인삼의 부위별 페놀성 성분 함량 및 멜라닌 생성억제효과
Quantitative Analysis of Phenolic Compounds in Different parts of Panax ginsengC.A. Meyer and Its Inhibitory Effect on Melanin Biosynthesis
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Abstract
Comparison of four phenolic compounds among three different parts of Panax ginseng C.A. Meyer was per-formed in this study. Contents of esculetin, p-coumaric acd, quercetin, maltol in the ethyl acetate fraction were determinatedp-coumaric acid and the leave has a highest concentrationof quercetin and esculetin. This ethyl acetate fraction of the leaves exhibited higher depigmenting activity and lower cell tox-icity than the other parts of ginseng. In addition, it showed that quercetin and esculetin among phenolic compounds highlyinhibited melanin biosynthesis in ginseng. It implies that leaves of ginseng may be used as skin whitening herb. Quercetinand esculetin proved to be active compounds in the leaves of ginseng.