강박장애와 공황장애 환자의 삶의 질
Quality of Life for Patients with Obsessive-Compulsive Disorder and Panic Disorder
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초록
본 연구는 공황장애 환자와 더불어 국내에서 많은 보고가 없는 강박장애 환자들의 삶의 질을 연구하였다는데 의의가 있다. 본 연구 결과 강박장애와 공황장애 환자의 삶의 질은 정상인에 비해 저하되어 있었으며, 같은 불안장애인 공황장애와 비교할 때도 심리적 영역과 더불어 학업, 직업, 가족생활 기능 저하 등 사회적 관계 영역의 삶의 질 저하가 강박장애 환자에게서 보다 특징적임을 알 수 있었다. 따라서 임상가들은 강박 장애 환자의 치료를 계획함에 있어 사회적 관계 및 심리적 측면의 삶의 질의 개선을 좀 더 고려할 필요가 있을 것이다. 공황장애 환자에서는 우울증상의 정도, 광장공포증의 정도, 공황발작의 빈도 등이 전체적인 삶 의 질을 비롯한 대부분의 하위 영역과 유의한 상관성을 보임을 확인하였다. 강박장애 환자에서 역시 우울증상 정도가 심할수록 삶의 질이 낮았다. 하지만 강박 증상 심각도는 삶의 질과의 연관성을 보이지 않았는데, 이에 대해서는 기존의 연구들에서도 일관된 결과를 보이지 않고 있으며, 대상 환자수, 병식 및 공병 양상에 따른 분류 등을 보완한 추후 연구가 필요할 것이다.
Abstract
Objectives:Aim of this study was to compare quality of life (QOL) in obsessive compulsive disorder (OCD), panic disorder (PD) and healthy controls. Additionally, relationship between clinical factors in patients and their QOL were explored. Methods:49 patients with OCD, 109 patients with PD and 54 healthy controls were recruited. Total scores and scores of each domain of WHO Quality of Life scale (WHOQOL) were compared in the three groups. Correlation analysis and regression analysis were performed to examine the relationship between QOL and the clinical characteristics in the patient group. Results:Total scores and scores of all domains except environmental domain of WHOQOL in patient group were decreased compared to those in healthy control. Scores of social and psychological domains in the OCD group were lower than those in the PD group. The severity of agoraphobia and depression were factors affecting the QOL in the PD group. For the OCD group, comorbid depression was related to social and psychological domain of WHOQOL. Conclusion:QOL in patients with OCD and PD was poorer than that of healthy controls. Social relationships and psychological functioning may be poorer in patients with OCD than patients with PD. The severity of depression and agoraphobia predicted QOL in patients with PD. Comorbid depression in OCD might be a predictor of poor QOL. (J Korean Neuropsychiatr Assoc 2006;45(5):438-443)
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