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초기 정신증 환자에서 병전 외상력에 따른 증상, 기능과 예후의 차이

Differences in Symptoms, Functions, and Their Outcomes According to the Degree of Trauma in Patients with Early Psychosis

김정진|정영철|이승환|이규영|김승현|이봉주|김성완|김의태|원승희|윤지애|유제춘|문서영|박염홍|강시현
대한신경정신의학회 (Korean Neuropsychiatric Association)|2020.08|신경정신의학 (JOURNAL OF THE KOREAN NEUROPSYCHIATRIC ASSOCIATION)|제59권 제3호|pp. 228-235|DOI https://doi.org/10.4306/jknpa.2020.59.3.228

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참고문헌

주제분류정신과학

초록

Objectives There has been growing interest in the relationship between mental illness and premorbid trauma recently. The purpose of this study was to examine the difference in symptoms, functions, and their outcomes according to the degree of trauma in patients with early psychosis. Methods The study involved 226 people who participated in the Korean Early Psychosis Cohort Study, and we divided the participants into two groups according to the degree of trauma. Positive and Negative Syndrome Scale (PANSS) and Social and Occupational Functioning Assessment Scale (SOFAS) were compared at the start of the study and at 12 months after the treatment using paired t-test and repeated measures analysis of variance. Results At the beginning of the study, there was no significant difference between the two groups. But after 12 months of treatment, the high trauma group showed less improvement in PANSS negative score, general psychopathological score, total score, and SOFAS than the low trauma group. Conclusion In patients with early psychosis and at least moderate severity of premorbid trauma, negative symptoms, general psychopathological, and social and occupational functional improvements after treatment are less.

Abstract

Objectives There has been growing interest in the relationship between mental illness and premorbid trauma recently. The purpose of this study was to examine the difference in symptoms, functions, and their outcomes according to the degree of trauma in patients with early psychosis. Methods The study involved 226 people who participated in the Korean Early Psychosis Cohort Study, and we divided the participants into two groups according to the degree of trauma. Positive and Negative Syndrome Scale (PANSS) and Social and Occupational Functioning Assessment Scale (SOFAS) were compared at the start of the study and at 12 months after the treatment using paired t-test and repeated measures analysis of variance. Results At the beginning of the study, there was no significant difference between the two groups. But after 12 months of treatment, the high trauma group showed less improvement in PANSS negative score, general psychopathological score, total score, and SOFAS than the low trauma group. Conclusion In patients with early psychosis and at least moderate severity of premorbid trauma, negative symptoms, general psychopathological, and social and occupational functional improvements after treatment are less.

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