발레수행시 Pyridoxine섭취가 골단백 및 아미노산 대사에 미치는 영향
Effects of pyridoxine supplementation with ballet exercise on bone lipoprotein and amino-acid metabolism
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본 연구는 발레수행시 Pyridoxine의 적정 섭취량과 섭취 기간의 타당성을 골단백 및 아미노산 대사와 연관하여 분석함으로서 발레무용수들에게 추가적인 Pyridoxine섭취의 효용성에 관한 실험적 자료를 제시 하는데 목적을 두었다.본 연구의 대상자들은 14명의 발레전공 여대생으로 실험기간 30일 동안 전원에게 흡연, 음주, 각종 영양제 및 약물 복용을 금지시켰으며 발레 활동은 일주일에 3회-5회 실시하였다. GroupI은 Placebo 2.4㎎, GroupII는 Pyridoxine 1.6㎎, GroupIII는 Pyridoxine 2.4㎎을 섭취하도록 하였으며, Double Blind 방법에 의해 실험이 진행되었다. 본 연구의 분석항목은 Osteocalcin(OS), Calcium(CA), Isoleucine, Leucine, Lysine, Phenylaianine, Methionire, Threonine, Tryptophan, Valine 등을 분석하였다. 자료 분석방법에 있어서 Analysis of Covariance(ANCOVA)를 적용하였고, 유의한 차가 나타난 경우 Multiple Range Test(Scheffe)를 실시하였다. 분석한 결과 발레수행 시의 Pyridoxine섭취가 칼슘 농도에 통계적으로 유의한 차이(p<.05)를 나타났으며, Osteocalcin 및 아미노산 등에 통계적으로 유의한 차이를 나타내지 않았다.종합적으로 본 연구결과는 Pyridoxine섭취가 발레와 같은 신체활동수행에 Ergogenic Aids로서 긍정적인 영향을 미친다는 주장을 지지하고 있지는 않다. 그러나 발레무용수와 영양과의 관계뿐만 아니라 Pyridoxine의 생화학적 대사과정에 관한 불명확한 연구 논제들은 Pyridoxine섭취와 신체활동수행 사이의 상호 작용을 직접적으로 규명할 수 있는 실험 설계 방법 및 기자재들을 사용하여 향후에 긍정적으로 연구되어 질 수 있다. 발레수행 동안 혈장에서 발생하는 피리독설 기질 재분포 구조의 중요성, 골격근에서 Pyridoxine대사 작용에 관여하는 집단특정 프로테아제(GSP)의 역할, 발레동작들이 심혈관 질환에 미치는 보호 효과에서 Pyridoxine 의 관련 가능성 등의 논제들이 향후 연구에서 수반 되어야 한다.
Abstract
The purpopse of this study was to determine the effect of pyridoxine supplementation with ballet exercise on bone lipoprotein and amino-acid metabolism. 14 college female ballet dancers were participated in 30 days study for a double blind and subjects were randomly assigned to one of the three groups, i.e., GroupⅠ(n=4): placebo (2.4mg/day); GroupⅡ(n=5): pyridoxine (1.6mg/day); GroupⅢ(n=5): pyridoxine(2.4mg/day) with ballet exercise 3-5 times per week. Study subjects measured osteocalcin(OS), calcium(CA), isoleucine, leucine, lysine, phenylaianine, methionire, threonine, tryptophan, valine, before and after the treatment. Analysis of Covariance (ANCOVA), Multiple Range Test(Scheffe) were used to determine the statistical significance. There were no group differences in the osteocalcin(OS) and essential amino acids, but calcium were significantly changed(p〈.05). The result of this study does not lend support to the contention that pyridoxine intake has much practical impact on ballet exercise performance as a ergogenic acid. However, it does appear that several significant research topics in pyridoxine biochemistry metabolism as well as ballet dancer and nutrition can be explored profitably in the future using experimental designs involving interaction between pyridoxine status and exercise performance.
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