닥스훈트의 원발성 비장 혈관주위세포종 증례
Primary splenic hemangiopericytoma in a dachshund dog
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A 7-year-old, castrated male dachshund dog with tumor of the spleen portion was referred to the Kangwon National University. The tumor removed surgically and tumor size was 6∼7 cm. Histopathologically, this neoplasm was the presence of perivascular whorls of fusiform cells. The cells also arranged in interlacing bundles or storiform patterns. And this neoplasm consisted of spindle cells that often formed distinct whorls around a central capillary. Immunohistochemical analysis revealed multifocally immunoreactivity for a-smooth muscle actin, whereas not immunoreactive for desmin, S-100, von Willebrand factor. On the base of the histological and immunohistochemical results, this neoplasm was diagnosed as a canine hemangiopericytoma.
Abstract
A 7-year-old, castrated male dachshund dog with tumor of the spleen portion was referred to the Kangwon National University. The tumor removed surgically and tumor size was 6∼7 cm. Histopathologically, this neoplasm was the presence of perivascular whorls of fusiform cells. The cells also arranged in interlacing bundles or storiform patterns. And this neoplasm consisted of spindle cells that often formed distinct whorls around a central capillary. Immunohistochemical analysis revealed multifocally immunoreactivity for a-smooth muscle actin, whereas not immunoreactive for desmin, S-100, von Willebrand factor. On the base of the histological and immunohistochemical results, this neoplasm was diagnosed as a canine hemangiopericytoma.
참고문헌 (18)
- Arumugam T., "S100P: a novel therapeutic target for cancer", Amino Acids, 41, pp.893~899 (2011)
- Bostock DE., "Neoplasms of the skin and subcutaneous tissues in dogs and cats", Br Vet J, 142, pp.1~19 (1986)
- Bostock DE., "Prognosis after surgical excision of canine fibrous connective tissue sarcomas", Vet Pathol, 17, pp.581~588 (1980)
- Chijiwa K., "Immunohistochemical evaluation of canine peripheral nerve sheath tumors and other soft tissue sarcomas", Vet Pathol, 41, pp.307~318 (2004)
- Evans SM., "Canine hemangiopericytoma: a retrospective analysis of response to surgery and orthovoltage radia tion", Vet Radiol, 28, pp.13~16 (1987)
- Goebel HH., "Progress in desmin-related myopathies", J Child Neurol, 15, pp.565~572 (2000)
- Goldschmidt MH., "Tumor of the skin and soft tissue, In Tumors in domestic animals, In Tumors in domestic animals. 4th ed", pp.45~118 (2002), Blackwell
- Graves GM., "Canine hemangiopericytoma:23 cases (1967-1984)", J Am Vet Med Assoc, 192, pp.99~102 (1998)
- Hilmas DE., "Radiotherapy of spontaneous fibrous connective-tissue sarcomas in animals", J Natl Cancer Inst, 56, pp.365~368 (1976)
- Kuntz CA., "Prognostic factors for surgical treatment of soft-tissue sarcomas in dogs: 75 cases (1986- 1996)", J Am Vet Med Assoc, 211, pp.1147~1151 (1997)
- Madevell BR., "Tumors of the skin and subcutaneous tissues. Part III. Skin tumors of mesenchymal origin, In Veterinary cancer medicine. 2nd ed", pp.282~325 (1987), Lea & Febiger
- Mazzei M., "Hemangiopericytoma: histological spectrum, immunohistochemical characterization and prognosis", Vet Dermatol, 13, pp.15~21 (2002)
- Pérez J., "Immunohistochemical characterization of hemangiopericytomas and other spindle cell tumors in dog", Vet Pathol, 33, pp.391~397 (1996)
- Richardson RC., "Metastatic canine hemangiopericytoma", J Am VetMed Assoc, 182, pp.705~706 (1983)
- Rizeq MN., "A comparative immunohistochemical study of uterine smooth muscle neoplasms with emphasis on the epithelioid variant", Hum Pathol, 25, pp.671~677 (1994)
- Rodeghiero F., "von Willebrand disease: still an intriguing disorder in the era of molecular medicine", Haemophilia, 8, pp.292~300 (2002)
- Skalli O., "Cytoskeletal remodeling of rat aortic smooth muscle cells in vitro: relationships to cubtune conditions and analogies to in vivo situations", J Submicnosc Cytol, 18, pp.481~493 (1986)
- Yager JA., "Color atlas and text of surgical pathology of the dog and cat: dermatopathology and skin tumors. vol 1" (1994), Wolfe Publishing Ltd
