본문 바로가기
KERD
논문KCI 등재

개와 고양이에서 분리한 Pseudomonas aeruginosa의 항생제 내성

Antimicrobial resistance of Pseudomonas aeruginosa isolated from dogs and cats

1

조회

0

다운로드

0

인용

0

참고문헌

키워드

주제분류수의학

초록

The aim of this study was to investigate the antimicrobial resistance among Pseudomonas (P.) aeruginosa isolated from dogs and cats. A total of 45 (6.2%) P. aeruginosa was isolated from 710 dogs and 21 cats with clinical signs. Resistance to one or more of the antimicrobials tested was observed in 26 (57.8%) P. aeruginosa. Resistance to cefepime was the most frequent (44.4%), followed by ofloxacin (22.2%), levofloxacin (17.8%), norfloxacin (8.9%), ciprofloxacin (6.7%), ceftazidime, aztreonam, colistin, polymixin B and gentamicin (4.4%, respectively), while resistance to piperacillin/tazobactam, imipenem, tobramycin and amikacin was 2.2%, respectively. All isolates were susceptibility to doripenem and meropenem. Antimicrobial susceptibility testing should be a crucial step in selection of appropriate antimicrobial therapy in veterinary medicine. Also, the prudent use of antimicrobials and continuous monitoring for companion animals are required.

Abstract

The aim of this study was to investigate the antimicrobial resistance among Pseudomonas (P.) aeruginosa isolated from dogs and cats. A total of 45 (6.2%) P. aeruginosa was isolated from 710 dogs and 21 cats with clinical signs. Resistance to one or more of the antimicrobials tested was observed in 26 (57.8%) P. aeruginosa. Resistance to cefepime was the most frequent (44.4%), followed by ofloxacin (22.2%), levofloxacin (17.8%), norfloxacin (8.9%), ciprofloxacin (6.7%), ceftazidime, aztreonam, colistin, polymixin B and gentamicin (4.4%, respectively), while resistance to piperacillin/tazobactam, imipenem, tobramycin and amikacin was 2.2%, respectively. All isolates were susceptibility to doripenem and meropenem. Antimicrobial susceptibility testing should be a crucial step in selection of appropriate antimicrobial therapy in veterinary medicine. Also, the prudent use of antimicrobials and continuous monitoring for companion animals are required.

참고문헌 (28)

  1. 축산분야(반려동물 포함)항생제 내성 관리 계획, "농림축산식품부", ~ (2016)
  2. Arais LR, "Antimicrobial resistance, integron carriage, and gyrA and gyrB mutations in Pseudomonas aeruginosa isolated from dogs with otitis externa and pyoderma in Brazil", Vet Dermatol, 27, pp.113~117 (2016)
  3. Bourély C, "Antimicrobial resistance patterns of bacteria isolated from dogs with otitis", Vet Microbiol, 235, pp.280~284 (2019)
  4. Chamberland S, "Antibiotic susceptibility profiles of 941 gram-negative bacteria isolated from septicemic patients throughout Canada. The canadian study group", Clin Infect Dis, 15, pp.615~628 (1992)
  5. Chastre J, "Problem pathogens(Pseudomonas aeruginosa and Acinetobacter)", Semin Respir Infect, 15, pp.287~298 (2000)
  6. 조재근, "개와 고양이에서 분리된 Enterobacteriaceae와 Pseudomonas aeruginosa의", 한국동물위생학회지, 36(3), pp.171~180 (2013), 한국동물위생학회
  7. CLSI, "Performance standards for antimicrobial susceptibility testing;27th ed", CLSI supplement M100, ~ (2017)
  8. Eliasi UL, "Antimicrobial resistance patterns of Pseudomonas aeruginosa isolated from canine clinical cases at a veterinary academic hospital in South Africa", J S Afr Vet Assoc, 22, pp.e1~e6 (2020)
  9. Giguere S, "Antimicrobial Therapy in Veterinary Medicine" (2013), Wiley Blackwell
  10. Harada K, "Characterization of Pseudomonas aeruginosa isolates from dogs and cats in Japan : current status of antimicrobial resistance and prevailing resistance mechanisms", Microbiol Immunol, 56, pp.123~127 (2012)
  11. Hariharan H, "Update on antimicrobial susceptibilities of bacterial isolates from canine and feline otitis externa", Can Vet J, 47, pp.253~255 (2006)
  12. Lin D, "Characterization of antimicrobial resistance of Pseudomonas aeruginosa isolated from canine infections", J Appl Microbiol, 113, pp.16~23 (2012)
  13. Linder JA, "Fluoroquinolone prescribing in the United States : 1995 to 2002", Am J Med, 118, pp.259~268 (2005)
  14. Livermore DM, "Interpretative reading: recognizing the unusual and inferring resistance mechanisms from resistance phenotypes", J Antimicrob Chemother, 48(Suppl. S1), pp.87~102 (2001)
  15. Markey BF, "Clinical veterinary microbiology", pp.275~284 (2013), Mosby Elsevier
  16. Martín Barrasa JL, "Antibacterial susceptibility patterns of Pseudomonas strains isolated from chronic canine otitis externa", J Am Anim Hosp Assoc, 43, pp.307~312 (2000)
  17. Mekić S, "Antimicrobial susceptibility of Pseudomonas aeruginosa isolates from dogs with otitis externa", Vet Rec, 169, pp.125~ (2011)
  18. Normand EH, "Trends of antimicrobial resistance in bacterial isolates from a small animal referral hospital", Vet Rec, 146, pp.151~155 (2000)
  19. 박소영, "Identification and Antimicrobial Susceptibility of Bacteria Isolated from Dogs with Chronic Otitis Externa", 한국임상수의학회지, 34(1), pp.23~26 (2017), 한국임상수의학회[DOI]
  20. Park YJ, "Antimicrobial resistance and novel mutations detected in the gyrA and parC genes of Pseudomonas aeruginosa strains isolated from companion dogs", BMC Vet Res, 16, pp.111~ (2020)
  21. Pedersen K, "Occurrence of antimicrobial resistance in bacteria from diagnostic samples from dogs", J Antimicrob Chemother, 60, pp.775~781 (2007)
  22. Perez F, "Global challenger of multidrug-resistant Acinetobacter baumannii", Antimicrob Agents Chemother, 51, pp.3471~3484 (2007)
  23. Petersen AD, "Frequency of isolation and antimicrobial susceptibility patterns of Staphylococcus intermedius and Pseudomonas aeruginosa isolates from canine skin and ear samples over a 6-year period(1992-1997)", J Am Anim Hosp Assoc, 38, pp.407~413 (2002)
  24. Pintarić S, "Fluoroquinolone susceptibility in Pseudomonas aeruginosa isolates from dogs-comparing disk diffusion and microdilution methods", Veterinarski Arhiv, 87, pp.291~300 (2017)
  25. Rubin J, "Antimicrobial resistance and genetic characterization of fluoroquinolone resistance of Pseudomonas aeruginosa isolated from canine infections", Vet Microbiol, 131, pp.164~172 (2008)
  26. Seol B, "In Vitro Antimicrobial Susceptibility of 183 Pseudomonas aeruginosa strains isolated from dogs to selected antipseudomonal agents", J Vet Med B Infect Dis Vet Public Health, 49, pp.188~192 (2002)
  27. Wildermuth BE, "Susceptibility of Pseudomonas isolates from the ears and skin of dogs to enrofloxacin, marbofloxacin and ciprofloxacin", J Am Anim Hosp Assoc, 43, pp.337~341 (2007)
  28. Yukawa S, "Antimicrobial resistance of Pseudomonas aeruginosa isolated from dogs and cats in primary veterinary hospitals in Japan", Jpn J Infect Dis, 70, pp.461~463 (2017)

관련 논문AI추천

이 간행물의 다른 논문 (7건)