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Monocyte Chemoattractant Protein-1(MCP-1) -2518 유전자 다형성과 주요 우울장애

Monocyte Chemoattractant Protein-1 (MCP-1) -2518 Polymorphism and Major Depressive Disorder

김정진|이수정|전태연|이지현|이철|김태석|이창욱|신윤경|배치운|백인호
대한신경정신의학회 (Korean Neuropsychiatric Association)|2004.07|신경정신의학 (JOURNAL OF THE KOREAN NEUROPSYCHIATRIC ASSOCIATION)|제43권 제4호|pp. 381-385

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참고문헌

키워드

주요 우울장애 · MCP1 -2518 유전자 다형성 · 한국인.Major depressive disorder·MCP1 -2518 polymorphism·Korean.
주제분류정신과학

초록

Abstract

Object：This study was designed to examine the association between monocyte chemoattractant protein-1 (MCP1) -2518 polymorphism and major depressive disorder (MDD). Methods：Ninety patients with MDD and 114 healthy controls participated in this study. Genotyping was performed by the polymerase chain reaction-restriction fragment length polymorphism method. Results：Genotype and allele distributions in patients with MDD were significantly different from those of the controls. In particular, subjects with the allele A were found to have an increased risk of MDD. Conclusion：The present study suggests that the MCP1 -2518 polymorphism may have a potential role for susceptibility to MDD in the Korean population and thus calls for consecutive studies in order to pile up the data with larger different ethnic background. (J Korean Neuropsychiatr Assoc 2004;43(4):381-385)

참고문헌 (31)

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관련 논문AI추천

양극성 장애와 Monocyte Chemoattractant Protein-1 유전자 다형성이철, 김정진, 김태석, 배치운, 백인호, 이수정, 이창욱, 장우영, 전태연대한신경정신의학회 · 신경정신의학2004 · 제43권 제5호정신분열병과 Monocyte Chemoattractant Protein-1 (MCP-1) 유전자다형성 (-2518A/G)의 연합연구이철, 김정진, 방승규, 배치운, 백인호, 양대현, 유혜숙, 이수정, 이창욱, 정규인대한신경정신의학회 · 신경정신의학2003 · 제42권 제4호G308A tumor necrosis factor - α 유전자 다형성과 주요 우울장애의 연합연구한훈, 김광수, 박원명, 배치운, 오해정, 전태연, 채정호대한신경정신의학회 · 신경정신의학2003 · 제42권 제2호양극성 장애 1형에서 종양괴사인자 베타 유전자 다형성김원, 박원명, 배치운, 우영섭, 이경욱, 전태연, 채정호대한신경정신의학회 · 신경정신의학2005 · 제44권 제6호주요 우울장애에서 Cytotoxic T Lymphocyte Antigen (CTLA-4) 유전자의 다형성한훈, 김광수, 김병균, 박원명, 배치운, 유태열, 전태연, 채정호대한신경정신의학회 · 신경정신의학2001 · 제40권 제5호정신분열병에서 Interleukin-4 시발자와 Interleukin-4 수용체 유전자의 다형성배치운, 이경욱, 전태연, 최진욱대한신경정신의학회 · 신경정신의학2002 · 제41권 제5호

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