대기오염이 알레르기비염에 미치는 영향
The impact of air pollution on allergic rhinitis
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초록
Recently, air pollution has become more and more severe globally and has decreased the quality of life significantly in subjects with or without allergic diseases. Air pollution more severely affects patients with allergic diseases, including allergic rhinitis (AR); therefore, it could devastate quality of life. Many epidemiological studies have shown that air pollutants increased outpatient clinic visits as well as the prevalence/severity of AR and decreased quality of life in patients with AR. Traffic-related air pollution also increases the severity and occurrence rate of AR, and heavy traffic is also associated with an increased prevalence of AR. Immunologically, air pollutants increase airway inflammation and mucin production by triggering the generation of reactive oxygen species and inducing the nucleotide-binding domain, leucine-rich repeat protein 3 inflammasome and apoptosis. Since air pollution affects both the upper and lower airways and is known to be a risk factor for AR, proper diagnosis and treatment should be applied. In this review article, we will address several epidemiological and clinical studies about the effects of air pollution on AR, mechanisms by which air pollutants aggravate AR, and treatment of AR triggered by air pollutant.
Abstract
Recently, air pollution has become more and more severe globally and has decreased the quality of life significantly in subjects with or without allergic diseases. Air pollution more severely affects patients with allergic diseases, including allergic rhinitis (AR); therefore, it could devastate quality of life. Many epidemiological studies have shown that air pollutants increased outpatient clinic visits as well as the prevalence/severity of AR and decreased quality of life in patients with AR. Traffic-related air pollution also increases the severity and occurrence rate of AR, and heavy traffic is also associated with an increased prevalence of AR. Immunologically, air pollutants increase airway inflammation and mucin production by triggering the generation of reactive oxygen species and inducing the nucleotide-binding domain, leucine-rich repeat protein 3 inflammasome and apoptosis. Since air pollution affects both the upper and lower airways and is known to be a risk factor for AR, proper diagnosis and treatment should be applied. In this review article, we will address several epidemiological and clinical studies about the effects of air pollution on AR, mechanisms by which air pollutants aggravate AR, and treatment of AR triggered by air pollutant.
참고문헌 (48)
- Dykewicz MS, "Joint Task Force algorithm and annotations for diagnosis and management of rhinitis", Ann Allergy Asthma Immunol, 81, pp.469~473 (1998)
- Keith PK, "The burden of allergic rhinitis(AR)in Canada : perspectives of physicians and patients", Allergy Asthma Clin Immunol, 8, pp.7~ (2012)
- Zou QY, "Exposure to air pollution and risk of prevalence of childhood allergic rhinitis : a meta-analysis", Int J Pediatr Otorhinolaryngol, 112, pp.82~90 (2018)
- "Coronavirus disease (COVID-19) outbreak situation" (2020)[URL]
- "COVID-19 cases in Korea" (2020)[URL]
- Le T, "Unexpected air pollution with marked emission reductions during the COVID-19 outbreak in China", Science, 369, pp.702~706 (2020)
- Berman JD, "Changes in U.S. air pollution during the COVID-19pandemic", Sci Total Environ, 739, pp.139864~ (2020)
- Naclerio R, "International expert consensus on the management of allergic rhinitis(AR)aggravated by air pollutants : impact of air pollution on patients with AR : current knowledge and future strategies", World Allergy Organ J, 13, pp.100106~ (2020)
- Wang Y, "House dust mite allergen levels in households and correlation with allergic rhinitis symptoms", Am J Rhinol Allergy, 28, pp.193~196 (2014)
- Caillaud D, "Indoor mould exposure, asthma and rhinitis: findings from systematic reviews and recent longitudinal studies", Eur Respir Rev, 27, pp.170137~ (2018)
- Kleinstreuer C, "Modeling airflow and particle transport", deposition in pulmonary airways, 2008, pp.163, 128~138
- Wu JZ, "Effects of particulate matter on allergic respiratory diseases", Chronic Dis Transl Med, 4, pp.95~102 (2018)
- Kim BJ, "Association of ozone exposure with asthma, allergic rhinitis, and allergic sensitization", Ann Allergy Asthma Immunol, 107, pp.214~219 (2011)
- 서성철, "GIS-based Association Between PM10 and Allergic Diseases in Seoul: Implications for Health and Environmental Policy", Allergy, Asthma & Immunology Research, 8(1), pp.32~40 (2016), 대한천식알레르기학회
- Cabrera M, "Association between seasonal allergic rhinitis and air pollution, meteorological factors, and grass pollen counts in Madrid(1996 and 2009)", J Investig Allergol Clin Immunol, 29, pp.371~377 (2019)
- Diaz-Sanchez D, "Combined diesel exhaust particulate and ragweed allergen challenge markedly enhances human in vivo nasal ragweed-specific IgE and skews cytokine production to a T helper cell 2-type pattern", J Immunol, 158, pp.2406~2413 (1997)
- Heinrich J, "Improved air quality in reunified Germany and decreases in respiratory symptoms", Epidemiology, 13, pp.394~401 (2002)
- Wouters IM, "Upper airway inflammation and respiratory symptoms in domestic waste collectors", Occup Environ Med, 59, pp.106~112 (2002)
- Zhang F, "Time-series studies on air pollution and daily outpatient visits for allergic rhinitis in Beijing, China", Sci Total Environ, 409, pp.2486~2492 (2011)
- Wang J, "Associations between air pollution and outpatient visits for allergic rhinitis in Xinxiang, China", Environ Sci Pollut Res Int, 27, pp.23565~23574 (2020)
- Penard-Morand C, "Long-term exposure to close-proximity air pollution and asthma and allergies in urban children", Eur Respir J, 36, pp.33~40 (2010)
- Su Ho Jeong, "Comparison of air pollution and the prevalence of allergy-related diseases in Incheon and Jeju City", Clinical and Experimental Pediatrics, 54(12), pp.501~506 (2011), 대한소아청소년과학회
- Cecchi L, "External exposome and allergic respiratory and skin diseases", J Allergy Clin Immunol, 141, pp.846~857 (2018)
- Burte E, "Long-term air pollution exposure is associated with increased severity of rhinitis in 2 European cohorts", J Allergy Clin Immunol, 145, pp.834~842 (2020)
- Bedard A, "Interactions between air pollution and pollen season for rhinitis using mobile technology : a MASK-POLLAR Study", J Allergy Clin Immunol Pract, 8, pp.1063~1073 (2020)
- Bousquet J, "POLLAR : Impact of air POLLution on Asthma and Rhinitis; a European Institute of Innovation and Technology Health(EIT Health)project", Clin Transl Allergy, 8, pp.36~ (2018)
- Min KD, "Association between exposure to traffic-related air pollution and pediatric allergic diseases based on modeled air pollution concentrations and traffic measures in Seoul, Korea : a comparative analysis", Environ Health, 19, pp.6~ (2020)
- 정달영, "Effect of Traffic-Related Air Pollution on Allergic Disease: Results of the Children’s Health and Environmental Research", Allergy, Asthma & Immunology Research, 7(4), pp.359~366 (2015), 대한천식알레르기학회
- Bose S, "Association of traffic air pollution and rhinitis quality of life in Peruvian children with asthma", PLoS One, 13, pp.e0193910~ (2018)
- Fuertes E, "Childhood allergic rhinitis, traffic-related air pollution, and variability in the GSTP1, TNF, TLR2, and TLR4 genes : results from the TAG Study", J Allergy Clin Immunol, 132, pp.342~352 (2013)
- Lindgren A, "Traffic exposure associated with allergic asthma and allergic rhinitis in adults. A cross-sectional study in southern Sweden", Int J Health Geogr, 8, pp.25~ (2009)
- Gao N, "Lung function and systemic inflammation associated with short-term air pollution exposure in chronic obstructive pulmonary disease patients in Beijing, China", Environ Health, 19, pp.12~ (2020)
- Eguiluz-Gracia I, "The need for clean air : the way air pollution and climate change affect allergic rhinitis and asthma", Allergy, 75, pp.2170~2184 (2020)
- Hong Z, "Airborne fine particulate matter induces oxidative stress and inflammation in human nasal epithelial cells", Tohoku J Exp Med, 239, pp.117~125 (2016)
- Cho HY, "Nrf2 protects against airway disorders", Toxicol Appl Pharmacol, 244, pp.43~56 (2010)
- Gilles S, "Pollen exposure weakens innate defense against respiratory viruses", Allergy, 75, pp.576~587 (2020)
- Shusterman DJ, "Subjects with seasonal allergic rhinitis and nonrhinitic subjects react differentially to nasal provocation with chlorine gas", J Allergy Clin Immunol, 101, pp.732~740 (1998)
- Hernandez M, "Airway cells from atopic asthmatic patients exposed to ozone display an enhanced innate immune gene profile", J Allergy Clin Immunol, 129, pp.259~261 (2012)
- Bousquet J, "Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen)", Allergy, 63(Suppl 86), pp.8~160 (2008)
- Pipkorn U, "Inhibition of mediator release in allergic rhinitis by pretreatment with topical glucocorticosteroids", N Engl J Med, 316, pp.1506~1510 (1987)
- Ramey JT, "Rhinitis medicamentosa", J Investig Allergol Clin Immunol, 16, pp.148~155 (2006)
- Papadopoulos NG, "The efficacy of montelukast during the allergy season in pediatric patients with persistent asthma and seasonal aeroallergen sensitivity", J Asthma, 46, pp.413~420 (2009)
- Zhang T, "Mast cell stabilisers", Eur J Pharmacol, 778, pp.158~168 (2016)
- Bosnic-Anticevich S, "ARIA pharmacy 2018 "Allergic rhinitis care pathways for community pharmacy": AIRWAYS ICPs initiative (European Innovation Partnership on Active and Healthy Ageing, DG CONNECT and DG Sante) POLLAR (Impact of Air POLLution on Asthma and Rhinitis)GARD Demonstration project", Allergy, 74, pp.1219~1236 (2019)
- Li CH, "Air pollution and allergic rhinitis : role in symptom exacerbation and strategies for management", J Asthma Allergy, 13, pp.285~292 (2020)
- Cooney DJ, "The generation of diesel exhaust particle aerosols from a bulk source in an aerodynamic size range similar to atmospheric particles", Int J Nanomedicine, 3, pp.435~449 (2008)
- 박경희, "Effects of Air Purifiers on Patients with Allergic Rhinitis: a Multicenter, Randomized, Double-Blind, and Placebo-Controlled Study", Yonsei Medical Journal, 61(8), pp.689~697 (2020), 연세대학교의과대학[DOI]
- Li L, "Efficacy of indoor air purification in the treatment of Artemisia pollen-allergic rhinitis : a randomised, double-blind, clinical controlled trial", Clin Otolaryngol, 45, pp.394~401 (2020)