n-Hexane에 의한 삼백초 추출물의 항균 및 항바이러스 활성
Antimicrobial and antiviral activity of Saururus chinensis extract by n-Hexane
0
조회
0
다운로드
4
인용
0
참고문헌
키워드
초록
This study was conducted to investigate the antimicrobial, antivirus properties of Saururus chinensis extracts. The n-hexane extracts from Saururus chinensis showed the active antimicrobial activity against gram-positive bacteria. Minimum inhibitory concentration (MIC) of Saururus chiensis n-hexane extracts was 1.25 mg/ml against B. subtilis and 2.5 mg/ml against S. aureus. The cytotoxicity effects on MDBK (Madin-Darby bovine kidney) cell were observed at the various n-hexane extract concentrations. In TCID50 assay, 0.6 mg/ml of n-hexane extracts decreased BVD (bovine viral diarrhea) virus by 1.4 log, whereas other extracts did not show antiviral activity. In this study, The results suggested that n-hexane extracts and fractions of Saururus chinensis can be a candidate materal of feed additive to chemical antibiotics and antivirus substances.
Abstract
This study was conducted to investigate the antimicrobial, antivirus properties of Saururus chinensis extracts. The n-hexane extracts from Saururus chinensis showed the active antimicrobial activity against gram-positive bacteria. Minimum inhibitory concentration (MIC) of Saururus chiensis n-hexane extracts was 1.25 mg/ml against B. subtilis and 2.5 mg/ml against S. aureus. The cytotoxicity effects on MDBK (Madin-Darby bovine kidney) cell were observed at the various n-hexane extract concentrations. In TCID50 assay, 0.6 mg/ml of n-hexane extracts decreased BVD (bovine viral diarrhea) virus by 1.4 log, whereas other extracts did not show antiviral activity. In this study, The results suggested that n-hexane extracts and fractions of Saururus chinensis can be a candidate materal of feed additive to chemical antibiotics and antivirus substances.
참고문헌 (26)
- 권중안, "속 삼백초와 어성초에 대하여", 대한한약, 3, pp.28~32 (1999)
- 김재길, "천연약물대사전", pp.174~ (1984), 남산당
- 신민교, "임상본초학", pp.336~337 (1994), 영림사
- 이연희, "임상과 축산에서 발견되는 항생제 내성균주의현황", 한국수의공중보건학회, 25, pp.43~54 (2001)
- 축산 항생제내성 및 항생제 사용실태 조사, "정석찬", 식품의약품안전청, ~ (2007)
- 진영화, "질병관리 II-소 바이러스 설사병(Bovine Viral Diahhrea, BVD), 왜 중요한가", 낙농육우회보, 28, pp.136~138 (2008)
- 黃泰康, "常用中藥成分與藥理手冊" (1994), 中國醫藥料 技出版社
- Hierholzer JC, "Virus isolation and quantitation, In Virology Methods Manual. 1st ed.", pp.35~46 (1996), Academy Press
- Jeon GH, "Studies on the mechanism of nitric oxide (NO) induction in the pertoneal macrophages by Herba Saurui (HS)", KOMS, 19, pp.36~49 (1998)
- Jin SW, "Rhizoma Saururi (RS) induced the morphological change of the peritoneal macrophages through nitric oxide (NO)", J of Hebology, 12, pp.131~141 (1997)
- Jung DS, "A study on fatty acids and amino acids of Saururus Chinensis", Cheju Univ Jour (NaturalSci), 35, pp.111~118 (1992)
- Kang SK, "Antimicrobial Activity of Defatted Camellia (Camellia japonica L.) Seeds Extract", J Korean Soc Food Sci Nutr, 27, pp.232~238 (1998)
- 강석남, "항생제 대체를 위한 비타민 E 및 한방부산물을 포함한 허브추출물 및 효소제 복합처리가 거세돈의 혈액콜레스테롤 및 식육의 품질에 미치는 영향", 한국축산식품학회지, 27(1), pp.87~94 (2007), 한국축산식품학회
- 강태윤, "Prevention of Salmonella Infection in Layer Hen Fed with Microbial Fermented Citrus Shell", 생명과학회지, 20(2), pp.190~196 (2010), 한국생명과학회
- 고무석, "삼백초(Saururus chinensis Baill) 추출물의 항균활성", 한국식품영양과학회지, 33(7), pp.1098~1105 (2004), 한국식품영양과학회
- Kott V, "Antiviral activity in Argentine medicinal plants", Journal of Ethnopharmacology, 64, pp.79~84 (1999)
- Kwak JW, "Pharmacological studies on Saururus chinensis Baill", Kyung Hee University Bulletin of Kyung Hee Pharmaceutical Science, 16, pp.137~154 (1988)
- Lee IS, "Effect of water extract from Saururus chinensis (Lour.) Bail water extracts on the cancer cells and antioxidative activity in cytotoxicity", Korean J Postharvest Sci Technol, 8, pp.213~216 (2001)
- 이인선, "삼백초를 첨가한 요구르트의 제조와 품질 특성", 한국식품영양과학회지, 31(3), pp.411~416 (2002), 한국식품영양과학회
- 이상범, "토종 육계에 있어서 복합 생균제 및 면역증강제의 항생제 대체효과", 한국동물자원과학회지, 53(5), pp.409~418 (2011), 한국동물자원과학회
- Park SK, "Studies on the cytotoxic constituent of Saururus chinensis (Lour.) Baill", J Pharm Soc Korea, 41, pp.704~708 (1997)
- 박병성, "국산 적송수피 추출물의 브로일러에 대한 항생제 대체효과", 생명과학회지, 20(7), pp.1047~1053 (2010), 한국생명과학회
- Park JH, "Effects of seed tuber position and number of nodes on growth of Saururus Chinensis Baill", Korean J Medicine Crop Sci, 6, pp.286~293 (1998)
- 박영석, "한약재의 첨가 급여에 따른 콕시듐 억제 효과", 한국가축위생학회지, 35(1), pp.25~31 (2012), 한국가축위생학회
- Seong SH, "Hepatoprotective lignans of Saururus Chinensis", 박사, pp.1998
- Wang EC, "Studies of constituents of Saururus chinensis", Heterocycles, 43, pp.969~976 (1996)