Synthesis of New Phospholipid Biocompatible Textile Finishing Agent
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Abstract― A methacrylate monomer having phospholipid polar group and cell membrane structure is known as highly biocompatible. Based on these properties, new biocompatible multi-functional textile finishing agent was developed using phospolipid copolymer. 2-Methacryloyloxyethyl phosphorylcholine (MPCE) was synthesized using 2-hydroxyethyl methacrylate (HEMA), 2-chloro-2-oxo-1,3,2-dioxaphospholane (COP) and triethylamine (TEA), and then polymerized to prepare MPCE copolymer by radical polymerization using azobisisobutyronitrile(AIBN). The structures of MPCE was characterized by FT-IR and 1H NMR and will be evaluated as textile finishing agent in further study.
Abstract
Abstract― A methacrylate monomer having phospholipid polar group and cell membrane structure is known as highly biocompatible. Based on these properties, new biocompatible multi-functional textile finishing agent was developed using phospolipid copolymer. 2-Methacryloyloxyethyl phosphorylcholine (MPCE) was synthesized using 2-hydroxyethyl methacrylate (HEMA), 2-chloro-2-oxo-1,3,2-dioxaphospholane (COP) and triethylamine (TEA), and then polymerized to prepare MPCE copolymer by radical polymerization using azobisisobutyronitrile(AIBN). The structures of MPCE was characterized by FT-IR and 1H NMR and will be evaluated as textile finishing agent in further study.
참고문헌 (12)
- J. E. Browne, "Preparation of Phospholipid Analogues using the Phosphoramidite Route", J. Chem. Soc., 1, pp.653~657 (2000)
- S. D. Stamatov, "Synthesis of DL-α- tocopherolligated phospholipids", Chemistry and Physics of Lipids, 91, pp.129~134 (1998)
- K. Ishihara, "Preparation of Phospholipid Polymers and Their Properties as Polymer Hydrogel Membranes", J. Polymer, 20(5), pp.355~360 (1990)
- A. Z. Zhu, "Preparation and Blood Compatibility of Phosphorylcholine- bonded O-butyrylchitosan", Polym. Int, 52, pp.81~85 (2003)
- Y. H. Ma, "Well-Defined Biocompatible Block Copolymers via Atom Transfer Radical Polymerization of 2-Methacryloyloxyethyl Phosphorylcholine in Protic Media", Macromolecules, 36, pp.3475~3484 (2003)
- A. B. Lowe, "Synthesis and Solution Properties of Zwitterionic Polymers", Chem. Rev., 102, pp.4177~4189 (2002)
- A. L. Lewis, "Phosphorylcholine-based Polymers and Their Use in the Prevention of Biofouling", Colloids and Surfaces B, 18, pp.261~275 (2000)
- K. H. Chae, "Anti-fouling Epoxy Coatings for Optical Biosensor Application based on Phosphorylcholine", Sensors and Actuators B, 124, pp.153~160 (2007)
- D. Horak, "The Use of Poly(2-hydroxyethyl methacrylate) in Medicine", Chemicke Listy, 86(9), pp.681~691 (1992)
- T. R. Burrow, "Wound dressings, GB Patent 2288736", ~ (1995)
- X. Z. Zhang, "Effect of Mixed Solvents on Characteristics of Poly(N-isopropylacrylamide gels)", Langmuir, 18, pp.2538~2542 (2002)
- R. A. Stile, "Synthesis and Characterization of Injectable Poly(N-isopropylacrylamide)-based Hydrogels that Support Tissue Formation in Vitro", Macromolecules, 32, pp.7370~7379 (1999)