16S rRNA Sequencing으로 동정된 Leuconostoc lactis 균혈증 1예
A Case of Bacteremia Caused by Leuconostoc lactis Identified by 16S rRNA Sequencing
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초록
Leuconostoc은 예전에는 인체 감염이 흔하지 않았으나, 면역력이 저하된 환자에서 균혈증을 포함한 감염을 일으키는 것으로 보고되고 있다. Leuconostoc은 여러 가지 생화학적 시험 결과가 lactobacilli, streptococci, pediococci, enterococci와 공통되는 점들이 있어 오인될 수 있다. Leuconostoc 균종의 특징은 vancomycin 내성을 보이는 것이며 이에 저자들은 vancomycin 내성을 보인 그람양성 구균에 대해 일반적인 kit로는 동정이 안 되었으나 16S rRNA sequencing으로 Leuconostoc lactis로 동정된 1예를 경험하였기에 보고하는 바이다.
Abstract
Leuconostoc spp. used to be considered nonpathogens to human, but human infections have been reported including bacteremia in compromized patients. Leuconostoc spp. may be misidentified as lactobacilli, streptococci, pediococci and enterococci due to atypical biochemical tests. Leuconostoc spp. are intrinsically resistant to vancomycin. We report a case of bacteremia caused by Leuconostoc lactis identified by 16S rRNA sequencing; the isolate was not identified by commercial kits.
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