상황버섯, 차가버섯, 느타리버섯 발효식초의 항산화와 항암활성 효과
Antioxidant and Anticancer Effects of Fermentation Vinegars with Phellinus linteus, Inonotus obliquus, and Pleurotus ostreatus
2
조회
0
다운로드
23
인용
0
참고문헌
키워드
초록
The antioxidant and anticancer activities of Phellinus linteus, Inonotus obliquus, and Pleurotus ostreatus according to extraction methods were measured. The contents of polyphenolic compounds were higher in fermented extracts than those in water extracts. The contents were 192.4㎎/100 ㎖ for Inonotus obliquus vinegar, 186.9 ㎎/100 ㎖ for Phellinus linteus vinegar, and 156.5 ㎎/100 ㎖ for Pleurotus ostreatus vinegar, respectively. EDA(electron donating ability) in Phellinus linteus that was highest among mushrooms was 83.9% in the water extract and 96.8% in the fermented extract. The growth of stomach cancer cells, SNU-719 was inhibited 62.4%, 65.5%, and 53.0% by Phellinus linteus vinegar, Inonotus obliquus vinegar, and Pleurotus ostreatus vinegar, respectively and also the growth of liver cancer cells, Hep3B was inhibited 67.1%, 68.3%, and 57.6% by Phellinus linteus vinegar, Inonotus obliquus vinegar, and Pleurotus ostreatus vinegar, while the growth of normal cell, DC2.4 was not affected. Even though Phellinus linteus and Inonotus obliquus showed higher inhibition in cancer cell growth, Pleurotus ostreatus can be efficiently used for antioxidant and anticancer activities due to their cheap price in the market.
Abstract
The antioxidant and anticancer activities of Phellinus linteus, Inonotus obliquus, and Pleurotus ostreatus according to extraction methods were measured. The contents of polyphenolic compounds were higher in fermented extracts than those in water extracts. The contents were 192.4㎎/100 ㎖ for Inonotus obliquus vinegar, 186.9 ㎎/100 ㎖ for Phellinus linteus vinegar, and 156.5 ㎎/100 ㎖ for Pleurotus ostreatus vinegar, respectively. EDA(electron donating ability) in Phellinus linteus that was highest among mushrooms was 83.9% in the water extract and 96.8% in the fermented extract. The growth of stomach cancer cells, SNU-719 was inhibited 62.4%, 65.5%, and 53.0% by Phellinus linteus vinegar, Inonotus obliquus vinegar, and Pleurotus ostreatus vinegar, respectively and also the growth of liver cancer cells, Hep3B was inhibited 67.1%, 68.3%, and 57.6% by Phellinus linteus vinegar, Inonotus obliquus vinegar, and Pleurotus ostreatus vinegar, while the growth of normal cell, DC2.4 was not affected. Even though Phellinus linteus and Inonotus obliquus showed higher inhibition in cancer cell growth, Pleurotus ostreatus can be efficiently used for antioxidant and anticancer activities due to their cheap price in the market.
참고문헌 (22)
- 안미란, "버섯을 첨가한 전통고추장의 품질특성", Journal of the Korean Society for Applied Biological Chemistry, 46(3), pp.229~234 (2003), 한국응용생명화학회
- 안치선, "상황버섯 추출물이 사염화탄소로 간 손상이 유발된 흰쥐에서의 면역조절 효과", 한국약용작물학회지, 17(3), pp.217~222 (2009), 한국약용작물학회
- Blois MS, "Antioxidant determination by the use of a stable free radical", Nature, 26, pp.1198~1202 (1958)
- 변부형, "Raw 264.7 cell에서 차가 버섯 에탄올 추출물이 Cytokine 발현에 미치는 영향", 대한본초학회지, 20(2), pp.55~60 (2005), 대한본초학회
- 서권일, "느타리버섯 김치의 생리활성", 한국식품저장유통학회지, 9(1), pp.56~60 (2002), 한국식품저장유통학회
- 홍희옥, "차가버섯 추출물이 당뇨생쥐 (C57BL", KsJ-m+, 한국영양학회지, pp.2007, 40(7)[DOI]
- 황용주, "차가버섯 추출물이 소화기계 암세포의 증식 및 caspase-3 활성에 미치는 영향", 한국영양학회지, 36(1), pp.18~23 (2003), 한국영양학회
- 정용준, "상황버섯과 발아현미상황버섯 열수추출물의 Murin Macrophage RAW 264.7 세포에서 항염증 반응 비교", 한국약용작물학회지, 17(2), pp.97~101 (2009), 한국약용작물학회
- Jung IC, "Antioxidative effect of fruit body and mycelial extracts of Pleurotus ostreatus", Korean Journal of Food Science and Technology, 28, pp.464~469 (1996)
- 강준용, "상황버섯 추출물 음료의 섭취가 흰쥐의 근육 및 혈액의 대사적 변인에 미치는 영향", Journal of Exercise Nutrition & Biochemistry, 12(1), pp.53~58 (2008), 한국운동영양학회
- Kang TS, "Effect of Pleurotus eryngii on the blood glucose and cholesterol in diabetic rats", The Korean Journal of Mycology, 29, pp.86~90 (2001)
- Kim YS, "Quality of wet noodle prepared with wheat flour and mushroom powder", Korean Journal of Food Science and Technology, 30, pp.1373~1380 (1998)
- 이선미, "국내 시판되는 식초의 항산화 활성", 산업식품공학, 13(3), pp.221~225 (2009), 한국산업식품공학회
- 이영종, "차가버섯 물 추출물의 추출온도에 따른 효능 비교 연구(I)- 산화반응 억제효과-", 대한본초학회지, 22(4), pp.177~185 (2007), 대한본초학회
- 이영종, "차가버섯 물 추출물의 추출온도에 따른 효능 비교 연구(I)- 산화반응 억제효과-", 대한본초학회지, 22(4), pp.177~185 (2007), 대한본초학회
- Park MH, "Anti-cancer activity of Lentinus edoeds and Pleurotus ostreatus", Korean Journal of Food Science and Technology, 30, pp.702~708 (1998)
- 박유경, "Streptozotocin으로 유발한 당뇨쥐에 있어서 차가버섯(Inonotus Obliquus)의 혈당 및 DNA 손상 개선효과", 한국영양학회지, 42(1), pp.5~13 (2009), 한국영양학회
- Rhee YK, "In vitro and in vivo antitumor activity of the fruit body of Phellinus linteus", Korean Journal of Food Science and Technology, 32, pp.477~480 (2000)
- 서훈석, "짚신나물, 삼백초의 항산화와 항암활성 효과", 한국약용작물학회지, 16(3), pp.139~143 (2008), 한국약용작물학회
- 서진희, "상황버섯 복용이 운동선수들의 혈중 면역세포와 사이토카인에 미치는 영향", Journal of Exercise Nutrition & Biochemistry, 11(2), pp.109~116 (2007), 한국운동영양학회
- Slinkard K, "Total phenol analysis:automation and comparison with manual method", American Journal of Enology and Viticulture, 28, pp.49~56 (1977)
- 양병근, "차가버섯 균사체가 Streptozotocin으로 유발된 당뇨 흰쥐의 혈장 포도당과 지질 농도에 미치는 영향", 한국균학회지, 33(2), pp.64~68 (2005), 한국균학회