor Imaging: Report of Two Cases
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Transcranial magnetic stimulation (TMS) has been a gold standard for investigating central motor pathways in humans. Diffusion tensor imaging with fiber tractography (DTI FT) is known for its usefulness in detecting white matter lesion in vivo. We investigated the clinical usefulness of elucidating the integrity and continuity of corticospinal tract (CST) by combined use of TMS and DTI FT in this study. We report two cases who have presented with left hemiparesis and evaluated by both TMS and DTI FT; 10-year-old boy with Mitochondrial Encephalomyopathy with Lactic Acidosis and Stroke-like episode syndrome and 20-year-old woman with traumatic brain injury. Combined use of TMS and DTI FT successfully led to localize the brain lesion that might cause motor impairment in patients with abnormal signal intensities in MRI. The results of this study suggest that TMS and DTI FT might provide the detailed information between function and anatomy of the CST, complementarily.
Abstract
Transcranial magnetic stimulation (TMS) has been a gold standard for investigating central motor pathways in humans. Diffusion tensor imaging with fiber tractography (DTI FT) is known for its usefulness in detecting white matter lesion in vivo. We investigated the clinical usefulness of elucidating the integrity and continuity of corticospinal tract (CST) by combined use of TMS and DTI FT in this study. We report two cases who have presented with left hemiparesis and evaluated by both TMS and DTI FT; 10-year-old boy with Mitochondrial Encephalomyopathy with Lactic Acidosis and Stroke-like episode syndrome and 20-year-old woman with traumatic brain injury. Combined use of TMS and DTI FT successfully led to localize the brain lesion that might cause motor impairment in patients with abnormal signal intensities in MRI. The results of this study suggest that TMS and DTI FT might provide the detailed information between function and anatomy of the CST, complementarily.
참고문헌 (17)
- Cincotta M, "Neurophysiology of unimanual motor control and mirror movements", Clinical Neurophysiology, 119, pp.744~762 (2008)
- Assaf Y, "Diffusion tensor imaging(DTI)-based white matter mapping in brain research : a review", Journal of molecular neuroscience, 34, pp.51~61 (2008)
- Jang SH, "Comparison of TMS and DTT for predicting motor outcome in intracerebral hemorrhage", Journal of the neurological sciences, 290, pp.107~111 (2010)
- Kwon YH, "Combined study of transcranial magnetic stimulation and diffusion tensor tractography for prediction of motor outcome in patients with corona radiata infarct", Journal of rehabilitation medicine, 43, pp.430~434 (2011)
- Staudt M, "Two types of ipsilateral reorganization in congenital hemiparesis : a TMS and fMRI study", Brain, 125, pp.2222~2237 (2002)
- Mori S, "Three-dimensional tracking of axonal projections in the brain by magnetic resonance imaging", Annals of Neurology : Official Journal of the American Neurological Association and the Child Neurology Society, 45, pp.265~269 (1999)
- DiMauro S, "Mitochondrial encephalomyopathies", Archives of Neurology, 50, pp.1197~1208 (1993)
- Stinear CM, "Functional potential in chronic stroke patients depends on corticospinal tract integrity", Brain, 130, pp.170~180 (2006)
- Rossini PM, "Non-invasive electrical and magnetic stimulation of the brain, spinal cord and roots: basic principles and procedures for routine clinical application", Electroencephalography and Clin Neurophysiol, 91, pp.79~92 (1994)
- van Kuijk AA, "Predicting hand motor recovery in severe stroke : the role of motor evoked potentials in relation to early clinical assessment", Neurorehabilitation and Neural repair, 23, pp.45~51 (2009)
- Bürgel U, "White matter fiber tracts of the human brain : threedimensional mapping at microscopic resolution, topography and intersubject variability", Neuroimage, 29, pp.1092~1105 (2006)
- Cho S-H, "Motor outcome according to the integrity of the corticospinal tract determined by diffusion tensor tractography in the early stage of corona radiata infarct", Neurosci Lett, 426, pp.123~127 (2007)
- Konishi J, "MR tractography for the evaluation of functional recovery from lenticulostriate infarcts", Neurology, 64, pp.108~113 (2005)
- Yang Q, "Serial study of apparent diffusion coefficient and anisotropy in patients with acute stroke", Stroke, 30, pp.2382~2390 (1999)
- Yoshioka H, "Diffusion tensor tractography predicts motor functional outcome in patients with spontaneous intracerebral hemorrhage", Neurosurgery, 62, pp.97~103 (2008)
- Boelmans K, "Hirayama disease is a pure spinal motor neuron disorder—a combined DTI and transcranial magnetic stimulation study", J Neurol, 260, pp.540~548 (2013)
- Hübers A, "The relationship between TMS measures of functional properties and DTI measures of microstructure of the corticospinal tract", Brain stimulation, 5, pp.297~304 (2012)