Fungal infections: rising threats, diagnostic challenges, and the path forward for clinical microbiology laboratories
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초록
Fungal diseases are becoming a growing global health concern, with an estimated annual incidence of6.5 million cases of invasive fungal infections and approximately 3.8 million associated deaths, includingapproximately 2.5 million directly attributable to fungal infections [1]. The World Health Organization, inits first fungal priority pathogen list, identified 19 major fungal pathogens posing considerable public healththreats, with Candida albicans, Candida auris, and Cryptococcus neoformans classified as critical fungalpathogens [2]. Moreover, since the onset of the coronavirus disease 2019 pandemic, the prevalence of fungalpathogen interactions has increased significantly in immunosuppressed patients, with reported mortality ratesexceeding 50% in cases of coinfection [3].
Abstract
Fungal diseases are becoming a growing global health concern, with an estimated annual incidence of6.5 million cases of invasive fungal infections and approximately 3.8 million associated deaths, includingapproximately 2.5 million directly attributable to fungal infections [1]. The World Health Organization, inits first fungal priority pathogen list, identified 19 major fungal pathogens posing considerable public healththreats, with Candida albicans, Candida auris, and Cryptococcus neoformans classified as critical fungalpathogens [2]. Moreover, since the onset of the coronavirus disease 2019 pandemic, the prevalence of fungalpathogen interactions has increased significantly in immunosuppressed patients, with reported mortality ratesexceeding 50% in cases of coinfection [3].
참고문헌 (7)
- Denning DW, "Global incidence and mortality of severe fungal disease", Lancet Infect Dis, 24, pp.e428~38 (2024)
- "WHO fungal priority pathogens list to guide research, development and public health action 2022"[URL]
- Silva LN, "Fungal infections in COVID-19-positive patients : a lack of optimal treatment options", Curr Top Med Chem, 20, pp.1951~1957 (2020)
- Kim J, "Fungal identification based on the polyphasic approach : a clinical practice guideline", Ann Clin Microbiol, 27, pp.221~230 (2024)
- Kwon YJ, "Candida and candidemia in Korea", Ann Clin Microbiol, 27, pp.231~244 (2024)
- Won EJ, "Current nonculture-based diagnosis of candidemia", Ann Clin Microbiol, 27, pp.245~255 (2024)
- Kim MH, "Current epidemiology and implication for microbiological diagnosis of cryptococcal infections in Korea", Ann Clin Microbiol, 27, pp.257~265 (2024)