대본청 앵무(Psittacula eupatria)로부터 PCR에 의한 avian polyomavirus 최초 검출
First detection of avian polyomavirus by PCR from Alexandrine Parakeet (Psittacula eupatria) in Korea
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초록
In early April 2014, a month-old Alexandrine Paraqeet (Psittacula eupatria) that was raised in a domes-tic aviary located in Gyungju-si, Korea was suddenly died and submitted to Animal Disease Intervention Center, Kyungpook National University in order to diagnose the causative agent. In post-mortem exami-nation, the bird had abnormally developed feathers on the neck and abdomen region and subcutaneous hemorrhages on the neck and cheek adjacent to the beak. At necropsy, the bird had hemorrhage on the muscle of the femoral region, ascites, multi-focal hemorrhages on the epicardium, and diffuse hemor-rhages on the sub-serosa of proventriculus and gizzard, suggesting typical avian polyomavirus (APV) infection. The partial large tumor (T) antigen gene of APV was detected by PCR from tissues of the heart, lung, liver, kidney, proventriculus and feathers of the APV-suspected birds. However, other patho-genic virus-specific nucleic acid common with psittacine birds such as avian bornavirus, psittacine beak and feather disease virus and psittacid herpesvirus were not detected from the mixed tissue samples of the bird, indicating this case is due to single infection of APV. Nucleotide sequence analysis of the partially amplified large T antigen DNA was confirmed to have 99∼100% homology with that of the previously reported APV strains. This case report describes the first detection of APV in Alexandrine Paraqeet in Korea.
Abstract
In early April 2014, a month-old Alexandrine Paraqeet (Psittacula eupatria) that was raised in a domes-tic aviary located in Gyungju-si, Korea was suddenly died and submitted to Animal Disease Intervention Center, Kyungpook National University in order to diagnose the causative agent. In post-mortem exami-nation, the bird had abnormally developed feathers on the neck and abdomen region and subcutaneous hemorrhages on the neck and cheek adjacent to the beak. At necropsy, the bird had hemorrhage on the muscle of the femoral region, ascites, multi-focal hemorrhages on the epicardium, and diffuse hemor-rhages on the sub-serosa of proventriculus and gizzard, suggesting typical avian polyomavirus (APV) infection. The partial large tumor (T) antigen gene of APV was detected by PCR from tissues of the heart, lung, liver, kidney, proventriculus and feathers of the APV-suspected birds. However, other patho-genic virus-specific nucleic acid common with psittacine birds such as avian bornavirus, psittacine beak and feather disease virus and psittacid herpesvirus were not detected from the mixed tissue samples of the bird, indicating this case is due to single infection of APV. Nucleotide sequence analysis of the partially amplified large T antigen DNA was confirmed to have 99∼100% homology with that of the previously reported APV strains. This case report describes the first detection of APV in Alexandrine Paraqeet in Korea.
참고문헌 (24)
- Bernier G, "A generalized inclusion body disease in the budgerigar(Melopsittacus undulatus)caused by a papova-like agent", Avian Dis, 25, pp.1083~1092 (1981)
- Bemier G, "Papovavirus induced feather abnormalities and skin lesions in the budgerigar : clinical and pathological findings", Can Vet J, 25, pp.307~310 (1984)
- Bert E, "Detection of beak and feather disease virus(BFDV)and avian polyomavirus(APV)DNA in psittacine birds in Italy", J Vet Med B, 52, pp.64~68 (2005)
- Bozemann LH, "Characterisation of a papovavirus isolated from fledgling budgerigars", Avian Dis, 25, pp.972~980 (1981)
- Davis RB, "A viral disease of fledgling budgerigars", Avian Dis, 25, pp.179~183 (1981)
- Enders FM, "Fatal avian polyomavirus infection during quarantine in adult wild-caught red-faced lovebirds(Agapornis pullaria)", Avian Dis, 41, pp.496~498 (1997)
- Gardner SD, "Characterization of a new polyomavirus(Polyomavirus papionis-2)isolated from baboon kidney cell cultures", Arch Virol, 105, pp.223~233 (1989)
- Guo J, "Widespread avian bornavirus infection in mute swans in the Northeast United States", Vet Med Res Rep, 3, pp.49~52 (2012)
- Hou J, "Virus taxonomy. Eighth Report of the ICTV", pp.231~238 (2005), Elsevier Academic Press
- Johne R, "Agnoprotein 1a and agnoprotein 1b of avian polyomavirus are apoptotic inducers", J Gen Virol, 81, pp.1183~1190 (2000)
- Johne R, "Avian polyomavirus in wild birds : genome analysis of isolates from Falconiformes and Psittaciformes", Arch Virol, 143, pp.1501~1512 (1998)
- Johne R, "The genome of goose hemorrhagic polyomavirus, a new member of the proposed subgenus Avipolyomavirus", Virology, 308, pp.291~302 (2003)
- Kaleta EF, "Investigations on the viral aetiology of a disease of budgerigars(Melopsittacus undulatus)with hepatitis and feather disorders", J Vet Med B, 31, pp.219~224 (1984)
- Katoh H, "Molecular characterization of avian polyomavirus isolated from psittacine birds based on the whole genome sequence analysis", Vet Microbiol, 138, pp.69~77 (2009)
- Krautwald ME, "Polyomavirus infection in budgerigars(Melopsittacus undulatus) : clinical and aetiological studies", J Vet Med B, 36, pp.459~467 (1989)
- Ogawa H, "A survey of avian polyomavirus(APV)infection in imported and domestic bred psittacine birds in Japan", J Vet Med Sci, 68, pp.743~745 (2006)
- Phalen DN, "Infectious diseases of wild animal", pp.206~215 (2007), Blackwell Publishing
- Phalen DN, "Polymerase chain-reaction assay for avian polyomavirus", J Clin Microbiol, 29, pp.1030~1037 (1991)
- Phalen DN, "Organ distribution of avian polyomavirus DNA and virus neutralizing antibody-titres in healthy adult budgerigars", Am J Vet Res, 54, pp.2040~2047 (1993)
- Rahaus M, "A survey to detect subclinical polyomavirus infections of captive psittacine birds in Germany", Vet Microbiol, 105, pp.73~76 (2005)
- Rossi G, "Outbreak of avian polyomavirus infection with high mortality in recently captured Crimson's seedcrackers(Pyrenestes sanguineus)", J Wildl Dis, 41, pp.236~240 (2005)
- Tomaszewski E, "Detection and heterogeneity of Herpesviruses causing Pacheco’ disease in parrots", J Clin Microbiol, 39, pp.533~538 (2001)
- Ypelaar IM, "A universal polymerase chain reaction for the detection of psittacine beak and feather disease virus", Vet Microbiol, 68, pp.141~148 (1999)
- Zhuang Q, "Prevalence and genetic characterization of avian polyomavirus and psittacine beak and feather disease virus isolated from budgerigars in Mainland China", Arch Virol, 157, pp.53~61 (2012)