황칠나무 잎의 면역활성증진기능 탐색
Screening of Immune Activation Activities in the Leaves of Dendropanax morbifera Lev.
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Abstract
The immune activation activities of ethanol, ethanol: water(1:1,v/v) and water extracts from Dendropanax morbifera Lev. were compared. The crude extracts showed relatively low cytotoxicity as less than 26% by using human normal liver cell(WRL-68). For example, the ethanol extract inhibited in MCF7 and H데3B cells in adding 1.0 mg/mL ethanol extracts. The growth of human immune T and B cells was enhanced up to 1.22~1.27 times by adding the crude extracts. These are a trend of increasing secretion of cytokines(IL-6, TNF-α) from human B/T cell for 6 day cultivation. It was found that the immune activation activities of the crude extracts seemed to be higher than those obtained by using other solvents.