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지역별, 연근별 가공백삼의 품질과 지표 성분의 변이

Variation in Content of Marker Compounds and Quality of Processed White Ginseng of Different Cultivation Ages from Different Regions

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Background: The ginsenosides Rb1 (G-Rb1) and Rg1 (G-Rg1) are used as marker compounds, and are the principal bioactive compounds assessed in the quality control of white ginseng. This study was conducted to analyze white ginseng samples of different and to obtain useful data for the quality control of white ginseng. Methods and Results: The variation in the content of G-Rb1 and G-Rg1 was evaluated among 35 samples of 4-, 5-, and 6-year-old white ginseng. The content of both G-Rb1 and G-Rg1 did not significantly differ among ages, and the relative ratio of the maximum to the minimum content of these within ginseng of the same ages was more than two. However, the ratio of G-Rb1 to G-Rg1 content in the 5- and 6-year-old ginseng was significantly higher than that in the 4-year-old one. According to the ‘Ginseng industrial act’, the standard (w/w, %) minimum G-Rg1 and G-Rb1 content is 0.10% and 0.20% or more, respectively. Among the 35 samples examined, the content of G-Rg1 was found to be 0.124 - 0.399% with none being less than the standard level, while that of G-Rb1, was 0.147 - 0.595%, with 4 samples (11.4%) failing to meet the standard levels. The content of G-Rg1 and G-Rb1 did not show a constant relationship with the size of ginseng. Conclusions: In our study, the content of both G-Rg1 and G-Rb1 varied widely, and there was no significant difference among cultivation ages. The results of the present study might provide useful information for the quality control of raw ginseng and processed white ginseng using marker compound.

Abstract

Background: The ginsenosides Rb1 (G-Rb1) and Rg1 (G-Rg1) are used as marker compounds, and are the principal bioactive compounds assessed in the quality control of white ginseng. This study was conducted to analyze white ginseng samples of different and to obtain useful data for the quality control of white ginseng. Methods and Results: The variation in the content of G-Rb1 and G-Rg1 was evaluated among 35 samples of 4-, 5-, and 6-year-old white ginseng. The content of both G-Rb1 and G-Rg1 did not significantly differ among ages, and the relative ratio of the maximum to the minimum content of these within ginseng of the same ages was more than two. However, the ratio of G-Rb1 to G-Rg1 content in the 5- and 6-year-old ginseng was significantly higher than that in the 4-year-old one. According to the ‘Ginseng industrial act’, the standard (w/w, %) minimum G-Rg1 and G-Rb1 content is 0.10% and 0.20% or more, respectively. Among the 35 samples examined, the content of G-Rg1 was found to be 0.124 - 0.399% with none being less than the standard level, while that of G-Rb1, was 0.147 - 0.595%, with 4 samples (11.4%) failing to meet the standard levels. The content of G-Rg1 and G-Rb1 did not show a constant relationship with the size of ginseng. Conclusions: In our study, the content of both G-Rg1 and G-Rb1 varied widely, and there was no significant difference among cultivation ages. The results of the present study might provide useful information for the quality control of raw ginseng and processed white ginseng using marker compound.

참고문헌 (32)

  1. Chen CF, "Comparison of the pharmacological effects of Panax ginseng and Panax quinquefolium", Acta Pharmacologica Sinica, 29, pp.1103~1108 (2008)
  2. 조장원, "Characteristic study on the chemical components of Korean curved ginseng products", Journal of Ginseng Research, 37(3), pp.349~354 (2013), 고려인삼학회[DOI]
  3. 홍희도, "Chemical composition characteristics of Korean straight ginseng products", Journal of Ethnic Foods, 1(1), pp.24~28 (2014), 한국식품연구원
  4. Cho SH, "Saponins of Korean ginseng(Panax ginseng C. A. Meyer: Part 3. Saponin of ginseng by the cultivating locations, sampling season, plant parts, growing stages and the processing", Journal of the Korean society of Agricultural Chemistry and Biotechnology, 20, pp.188~204 (1977)
  5. Choi GY, "A comparative study on standards of ginseng in the pharmacopoeias of Northeast-Asian countries", Korean Herbal Medicine Informatics, 1, pp.53~65 (2013)
  6. Choi KJ, "Components of raw ginseng and quality control", Journal of Ginseng Research, 15, pp.247~256 (1991)
  7. Choi YD, "Effects of compositions of saponin fraction from Korean red ginseng in the relaxation of rabbit and rat corpus cavernosum", Journal of Ginseng Research, 23, pp.13~20 (1999)
  8. Christensen LP, "Simultaneous determination of ginsenosides and polyacetylenes in American ginseng root(Panax quinquefolium L.) by high-performance liquid chromatography", Journal of Agricultural and Food Chemistry, 54, pp.8995~9003 (2006)
  9. Chung IM, "Ginsenosides and phenolics in fresh and processed Korean ginseng(Panax ginseng CA Meyer): Effects of cultivation location, year, and storage period", Food Chemistry, 130, pp.73~83 (2012)
  10. de Souza LR, "Korean red ginseng(Panax ginseng C. A. Meyer) root fractions: Differential effects on postprandial glycemia in healthy individuals", Journal of Ethnopharmacology, 137, pp.245~250 (2011)
  11. 한진수, "직파 4 ~ 6년생 인삼의 연근 및 직경에 따른 Ginsenoside 함량 비교", 한국약용작물학회지, 21(3), pp.184~190 (2013), 한국약용작물학회[DOI]
  12. Harkey MR, "Variability in commercial ginseng products: An analysis of 25 preparations", American Journal of Clinical Nutrition, 73, pp.1101~1106 (2001)
  13. Hong YP, "Development of enhancing effective ingredient and standardization of functional food-materials for brand-name product with ginseng", pp.17~23 (2014)
  14. 황진봉, "국내산 백삼과 태극삼의 크기 및 연근별 인삼사포닌 함량", 한국식품과학회지, 37(3), pp.508~512 (2005), 한국식품과학회
  15. Jang JG, "Study on the changes of saponin contents in relation to root age of Panax ginseng", Korean Journal Food Science Nutrition, 3, pp.37~40 (1983)
  16. Kim MW, "Distribution of saponin in various sections of Panax ginseng root and changes of its contents according to root age", Journal of Ginseng Research, 11, pp.10~16 (1987)
  17. Kim MW, "Saponin contents in various parts of raw red ginseng", Korean Journal of Ginseng Science, 8, pp.8~14 (1984)
  18. Lee CR, "Comparison of ginsenoside composition and contents in fresh ginseng roots cultivated in Korea, Japan, and China at various ages", Korean Journal of Food Science and Technology, 36, pp.847~850 (2004)
  19. 이성우, "인삼의 지하부 생육 및 엑스함량의 경시적 변화", 한국약용작물학회지, 12(6), pp.483~489 (2004), 한국약용작물학회
  20. 李翔國, "인삼 연풍의 근 부위별 직경이 진세노사이드 함량에 미치는 영향", 한국약용작물학회지, 17(6), pp.452~457 (2009), 한국약용작물학회
  21. Enforcement rule of the ginseng industrial act(standards and methods of inspection), "Ministry of Agriculture, Food and Rural Affairs", Government Complex-Sejong, 339~012 (2014)
  22. Ministry of Food and Drug Safety, "Standard and specification of health functional foods - Health functional food test method in notification full text(KFDA Notification No. 2014-204)", Ministry of Food and Drug Safety, 348~351 (2014)
  23. Ministry of Food and Drug Safety, "The Korean herbal pharmacopoeia-Annex 6. VI. Herbal medicine test method of in notification full text(KFDA Notification No. 2017-85)", Ministry of Food and Drug Safety, 130~ (2017)
  24. Ministry of Food and Drug Safety, "The Korean pharmacopoeia-Annex 5. General test method: No. 29. Herbal medicine test method of in notification full text(KFDA Notification No. 2018-16)", Ministry of Food and Drug Safety, 70~ (2018)
  25. 남기열, "흑삼의 화학성분 및 생리활성에 대한 최근 연구", 생약학회지, 46(3), pp.173~188 (2015), 한국생약학회
  26. Nam KY, "Relationship of saponin and non-saponin for the quality of ginseng", Journal of Ginseng Research, 22, pp.274~283 (1998)
  27. Nam KY, "Contemporary Korean ginseng(chemical constituents and pharmacological activity)", pp.13~18 (1996)
  28. Namba TM, "Fundamental studies on the evaluation of the crude drugs. Part 3. Chemical and biological evaluation of ginseng and related crude drugs", Journal of the Pharmaceutical Society of Japan, 94, pp.252~260 (1974)
  29. Samukawa K, "Simultaneous analysis of ginsenosides of various ginseng radix by HPLC", Journal of the Pharmaceutical Society of Japan, 115, pp.241~249 (1995)
  30. Sengupta S, "Modulating angiogenesis: The yin and the yang in ginseng", Circulation, 110, pp.1219~1225 (2004)
  31. Byong-Kyu Shin, "Chemical diversity of ginseng saponins from Panax ginseng", Journal of Ginseng Research, 39(4), pp.287~298 (2015), 고려인삼학회
  32. Vuksan V, "Herbal remedies in the management of diabetes: Lessons learned from the study of ginseng", Nutrition, Metabolism & Cardiovascular Diseases, 15, pp.149~160 (2005)

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