철쭉 가지 에탄올 추출물 및 용매별 분획물의 항산화 활성과Tyrosinase 저해 활성
Antioxidative Activity and Tyrosinase Inhibition Effect of Ethanol Extract and Its Fractions from the Branch of Rhododendron schlippenbachii
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초록
This study was conducted to investigate the antioxidative activity and tyrosinase inhibitory activity of 50%ethanol extract and its fractions from the branch of Rhododendron schlippenbachii. In DPPH radical scavenging ability,butanol and ethyl acetate fractions showed 59.98% and 55.17% of relative activity compared with positive control (ascorbic acid), but the 50% ethanol extract showed relatively low activity. In nitric oxide (NO) scavenging ability, the ethyl acetate and butanol fractions showed 141.80% and 131.55% relative activity compared with ascorbic acid as used for positive control. On the other hand, tyrosinase inhibitory activity of the ethyl acetate and butanol fractions showed about twice higher activity than positive control (arbutin). It means that the ethyl acetate and butanol fractions from the extract of R. schlippenbachii branch has ability for used as effective radical scavenger and tyrosinase inhibitor.
Abstract
This study was conducted to investigate the antioxidative activity and tyrosinase inhibitory activity of 50%ethanol extract and its fractions from the branch of Rhododendron schlippenbachii. In DPPH radical scavenging ability,butanol and ethyl acetate fractions showed 59.98% and 55.17% of relative activity compared with positive control (ascorbic acid), but the 50% ethanol extract showed relatively low activity. In nitric oxide (NO) scavenging ability, the ethyl acetate and butanol fractions showed 141.80% and 131.55% relative activity compared with ascorbic acid as used for positive control. On the other hand, tyrosinase inhibitory activity of the ethyl acetate and butanol fractions showed about twice higher activity than positive control (arbutin). It means that the ethyl acetate and butanol fractions from the extract of R. schlippenbachii branch has ability for used as effective radical scavenger and tyrosinase inhibitor.
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