뇌출혈 환자에서 피질척수로의 뇌량 연결 섬유와 예후와의 관계
Transcallosal Fibers from Corticospinal Tract in Patients with Cerebral Hemorrage
1
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Objective: To investigate the relationship between the transcallosal fibers (TCFs) from the corticospinal tract (CST) and the motor function of the affected extremities in patients with cerebral hemorrhage, using diffusion tensor image tractography (DTT). Method: 49 patients with cerebral hemorrhage and 38 controls were recruited. DTT was performed using 1.5 T magnetic resonance imaging. The DTT findings were classified into 3 groups according to targeting location: no TCF from the CST (type A), TCF ended in the corpus callosum or connected to the cortex of the opposite hemisphere (type B), and TCF that descending toward the lesion after passing through the corpus callosum (type C). Results: The TCF originated from the CST of the unaffected hemisphere, and the presence of fiber descending toward the lesion after passing through the corpus callosum were significantly more prevalent in the patients who showed the worse motor function. Conclusion: The TCF originated from the unaffected CST toward the lesion in patients with cerebral hemorrhage might play a relevant role in compensating motor deficits in the major corticospinal disruption.
Abstract
Objective: To investigate the relationship between the transcallosal fibers (TCFs) from the corticospinal tract (CST) and the motor function of the affected extremities in patients with cerebral hemorrhage, using diffusion tensor image tractography (DTT). Method: 49 patients with cerebral hemorrhage and 38 controls were recruited. DTT was performed using 1.5 T magnetic resonance imaging. The DTT findings were classified into 3 groups according to targeting location: no TCF from the CST (type A), TCF ended in the corpus callosum or connected to the cortex of the opposite hemisphere (type B), and TCF that descending toward the lesion after passing through the corpus callosum (type C). Results: The TCF originated from the CST of the unaffected hemisphere, and the presence of fiber descending toward the lesion after passing through the corpus callosum were significantly more prevalent in the patients who showed the worse motor function. Conclusion: The TCF originated from the unaffected CST toward the lesion in patients with cerebral hemorrhage might play a relevant role in compensating motor deficits in the major corticospinal disruption.
참고문헌 (24)
- Calautti C, "Displacement of primary sensorimotor cortex activation after subcortical stroke: a longitudinal PET study with clinical correlation", Neuroimage, 19, pp.1650~1654 (2003)
- Cunha IT, "Performance-based gait tests for acute stroke patients", Am J Phys Med Rehabil, 81, pp.848~856 (2002)
- Marshall RS, "Evolution of cortical activation during recovery from corticospinal tract infarction", Stroke, 31, pp.656~661 (2000)
- Murase N, "Influence of interhemispheric interactions on motor function in chronic stroke", Ann Neurol, 55, pp.400~409 (2004)
- Strens LH, "The ipsilateral human motor cortex can functionally compensate for acute contralateral motor cortex dysfunction", Curr Biol, 13, pp.1201~1205 (2003)
- Trompetto C, "Motor recovery following stroke: a transcranial magnetic stimulation study", Clin Neurophysiol, 111, pp.1860~1867 (2000)
- Newton JM, "fMRI signal decreases in ipsilateral primary motor cortex during unilateral hand movements are related to duration and side of movement", Neuroimage, 24, pp.1080~1087 (2005)
- Ward NS, "Motor system activation after subcortical stroke depends on corticospinal system integrity", Brain, 129, pp.809~819 (2006)
- Hofer S, "Topography of the human corpus callosum revisited--comprehensive fiber tractography using diffusion tensor magnetic resonance imaging", Neuroimage, 32, pp.989~994 (2006)
- Duque J, "Transcallosal inhibition in chronic subcortical stroke", Neuroimage, 28, pp.940~946 (2005)
- Shimizu T, "Motor cortical disinhibition in the unaffected hemisphere after unilateral cortical stroke", Brain, 125, pp.1896~1907 (2002)
- Dougherty RF, "Occipital-callosal pathways in children: validation and atlas development", Ann N Y Acad Sci, 1064, pp.98~112 (2005)
- Demeurisse G, "Motor evaluation in vascular hemiplegia", Eur Neurol, 19, pp.382~389 (1980)
- Fujii Y, "Cortical reorganization in patients with subcortical hemiparesis: neural mechanisms of functional recovery and prognostic implication", J Neurosurg, 98, pp.64~73 (2003)
- Johansen-Berg H, "The role of ipsilateral premotor cortex in hand movement after stroke", Proc Natl Acad Sci, 통권 : 99, pp.14518~14523 (2002)
- Jang SH, "Transcallosal fibers from corticospinal tract in patients with cerebral infarct", Neurorehabilitation, 24, pp.159~164 (2009)
- Ahn YH, "Can stroke patients walk after complete lateral corticospinal tract injury of the affected hemisphere?", Neuroreport, 17, pp.987~990 (2006)
- Gorsler A, "Modulation of motor cortex excitability induced by pinch grip repetition", J Neural Transm, 111, pp.1005~1016 (2004)
- Aramaki Y, "Suppression of the non-dominant motor cortex during bimanual symmetric finger movement: a functional magnetic resonance imaging study", Neuroscience, 141, pp.2147~2153 (2006)
- Cramer SC, "Motor cortex activation is related to force of squeezing", Hum Brain Mapp, 16, pp.197~205 (2002)
- Ghacibeh GA, "Ipsilateral motor activation during unimanual and bimanual motor tasks", Clin Neurophysiol, 118, pp.325~332 (2007)
- Kobayashi M, "Repetitive TMS of the motor cortex improves ipsilateral sequential simple finger movements", Neurology, 62, pp.91~98 (2004)
- Fregni F, "A sham-controlled trial of a 5-day course of repetitive transcranial magnetic stimulation of the unaffected hemisphere in stroke patients", Stroke, 37, pp.2115~2122 (2006)
- Mansur CG, "A sham stimulation-controlled trial of rTMS of the unaffected hemisphere in stroke patients", Neurology, 64, pp.1802~1804 (2005)