본문 바로가기
KERD
논문KCI 등재

성인 주의력결핍 과잉행동장애 환자에서 임상양상과 우울 증상 간의 연관성에 대한 연구: 한국형 성인 주의력결핍 과잉행동장애 평가척도를 중심으로

A Study on the Association Between the Clinical Features of Adult Attention-Deficit/Hyperactivity Disorder and Depressive Symptoms: Focus on Korean Adult Attention-Deficit/Hyperactivity Disorder Rating Scale

2

조회

0

다운로드

1

인용

0

참고문헌

키워드

주제분류정신과학

초록

Objectives This study aimed to investigate the association between depressive symptoms and the clinical features of adult attention-deficit/hyperactivity disorder (ADHD). Methods This study included 40 adult ADHD patients, aged ≥18, who visited the outpatient clinic of the Department of Psychiatry at Ewha Womans University’s Mokdong Hospital. Patients undergoing pharmacological treatment were excluded from the sample of 243 patients. To assess the clinical features of ADHD, the Adult ADHD Self-Report Scale and the Korean Adult Attention- Deficit/Hyperactivity Disorder Rating Scale (K-AARS) were administered to the patients. Depressive symptoms were evaluated using Beck’s Depression Inventory (BDI) questionnaire. Pearson and Spearman correlation analyses were employed to explore the relationship between ADHD and depressive symptoms, and linear regression analyses were used to further investigate their associations. Results Participants were aged 19–54 years (27.47±7.05) and included a higher proportion of males (77.5%). Higher BDI scores were related to unmarried status, coexisting disorders, and lower education of the subjects. Inattention, emotional dysregulation, disorganization, impulsivity, and functional impairment measured by the K-AARS were correlated with higher BDI scores. Multiple linear regression analysis revealed significant associations between disorganization (β=0.858, p=0.008), impulsivity (β=0.759, p=0.001), emotional dysregulation (β=0.464, p<0.001), inattention (β=0.266, p=0.019), and subtotal score (β=0.069, p=0.031) in the K-AARS, and BDI. Conclusion The current study showed that elevated levels of inattention, impulsivity, disorganization, emotional dysregulation, and severity of ADHD symptoms were associated with higher levels of depressive symptoms in patients with adult ADHD. We suggest that it is important to understand the relationship between ADHD and depressive symptoms when managing adult ADHD patients with depressive symptoms.

Abstract

Objectives This study aimed to investigate the association between depressive symptoms and the clinical features of adult attention-deficit/hyperactivity disorder (ADHD). Methods This study included 40 adult ADHD patients, aged ≥18, who visited the outpatient clinic of the Department of Psychiatry at Ewha Womans University’s Mokdong Hospital. Patients undergoing pharmacological treatment were excluded from the sample of 243 patients. To assess the clinical features of ADHD, the Adult ADHD Self-Report Scale and the Korean Adult Attention- Deficit/Hyperactivity Disorder Rating Scale (K-AARS) were administered to the patients. Depressive symptoms were evaluated using Beck’s Depression Inventory (BDI) questionnaire. Pearson and Spearman correlation analyses were employed to explore the relationship between ADHD and depressive symptoms, and linear regression analyses were used to further investigate their associations. Results Participants were aged 19–54 years (27.47±7.05) and included a higher proportion of males (77.5%). Higher BDI scores were related to unmarried status, coexisting disorders, and lower education of the subjects. Inattention, emotional dysregulation, disorganization, impulsivity, and functional impairment measured by the K-AARS were correlated with higher BDI scores. Multiple linear regression analysis revealed significant associations between disorganization (β=0.858, p=0.008), impulsivity (β=0.759, p=0.001), emotional dysregulation (β=0.464, p<0.001), inattention (β=0.266, p=0.019), and subtotal score (β=0.069, p=0.031) in the K-AARS, and BDI. Conclusion The current study showed that elevated levels of inattention, impulsivity, disorganization, emotional dysregulation, and severity of ADHD symptoms were associated with higher levels of depressive symptoms in patients with adult ADHD. We suggest that it is important to understand the relationship between ADHD and depressive symptoms when managing adult ADHD patients with depressive symptoms.

참고문헌 (56)

  1. Simon V, "Prevalence and correlates of adult attention-deficit hyperactivity disorder : meta-analysis", Br J Psychiatry, 194, pp.204~211 (2009)
  2. Song P, "The prevalence of adult attention-deficit hyperactivity disorder : a global systematic review and meta-analysis", J Glob Health, 11, pp.04009~ (2021)
  3. American Psychiatric Association, "Diagnostic and statistical manual of mental disorders (DSM-5). 5th ed", American Psychiatric Association, ~ (2013)
  4. World Health Organization, "International statistical classification of diseases and related health problems (ICD-11). 11th ed", World Health Organization, ~ (2019)
  5. Adler LA, "The structure of adult ADHD", Int J Methods Psychiatr Res, 26, pp.e1555~ (2017)
  6. Faraone SV, "The age-dependent decline of attention deficit hyperactivity disorder : a meta-analysis of follow-up studies", Psychol Med, 36, pp.159~165 (2006)
  7. Kessler RC, "The prevalence and correlates of adult ADHD in the United States : results from the national comorbidity survey replication", Am J Psychiatry, 163, pp.716~723 (2006)
  8. Asherson P, "Under diagnosis of adult ADHD : cultural influences and societal burden", J Atten Disord, 16(5 Suppl), pp.20S~38S (2012)[DOI]
  9. Jang MJ, "Characteristic and educational intervention strategy of adult with attention-deficit", hyperactivity, 2004, pp.20, 43~57
  10. Mörstedt B, "Emotional symptoms and their contribution to functional impairment in adults with attention-deficit", hyperactivity disorder, 2016, pp.8, 21~33
  11. Skirrow C, "Emotional lability, comorbidity and impairment in adults with attention-deficit hyperactivity disorder", J Affect Disord, 147, pp.80~86 (2013)
  12. Barkley RA, "The unique contribution of emotional impulsiveness to impairment in major life activities in hyperactive children as adults", J Am Acad Child Adolesc Psychiatry, 49, pp.503~513 (2010)
  13. 김미란, "성인 ADHD 성향이 우울에 미치는 영향: 정서조절곤란과 자기격려의 매개효과", 한국심리학회지: 건강, 23(2), pp.475~488 (2018), 한국건강심리학회[DOI]
  14. Bodalski EA, "Adult ADHD, emotion dysregulation, and functional outcomes: examining the role of emotion regulation strategies", J Psychopathol Behav Assess, 41, pp.81~92 (2019)
  15. Seymour KE, "Emotion regulation mediates the association between ADHD and depressive symptoms in a community sample of youth", J Abnorm Child Psychol, 42, pp.611~621 (2014)
  16. Katzman MA, "Adult ADHD and comorbid disorders : clinical implications of a dimensional approach", BMC Psychiatry, 17, pp.302~ (2017)
  17. Anbarasan D, "Screening for adult ADHD", Curr Psychiatry Rep, 22, pp.72~ (2020)
  18. Torgersen T, "ADHD in adults: a study of clinical characteristics, impairment and comorbidity", Nord J Psychiatry, 60, pp.38~43 (2006)
  19. Simon V, "Is ADHD severity in adults associated with the lifetime prevalence of comorbid depressive episodes and anxiety disorders?", Eur Psychiatry, 28, pp.308~314 (2013)
  20. Michielsen M, "The comorbidity of anxiety and depressive symptoms in older adults with attention-deficit", hyperactivity disorder : a longitudinal study, 2013, pp.148, 220~227
  21. Matthies S, "The impact of depressive symptoms and traumatic experiences on quality of life in adults with ADHD", J Atten Disord, 22, pp.486~496 (2018)
  22. 강태웅, "한국형 성인 ADHD 평가척도 개발 연구", Journal of the Korean Academy of Child and Adolescent Psychiatry, 26(4), pp.295~310 (2015), 대한소아청소년 정신의학회
  23. 김지혜, "The WHO Adult ADHD Self-Report Scale: Reliability and Validity of the Korean Version", PSYCHIATRY INVESTIGATION, 10(1), pp.41~46 (2013), 대한신경정신의학회[DOI]
  24. Han HM, "A standardization study of beck depression inventory in Korea", J Korean Neuropsychiatr Assoc, 25, pp.487~500 (1986)
  25. Kessler RC, "The World Health Organization adult ADHD self-report scale(ASRS) : a short screening scale for use in the general population", Psychol Med, 35, pp.245~256 (2005)
  26. 홍민하, "Clinical Utility and Cut-Off Scores of the Korean Adult Attention-Deficit", Hyperactivity Disorder Rating Scale, 2019, pp.30(3), 116~120[DOI]
  27. Asherson P, "Adult attention-deficit hyperactivity disorder : key conceptual issues", Lancet Psychiatry, 3, pp.568~578 (2016)
  28. Biederman J, "Age-dependent decline of symptoms of attention deficit hyperactivity disorder : impact of remission definition and symptom type", Am J Psychiatry, 157, pp.816~818 (2000)
  29. Kessler RC, "Structure and diagnosis of adult attention-deficit", hyperactivity disorder : analysis of expanded symptom criteria from the adult ADHD clinical diagnostic scale, 2010, pp.67, 1168~1178
  30. Wehmeier PM, "Social and emotional impairment in children and adolescents with ADHD and the impact on quality of life", J Adolesc Health, 46, pp.209~217 (2010)
  31. Bunford N, "ADHD and emotion dysregulation among children and adolescents", Clin Child Fam Psychol Rev, 18, pp.185~217 (2015)
  32. Young S, "Coping strategies used by adults with ADHD", Pers Individ Differ, 38, pp.809~816 (2005)
  33. Hsu CF, "Differences in perceived mental effort required and discomfort during a working memory task between individuals at-risk and not at-risk for ADHD", Front Psychol, 8, pp.407~ (2017)
  34. Knouse LE, "Depression in adults with attention-deficit", hyperactivity disorder(ADHD) : the mediating role of cognitive-behavioral factors, 2013, pp.37, 1220~1232
  35. Malloy-Diniz L, "Impulsive behavior in adults with attention deficit", hyperactivity disorder:characterization of attentional, motor and cognitive impulsiveness, 2007, pp.13, 693~698
  36. Winstanley CA, "Behavioral models of impulsivity in relation to ADHD : translation between clinical and preclinical studies", Clin Psychol Rev, 26, pp.379~395 (2006)
  37. Harty SC, "Adolescents with childhood ADHD and comorbid disruptive behavior disorders: aggression, anger, and hostility", Child Psychiatry Hum Dev, 40, pp.85~97 (2009)
  38. Berghoff CR, "The relationship between experiential avoidance and impulsiveness in a nonclinical sample", Behav Change, 29, pp.25~35 (2012)
  39. Barbaresi WJ, "Mortality, ADHD, and psychosocial adversity in adults with childhood ADHD: a prospective study", Pediatrics, 131, pp.637~644 (2013)
  40. Park S, "Prevalence, correlates, and comorbidities of adult ADHD symptoms in Korea: results of the Korean epidemiologic catchment area study", Psychiatry Res, 186, pp.378~383 (2011)
  41. Patros CH, "Symptoms of attention-deficit", hyperactivity disorder(ADHD)moderate suicidal behaviors in college students with depressed mood, 2013, pp.69, 980~993
  42. Lin YJ, "Validation of DSM-5 age-of-onset criterion of attention deficit", hyperactivity disorder (ADHD) in adults:comparison of life quality, functional impairment, and family function, 2015, pp.47, 48~60
  43. 서지영, "Mediating Effect of Depressive Symptoms on the Relationship between Adult Attention Deficit Hyperactivity Disorder and Quality of Life", PSYCHIATRY INVESTIGATION, 11(2), pp.131~136 (2014), 대한신경정신의학회[DOI]
  44. Tai YM, "Depression and quality of life mediating the association between attention deficit", hyperactivity disorder and suicidality in military recruits, 2017, pp.182, e1912~e1919
  45. Reimherr FW, "Types of adult attention-deficit hyperactivity disorder (ADHD): baseline characteristics, initial response, and long-term response to treatment with methylphenidate", Atten Defic Hyperact Disord, 7, pp.115~128 (2015)
  46. Adler LA, "Atomoxetine effects on executive function as measured by the BRIEF--a in young adults with ADHD: a randomized, double-blind, placebo-controlled study", PLoS One, 9, pp.e104175~ (2014)
  47. Lenzi F, "Pharmacotherapy of emotional dysregulation in adults with ADHD : a systematic review and metaanalysis", Neurosci Biobehav Rev, 84, pp.359~367 (2018)
  48. Moukhtarian TR, "Effects of stimulants and atomoxetine on emotional lability in adults : a systematic review and meta-analysis", Eur Psychiatry, 44, pp.198~207 (2017)
  49. Safren SA, "Cognitive-behavioral therapy for ADHD in medication-treated adults with continued symptoms", Behav Res Ther, 43, pp.831~842 (2005)
  50. Ramsay JR, "The relevance of cognitive distortions in the psychosocial treatment of adult ADHD", Prof Psychol Res Pract, 48, pp.62~69 (2017)
  51. Stevenson CS, "A cognitive remediation programme for adults with attention deficit hyperactivity disorder", Aust N Z J Psychiatry, 36, pp.610~616 (2002)
  52. Emilsson B, "Cognitive behaviour therapy in medicationtreated adults with ADHD and persistent symptoms : a randomized controlled trial", BMC Psychiatry, 11, pp.116~ (2011)
  53. Pettersson R, "Internet-based cognitive behavioral therapy for adults with ADHD in outpatient psychiatric care : a randomized trial", J Atten Disord, 21, pp.508~521 (2017)
  54. Hesslinger B, "Psychotherapy of attention deficit hyperactivity disorder in adults--a pilot study using a structured skills training program", Eur Arch Psychiatry Clin Neurosci, 252, pp.177~184 (2002)
  55. Philipsen A, "Structured group psychotherapy in adults with attention deficit hyperactivity disorder : results of an open multicentre study", J Nerv Ment Dis, 195, pp.1013~1019 (2007)
  56. Cole P, "CBT", DBT skills training for adults with attention deficit hyperactivity disorder(ADHD), 2016, pp.28(Suppl 1), 103~107

관련 논문AI추천

젊은 성인 남성 우울증 환자에서 성인 ADHD 경향성이 심리학적 특징에 미치는 영향김양태, 정현경대한생물치료정신의학회 · 생물치료정신의학2019 · 제25권 제1호Prevalence and Comorbidities of Adult Attention-deficit/ hyperactivity Disorder in a Community Sample from Korea박원명, Bo-Hyun Yoon, Hyung Mo Sung, Jeong Seok Seo, Jung Goo Lee, Jung Wan Hong, Se-Hoon Shim, Sung-Yong Park, Young Sup Woo대한정신약물학회 · Clinical Psychopharmacology and Neuroscience2023 · 제21권 제4호젊은 성인 남성 우울증 환자에서 ADHD 경향성에 따른 인지기능의 특징김양태, 신소정, 이호준, 정성원대한생물치료정신의학회 · 생물치료정신의학2021 · 제27권 제1호군인들에서 성인 주의력결핍 과잉행동장애, 우울 그리고 자살 사고의 관계김봉조, 박철수, 서지영, 이동윤, 이소진, 이철순, 차보석대한생물치료정신의학회 · 생물치료정신의학2012 · 제18권 제2호군인들에서 성인 주의력 결핍 과잉 행동 장애 증상이 스트레스와 우울증에 미치는 영향김봉조, 박철수, 방수영, 서지영, 이소진, 이철순, 차보석대한불안의학회 · 대한불안의학회지2011 · 제7권 제2호성인 남자 주의력결핍 과잉행동장애 환자에서 인터넷 중독 성향에 관여하는 특성김붕년, 김준원, 노동현, 민경준, 안지영, 이영식, 정재훈, 한덕현대한신경정신의학회 · 신경정신의학2014 · 제53권 제3호

이 간행물의 다른 논문 (7건)