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단삼으로부터 항균물질의 분리

Isolation of Antimicrobial Compounds from Salvia miltiorrhiza Bunge

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Abstract

Bioassay-directed fractionation of the dried roots of Salvia miltiorrhiza led to the isolation of abietane tanshinones, cryptotanshinone and dihydrotanshinone I. Their wtructures were elucidated using 1H-and 13C-NMR, UV, IR and mass spectral analyses. These compounds exhibited a moderate antimicrobial activities against Staphylococcus epidemidis, Staphylococcus aureus, and Staphylococcus pyogene.

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