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A Fatal Case of Infective Endocarditis Caused by Community-Associated Methicillin-Resistant Staphylococcus aureus ST72 in Korea

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초록

지역사회획득 메티실린내성 황색포도알균(Community-associated methicillin-resistant Staphylococcus aureus, CA-MRSA) 은 지난 10년 전부터 전세계적으로 공중보건에 심각한 위협이 되고 있다. 저자들은 Panton-Valentine leukocidin 독소 유전자가 없으면서 USA 300 클론이 아닌 CA-MRSA에 의한 감염성 심내막염으로 사망한 1예를 경험하였기에 보고하 고자 한다. 본 증례는 국내에서 가장 흔한 CA-MRSA 클론의 하나이면서도 위중한 감염의 원인으로 거의 알려지지 않았던 sequence type 72 클론에 의한 치명적인 감염 증례이다.

Abstract

The advent of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has been a worldwide threat to public health for the past decade. We report a fatal case of infective endocarditis caused by a non-USA300, Panton-Valentine leukocidin toxin-negative CA-MRSA clone. This is a serious case of CA-MRSA infection caused by a sequence type (ST) 72 clone, which is one of the common CA-MRSA clones circulating in Korea where serious CA-MRSA infections have been rare.

참고문헌 (11)

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  10. Tsigrelis C, "Infective endocarditis due to community-associated methicillinresistant Staphylococcus aureus in injection drug users may be associated with Panton-Valentine leukocidin-negative strains", Scand J Infect Dis, 39, pp.299~302 (2007)
  11. Millar BC, "Community-associated MRSA (CA-MRSA): an emerging pathogen in infective endocarditis", J Antimicrob Chemother, 61, pp.1~7 (2008)

관련 논문AI추천

지역사회 관련 메티실린내성 황색포도알균에 의한 균혈증 2예강은정, 김정현, 김태형, 박수진, 신희봉, 전민혁, 정윤석, 추은주대한감염학회 · Infection and Chemotherapy2009 · 제41권 제1호Emergence of Community-Genotype Methicillin-Resistant Staphylococcus aureus in Korean Hospitals: Clinical Characteristics of Nosocomial Infections by Community-Genotype Strain강철인, 김소현, 백경란, 백진영, 송재훈, 이남용, 정두련, 조선영, 주은정, 하영은대한감염학회 · Infection and Chemotherapy2017 · 제49권 제2호Staphylococcus lugdunensis에 의한 감염성 심내막염 1예강호석, 구동회, 김양수, 김영휘, 박현구, 변승운, 우준희, 장항제, 최상호, 최성호대한감염학회 · Infection and Chemotherapy2006 · 제38권 제5호Clinical and Microbiological Characteristics of ST72 Methicillin-Susceptible Staphylococcus aureus : Comparison with ST72 Methicillin-Resistant S. aureusBae Seongman, Chang Euijin, Choi Sang-Ho, Chong Yong Pil, Han Jaijun, Jung Jiwon, Kim Min Jae, Kim Sung-Han, Kim Yang Soo, Lee Sang-Oh대한감염학회 · Infection and Chemotherapy2024 · 제56권 제4호Impact of Community-Onset Methicillin-Resistant Staphylococcus aureus on Staphylococcus aureus Bacteremia in a Central Korea Veterans Health Service Hospital김미나, 김춘관, 배은신, 성흥섭, 장정현, 최윤미대한진단검사의학회 · Annals of Laboratory Medicine2019 · 제39권 제2호국내 환자의 혈액에서 분리된 Panton-Valentine 독소 양성인Staphylococcus aureus김의종, 김재석, 김한성, 박정수, 송원근, 이규만, 조현찬대한진단검사의학회 · Annals of Laboratory Medicine2007 · 제27권 제4호

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