정신건강의학과에서 경두개 직류자극술의 활용
Application of Transcranial Direct Current Stimulation in Psychiatry
2
조회
0
다운로드
5
인용
0
참고문헌
키워드
초록
Transcranial cranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique that consists of applying a weak current over the scalp to modulate cortical excitability by facilitating or inhibiting ongoing neuronal processes. tDCS is attracting much attention among researchers and clinicians because it has a low risk and low cost, and it is simple to operate, being portable. In this review, the authors provide a summary of developmental history, technical aspects and mechanism of action of tDCS and review the current literature regarding the use of tDCS in psychiatry. Depression was the most extensively researched condition, followed by schizophrenia, substance use disorders, and obsessive-compulsive disorder. Other topics explored were child and adolescent psychiatry. This review suggested that tDCS interventions comprising multiple sessions can alleviate symptoms of several major psychiatric disorders, both acutely and in the long-term and are well tolerated and safe for patients including child and adolescent. Nevertheless, the number of publications regarding tDCS is low and randomized controlled trials are very few. Evidence from large-scale, multi-center randomized controlled trials is required to transition this technique from the laboratory to the clinic. In addition, tDCS parameters such as electrode size, dosage, and location of electrode should be investigated.
Abstract
Transcranial cranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique that consists of applying a weak current over the scalp to modulate cortical excitability by facilitating or inhibiting ongoing neuronal processes. tDCS is attracting much attention among researchers and clinicians because it has a low risk and low cost, and it is simple to operate, being portable. In this review, the authors provide a summary of developmental history, technical aspects and mechanism of action of tDCS and review the current literature regarding the use of tDCS in psychiatry. Depression was the most extensively researched condition, followed by schizophrenia, substance use disorders, and obsessive-compulsive disorder. Other topics explored were child and adolescent psychiatry. This review suggested that tDCS interventions comprising multiple sessions can alleviate symptoms of several major psychiatric disorders, both acutely and in the long-term and are well tolerated and safe for patients including child and adolescent. Nevertheless, the number of publications regarding tDCS is low and randomized controlled trials are very few. Evidence from large-scale, multi-center randomized controlled trials is required to transition this technique from the laboratory to the clinic. In addition, tDCS parameters such as electrode size, dosage, and location of electrode should be investigated.
참고문헌 (83)
- Pascual-Leone A, "A brief summary of the history of noninvasive brain stimulation", Annu Rev Biomed Eng, 9, pp.527~565 (2007)
- Barker AT, "Non-invasive magnetic stimulation of human motor cortex", Lancet, 1, pp.1106~1107 (1985)
- Priori A, "Polarization of the human motor cortex through the scalp", Neuroreport, 9, pp.2257~2260 (1998)
- André Aleman, "Use of Repetitive Transcranial Magnetic Stimulation for Treatment in Psychiatry", Clinical Psychopharmacology and Neuroscience, 11(2), pp.53~59 (2013), 대한정신약물학회
- Kekic M, "A systematic review of the clinical efficacy of transcranial direct current stimulation (tDCS) in psychiatric disorders", J Psychiatr Res, 74, pp.70~86 (2016)
- Jo JM, "Enhancing the working memory of stroke patients using tDCS", Am J Phys Med Rehabil, 88, pp.404~409 (2009)
- Nitsche MA, "Catecholaminergic consolidation of motor cortical neuroplasticity in humans", Cereb Cortex, 14, pp.1240~1245 (2004)
- Paulus W, "Transcranial electrical stimulation (tES - tDCS; tRNS, tACS) methods", Neuropsychol Rehabil, 21, pp.602~617 (2011)
- Bikson M, "Effects of uniform extracellular DC electric fields on excitability in rat hippocampal slices in vitro", J Physiol, 557(Pt 1), pp.175~190 (2004)
- Nitsche MA, "Treatment of depression with transcranial direct current stimulation (tDCS): a review", Exp Neurol, 219, pp.14~19 (2009)
- Kuo HI, "Comparing cortical plasticity induced by conventional and high-definition 4 × 1 ring tDCS: a neurophysiological study", Brain Stimul, 6, pp.644~648 (2013)
- Stagg CJ, "Physiological basis of transcranial direct current stimulation", Neuroscientist, 17, pp.37~53 (2011)
- Shahid S, "Numerical investigation of white matter anisotropic conductivity in defining current distribution under tDCS", Comput Methods Programs Biomed, 109, pp.48~64 (2013)
- Zaghi S, "Noninvasive brain stimulation with low-intensity electrical currents: putative mechanisms of action for direct and alternating current stimulation", Neuroscientist, 16, pp.285~307 (2010)
- Ferrucci R, "Transcranial cerebellar direct current stimulation (tcDCS): motor control, cognition, learning and emotions", Neuroimage, 85(Pt 3), pp.918~923 (2014)
- Antal A, "Transcranial direct current stimulation and visual perception", Perception, 37, pp.367~374 (2008)
- Oliveira JF, "Acute working memory improvement after tDCS in antidepressant-free patients with major depressive disorder", Neurosci Lett, 537, pp.60~64 (2013)
- Tedesco Triccas L, "Multiple sessions of transcranial direct current stimulation and upper extremity rehabilitation in stroke: a review and meta-analysis", Clin Neurophysiol, 127, pp.946~955 (2016)
- Boggio PS, "Repeated sessions of noninvasive brain DC stimulation is associated with motor function improvement in stroke patients", Restor Neurol Neurosci, 25, pp.123~129 (2007)
- Liebetanz D, "Pharmacological approach to the mechanisms of transcranial DC-stimulation-induced after-effects of human motor cortex excitability", Brain, 125(Pt 10), pp.2238~2247 (2002)
- Wagner T, "Noninvasive human brain stimulation", Annu Rev Biomed Eng, 9, pp.527~565 (2007)
- Brunoni AR, "Clinical research with transcranial direct current stimulation (tDCS): challenges and future directions", Brain Stimul, 5, pp.175~195 (2012)
- 김덕용, "만성 뇌졸중 후 편마비 환자에서 2주간 경두개 전기 자극 후 상지 운동기능 향상", Annals of Rehabilitation Medicine, 33(1), pp.5~11 (2009), 대한재활의학회
- Bikson M, "Establishing safety limits for transcranial direct current stimulation", Clin Neurophysiol, 120, pp.1033~1034 (2009)
- Knotkova H, "Safety of the transcranial direct current stimulation (tDCS): evaluation of 815 tDCS sessions in 100 chronic-pain patients", J Pain, 12, pp.54~ (2011)
- Brunoni AR, "A systematic review on reporting and assessment of adverse effects associated with transcranial direct current stimulation", Int J Neuropsychopharmacol, 14, pp.1133~1145 (2011)
- Vicario CM, "Non-invasive brain stimulation for the treatment of brain diseases in childhood and adolescence: state of the art, current limits and future challenges", Front Syst Neurosci, 7, pp.94~ (2013)
- Andrade C, "Transcranial direct current stimulation for refractory auditory hallucinations in schizophrenia", J Clin Psychiatry, 74, pp.e1054~e1058 (2013)
- Kessler SK, "Dosage considerations for transcranial direct current stimulation in children: a computational modeling study", PLoS One, 8, pp.e76112~ (2013)
- Kessler RC, "Age differences in major depression: results from the National Comorbidity Survey Replication (NCS-R)", Psychol Med, 40, pp.225~237 (2010)
- Palm U, "Transcranial direct current stimulation in treatment resistant depression:a randomized double-blind, placebo-controlled study", Brain Stimul, 5, pp.242~251 (2012)
- Bueno VF, "Mood and cognitive effects of transcranial direct current stimulation in poststroke depression", Neurocase, 17, pp.318~322 (2011)
- Grimm S, "Imbalance between left and right dorsolateral prefrontal cortex in major depression is linked to negative emotional judgment: an fMRI study in severe major depressive disorder", Biol Psychiatry, 63, pp.369~376 (2008)
- Northoff G, "The ‘resting-state hypothesis’ of major depressive disorder-a translational subcorticalcortical framework for a system disorder", Neurosci Biobehav Rev, 35, pp.1929~1945 (2011)
- Schutter DJ, "Antidepressant efficacy of high-frequency transcranial magnetic stimulation over the left dorsolateral prefrontal cortex in double-blind sham-controlled designs: a meta-analysis", Psychol Med, 39, pp.65~75 (2009)
- Kalu UG, "Transcranial direct current stimulation in the treatment of major depression: a meta-analysis", Psychol Med, 42, pp.1791~1800 (2012)
- Berlim MT, "Clinical utility of transcranial direct current stimulation (tDCS) for treating major depression:a systematic review and meta-analysis of randomized, doubleblind and sham-controlled trials", J Psychiatr Res, 47, pp.1~7 (2013)
- Brunoni AR, "The sertraline vs. electrical current therapy for treating depression clinical study: results from a factorial, randomized, controlled trial", JAMA Psychiatry, 70, pp.383~391 (2013)
- Valiengo L, "The sertraline versus electrical current therapy for treating depression clinical study (select-TDCS): results of the crossover and follow-up phases", Depress Anxiety, 30, pp.646~653 (2013)
- McGrath J, "Schizophrenia: a concise overview of incidence, prevalence, and mortality", Epidemiol Rev, 30, pp.67~76 (2008)
- Leucht S, "Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis", Lancet, 382, pp.951~962 (2013)
- Shi C, "Revisiting the therapeutic effect of rTMS on negative symptoms in schizophrenia: a metaanalysis", Psychiatry Res, 215, pp.505~513 (2014)
- Slotema CW, "Review of the efficacy of transcranial magnetic stimulation for auditory verbal hallucinations", Biol Psychiatry, 76, pp.101~110 (2014)
- Brunelin J, "Examining transcranial direct-current stimulation (tDCS) as a treatment for hallucinations in schizophrenia", Am J Psychiatry, 169, pp.719~724 (2012)
- Mondino M, "Fronto-temporal transcranial direct current stimulation (tDCS) reduces source-monitoring deficits and auditory hallucinations in patients with schizophrenia", Schizophr Res, 161, pp.515~516 (2015)
- Bose A, "Insight facilitation with add-on tDCS in schizophrenia", Schizophr Res, 156, pp.63~65 (2014)
- Brunelin J, "Nicotine smoking prevents the effects of frontotemporal transcranial direct current stimulation (tDCS) in hallucinating patients with schizophrenia", Brain Stimul, 8, pp.1225~1227 (2015)
- Shivakumar V, "Effect of tDCS on auditory hallucinations in schizophrenia:Influence of catechol-O-methyltransferase (COMT) Val-158Met polymorphism", Asian J Psychiatr, 16, pp.75~77 (2015)
- Palm U, "Prefrontal transcranial direct current stimulation (tDCS)changes negative symptoms and functional connectivity MRI (fcMRI)in a single case of treatment-resistant schizophrenia", Schizophr Res, 150, pp.583~585 (2013)
- Smith RC, "Effects of transcranial direct current stimulation (tDCS) on cognition, symptoms, and smoking in schizophrenia: a randomized controlled study", Schizophr Res, 168, pp.260~266 (2015)
- Shiozawa P, "Transcranial direct current stimulation (tDCS) for catatonic schizophrenia:a case study", Schizophr Res, 146, pp.374~375 (2013)
- Homan P, "Muting the voice: a case of arterial spin labeling-monitored transcranial direct current stimulation treatment of auditory verbal hallucinations", Am J Psychiatry, 168, pp.853~854 (2011)
- Sri Mahavir Agarwal, "Transcranial Direct Current Stimulation in Schizophrenia", Clinical Psychopharmacology and Neuroscience, 11(3), pp.118~125 (2013), 대한정신약물학회
- Poreisz C, "Safety aspects of transcranial direct current stimulation concerning healthy subjects and patients", Brain Res Bull, 72, pp.208~214 (2007)
- Shenoy S, "Transcranial direct current stimulation (tDCS) for auditory verbal hallucinations in schizophrenia during pregnancy: a case report", Brain Stimul, 8, pp.163~164 (2015)
- Kalivas PW, "Drug addiction as a pathology of staged neuroplasticity", Neuropsychopharmacology, 33, pp.166~180 (2008)
- Engelmann JM, "Neural substrates of smoking cue reactivity: a meta-analysis of fMRI studies", Neuroimage, 60, pp.252~262 (2012)
- Boggio PS, "Prefrontal cortex modulation using transcranial DC stimulation reduces alcohol craving: a double-blind, sham-controlled study", Drug Alcohol Depend, 92, pp.55~60 (2008)
- da Silva MC, "Behavioral effects of transcranial direct current stimulation (tDCS) induced dorsolateral prefrontal cortex plasticity in alcohol dependence", J Physiol Paris, 107, pp.493~502 (2013)
- Klauss J, "A randomized controlled trial of targeted prefrontal cortex modulation with tDCS in patients with alcohol dependence", Int J Neuropsychopharmacol, 17, pp.1793~1803 (2014)
- Fregni F, "Cortical stimulation of the prefrontal cortex with transcranial direct current stimulation reduces cue-provoked smoking craving: a randomized, sham-controlled study", J Clin Psychiatry, 69, pp.32~40 (2008)
- Boggio PS, "Cumulative priming effects of cortical stimulation on smoking cue-induced craving", Neurosci Lett, 463, pp.82~86 (2009)
- Fecteau S, "Modulation of smoking and decision-making behaviors with transcranial direct current stimulation in tobacco smokers: a preliminary study", Drug Alcohol Depend, 140, pp.78~84 (2014)
- Conti CL, "Cognitive related electrophysiological changes induced by noninvasive cortical electrical stimulation in crack-cocaine addiction", Int J Neuropsychopharmacol, 17, pp.1465~1475 (2014)
- Batista EK, "A randomized placebo-controlled trial of targeted prefrontal cortex modulation with bilateral tDCS in patients with crack-cocaine dependence", Int J Neuropsychopharmacol (2015)
- Boggio PS, "Modulation of risk-taking in marijuana users by transcranial direct current stimulation (tDCS) of the dorsolateral prefrontal cortex (DLPFC)", Drug Alcohol Depend, 112, pp.220~225 (2010)
- Shahbabaie A, "State dependent effect of transcranial direct current stimulation (tDCS) on methamphetamine craving", Int J Neuropsychopharmacol, 17, pp.1591~1598 (2014)
- Milad MR, "Obsessive-compulsive disorder: beyond segregated cortico-striatal pathways", Trends Cogn Sci, 16, pp.43~51 (2012)
- Mondino M, "Efficacy of cathodal transcranial direct current stimulation over the left orbitofrontal cortex in a patient with treatment-resistant obsessive-compulsive disorder", J ECT, 31, pp.271~272 (2015)
- Narayanaswamy JC, "Successful application of add-on transcranial direct current stimulation (tDCS) for teatment of SSRI resistant OCD", Brain Stimul, 8, pp.655~657 (2015)
- D’Urso G, "Polarity-dependent effects of transcranial direct current stimulation in obsessive-compulsive disorder", Neurocase, 22, pp.60~64 (2016)
- Das S, "Polarity-dependent effects of trans-cranial direct current stimulation (tDCS) in cerebellar learning depends on the state of neuronal network", Brain Stimul, 7, pp.e3~ (2014)
- de Wit SJ, "Presupplementary motor area hyperactivity during response inhibition: a candidate endophenotype of obsessivecompulsive disorder", Am J Psychiatry, 169, pp.1100~1108 (2012)
- Senço NM, "Transcranial direct current stimulation in obsessive-compulsive disorder: emerging clinical evidence and considerations for optimal montage of electrodes", Expert Rev Med Devices, 12, pp.381~391 (2015)
- Patel V, "Mental health of young people: a global public-health challenge", Lancet, 369, pp.1302~1313 (2007)
- Rubio-Morell B, "The use of noninvasive brain stimulation in childhood psychiatric disorders: new diagnostic and therapeutic opportunities and challenges", Rev Neurol, 53, pp.209~225 (2011)
- Schneider HD, "The use of the Bilingual Aphasia Test for assessment and transcranial direct current stimulation to modulate language acquisition in minimally verbal children with autism", Clin Linguist Phon, 25, pp.640~654 (2011)
- Amatachaya A, "Effect of anodal transcranial direct current stimulation on autism: a randomized double-blind crossover trial", Behav Neurol, 2014, pp.173073~ (2014)
- Mattai A, "Tolerability of transcranial direct current stimulation in childhoodonset schizophrenia", Brain Stimul, 4, pp.275~280 (2011)
- Cosmo C, "A randomized, double-blind, sham-controlled trial of transcranial direct current stimulation in attention-deficit", hyperactivity disorder, 2015, pp.10, e0135371~
- Moliadze V, "Stimulation intensities of transcranial direct current stimulation have to be adjusted in children and adolescents", Clin Neurophysiol, 126, pp.1392~1399 (2015)
- George MS, "Noninvasive techniques for probing neurocircuitry and treating illness: vagus nerve stimulation (VNS), transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS)", Neuropsychopharmacology, 35, pp.301~316 (2010)
- Tortella G, "Transcranial direct current stimulation in psychiatric disorders", World J Psychiatry, 5, pp.88~102 (2015)
