본문 바로가기
KERD
논문KCI 등재

저빈도 반복성 경두개 자기자극이 정산인의 시각적 단기 기억에 미치는 영향

Effects of Low Frequency Repetitive Transcranial Magnetic Stimulation on Visual Short Term Memory in Healthy Individuals

2

조회

0

다운로드

0

인용

0

참고문헌

키워드

주제분류정신과학

초록

Abstract

Objectives:Repetitive transcranial magnetic stimulation (rTMS) is a novel, noninvasive method of brain stimulation. Since conventional rTMS does not cause seizure, marked advantage over electroconvulsive therapy (ECT), rTMS can be used easily and widely. Once the effects of rTMS on cognitive function are elucidated, its application will be further extended. However, the effects of rTMS on cognitive function have not been well examined. This study aimed to evaluate the effect of low frequency rTMS on visual short term memory. Methods:Forty normal healthy volunteers were randomly assigned to rTMS (n=20) or sham (n=20) groups. The rTMS group were again randomly divided into left prefrontal (n=10) and right prefrontal (n=10) groups. For each group rTMS was given at 1 Hz for 20 minutes with 100% of motor threshold. As a cognitive task, Corsi Block Tapping Test (CORSI) in the computerized Vienna Test System, which can assess visual short term memory, was performed before, during, and after the rTMS. Results:No significant difference was found in the visual short term memories between the rTMS and the sham groups before, during, or after 1 Hz rTMS, nor between the left and right prefrontal rTMS groups. Conclusion:This study demonstrates that rTMS, contrary to ECT, has no adverse visual short term memory effect when used as the standard treatment paradigm. Therefore, rTMS could be a new and safe treatment method in various neuropsychiatric fields without any interference of cognitive function. (J Korean Neuropsychiatr Assoc 2004;43(5):590-595)

참고문헌 (29)

  1. "Introduction and overview of TMS physics", pp.13~44 (2000), American Psychiatric Press
  2. "Transcranial magnetic stimulation:applications in neuropsychiatry", 56, pp.300~311 (1999)
  3. "Transcranialmagnetic stimulation:a novel antidepressive strategy?", 34, pp.204~207 (1996)
  4. "A randomized clinical trial of repetitive transcranialmagnetic stimulation in the treatment of major depression", 47, pp.332~337 (2000)
  5. "Is TMS an antibipolar treatment?", pp.201~208 (2000), American PsychiatricPress
  6. "Effect of prefrontal repetitive transcranial magneticstimulation in obsessive-compulsive disorder:a preliminary study", 154, pp.867~869 (1997)
  7. "Repetitive transcranial magnetic stimulation forposttraumatic stress disorder", 55, pp.276~279 (1998)
  8. "Pharmacological management of refractorydepression", 34, pp.451~456 (1989)
  9. "Electroconvulsive therapy in general hospital psychiatry:a focus on new indications and technologies", 3, pp.292~296
  10. "Theeffects of electroconvulsive therapy on memory of autobiographicaland public events", 57, pp.581~590 (2000)
  11. "Effects of stimulusparameters on seizure duration and ECS-induced retrograde amnesia", 18, pp.31~37 (2002)
  12. "Lasting cortical activation after repetitive TMS of the motorcortex:a glucose metabolic study", 54, pp.956~963 (2000)
  13. "Depression of motor cortex excitability by low-frequency transcranialmagnetic stimulation", 48, pp.1398~1403 (1997)
  14. "Short-term memory:no evidence of effect of rapid-repetitive transcranial magnetic stimulationin healthy individuals", 240, pp.373~376 (1993)
  15. "Induction of a recall deficit by rapid-rate transcranial magneticstimulation", 5, pp.1157~1160 (1994)
  16. "Induction of errors in a delayed responsetask by repetitive transcranial magnetic stimulation of the dorsolateralperceptional cortex", 5, pp.2517~2520 (1994)
  17. "Short-termmemory performance with magnetic stimulation of the motor cortex", 241, pp.135~138 (1991)
  18. "Verbal working memorycomponents can be selectively influenced by transcranial magneticstimulation in patients with left temporal lobe epilepsy", 34, pp.775~783 (1996)
  19. "Schuhfried Developmentand Production of Scientific Equipment" (1993)
  20. "Lack of adverse cognitive effects of 1Hz and 20 Hzrepetitive transcranial magnetic stimulation at 100% of motor thresholdover left prefrontal cortex in depression", 17, pp.259~263 (2001)
  21. "Impairment of visual perception and visualshort term memory scanning by transcranial magnetic stimulation ofoccipital cortex", 87, pp.421~432 (1991)
  22. "Facilitationof picture naming by focal transcranial magnetic stimulation of Wernicke’sarea", 121, pp.371~378 (1998)
  23. "Repetitive transcranial magnetic stimulation (rTMS) inpharmacotherapy-refractory major depression: comparative study offast, slow and sham rTMS", 86, pp.163~171 (1999)
  24. "Enhancing analogic reasoning with rTMS over the left prefrontalcortex", 56, pp.526~528 (2001)
  25. "Repetitive transcranial magnetic stimulation in thetreatment of medication-resistant depression:preliminary data", 187, pp.114~117 (1999)
  26. "Cognitive effects of 1- and 20-hertz repetitive transcranialmagnetic stimulation in depression:preliminary report", 13, pp.119~124 (2000)
  27. "Does transcranial magnetic magnetic stimulation (TMS) over motoror prefrontal cortex modify tics in patients with Tourette’s syndrome?:a pilot study", pp.110~ (2001)
  28. "저빈도 반복경두개자기자극(rTMS) 의 강박 증상에 대한 효능", pp.138~ (2002)
  29. "Transcranial magnetic stimulation in the treatment of mood disorder:a review and comparison with electroconvulsive therapy", 46, pp.720~727 (2001)

관련 논문AI추천

이 간행물의 다른 논문 (16건)