본문 바로가기
KERD
논문KCI 등재

소아 알레르기비염의 임상 특징

Clinical features of allergic rhinitis in Korean children

2

조회

0

다운로드

11

인용

0

참고문헌

키워드

주제분류소아과학

초록

Purpose: The characteristics of allergic rhinitis can be different among countries and areas because causative allergens and aggravating factors depend on the living environment. However, there have been few studies on the clinical feature of Korean children with allergic rhinitis, as well as on clinical characteristics in different age groups. The aim of this study was to investigate the clinical characteristics of Korean children with allergic rhinitis. Methods: The medical records of children under 12 years of age who had rhinitis symptoms were analyzed in terms of clinical symptoms and positive allergens. Subjects were classified into 2 groups: those with allergic rhinitis (AR group) and nonallergic rhinitis (NAR group). Both groups were subdivided into 3 categories: the 1–4 years, 5–8 years, and 9–12 age groups. Results: Among 516 children, 397 (76.94%) belonged to the AR group and 119 (23.06%) belonged to the NAR group. The male to female ratios were 2:1 in both groups. There were significant differences in sneezing and itching between the AR and NAR groups across different age subgroups. There were significant differences in nasal obstruction between the AR and NAR groups in the 9–12 age group. The incidence of AR was 77.8 % in chronic sinusitis patients. Sensitized allergens were house dust mites, animal hair, pollen, and mold in decreasing order in the AR group. Children who were sensitized to animal hair more frequently had sneezing than those who were not. Conclusion: Sneezing and itching strongly suggest allergic rhinitis in Korean children. Clinical characteristics of allergic rhinitis in Korean children would helpful in early diagnosis and adequate treatment of disease.

Abstract

Purpose: The characteristics of allergic rhinitis can be different among countries and areas because causative allergens and aggravating factors depend on the living environment. However, there have been few studies on the clinical feature of Korean children with allergic rhinitis, as well as on clinical characteristics in different age groups. The aim of this study was to investigate the clinical characteristics of Korean children with allergic rhinitis. Methods: The medical records of children under 12 years of age who had rhinitis symptoms were analyzed in terms of clinical symptoms and positive allergens. Subjects were classified into 2 groups: those with allergic rhinitis (AR group) and nonallergic rhinitis (NAR group). Both groups were subdivided into 3 categories: the 1–4 years, 5–8 years, and 9–12 age groups. Results: Among 516 children, 397 (76.94%) belonged to the AR group and 119 (23.06%) belonged to the NAR group. The male to female ratios were 2:1 in both groups. There were significant differences in sneezing and itching between the AR and NAR groups across different age subgroups. There were significant differences in nasal obstruction between the AR and NAR groups in the 9–12 age group. The incidence of AR was 77.8 % in chronic sinusitis patients. Sensitized allergens were house dust mites, animal hair, pollen, and mold in decreasing order in the AR group. Children who were sensitized to animal hair more frequently had sneezing than those who were not. Conclusion: Sneezing and itching strongly suggest allergic rhinitis in Korean children. Clinical characteristics of allergic rhinitis in Korean children would helpful in early diagnosis and adequate treatment of disease.

참고문헌 (32)

  1. Bousquet J, "Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen)", Allergy, 63(Suppl 86), pp.8~160 (2008)
  2. Long A, "Management of allergic and nonallergic rhinitis", Evid Rep Technol Assess (Summ), 4(54), pp.1~6 (2002)
  3. Bauchau V, "Prevalence and rate of diagnosis of allergic rhinitis in Europe", Eur Respir J, 24, pp.758~764 (2004)
  4. Bachert C, "Prevalence, classification and perception of allergic and nonallergic rhinitis in Belgium", Allergy, 61, pp.693~698 (2006)
  5. Nathan RA, "The prevalence of nasal symptoms attributed to allergies in the United States : findings from the burden of rhinitis in an America survey", Allergy Asthma Proc, 29, pp.600~608 (2008)
  6. Bjorksten B, "Worldwide time trends for symptoms of rhinitis and conjunctivitis: phase III of the International Study of Asthma and Aller gies in Childhood", Pediatr Allergy Immunol, 19, pp.110~124 (2008)
  7. 홍수종, "한국 소아알레르기 질환의 유병률", Korean Journal of Pediatrics, 51(4), pp.343~350 (2008), 대한소아과학회
  8. 지혜미, "2006년 초등학생의 알레르기 질환 유병률의 전국적 역학조사", Allergy Asthma & Respiratory Diseases, 19(2), pp.165~172 (2009), 대한 소아알레르기 호흡기학회
  9. 안강모, "2010년 한국 어린이·청소년의 천식, 알레르기 비결막염, 아토피피부염 증상 유병률 조사: 복합표본설계를 이용한 전국 서베이", 대한의사협회지, 54(7), pp.769~778 (2011), 대한의사협회
  10. Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema: ISAAC, "The International Study of Asthma and Allergies in Childhood (ISAAC) Steering Committee", Lancet, 351, pp.1225~1232 (1998)
  11. Ellwood P, "The international study of asthma and allergies in childhood(ISAAC) : phase three rationale and methods", Int J Tuberc Lung Dis, 9, pp.10~16 (2005)
  12. Miller RL, "Environmental epigenetics and asthma : current concepts and call for studies", Am J Respir Crit Care Med, 177, pp.567~573 (2008)
  13. Hwang CY, "Prevalence of atopic dermatitis, allergic rhinitis and asthma in Taiwan: a national study 2000 to 2007", Acta Derm Venereol, 90, pp.589~594 (2010)
  14. van Rijswijk JB, "Idiopathic rhinitis, the ongoing quest", Allergy, 60, pp.1471~1481 (2005)
  15. 고영일, "알레르기 비염의 진단", 대한내과학회지, 85(5), pp.452~456 (2013), 대한내과학회[DOI]
  16. Jang TY, "Detection of specific lgE antibody from nasal secretion in allergic rhinitis with negative results of skin test and RAST on D.P", Korean J Otolaryngol-Head Neck Surg, 43, pp.1318~1322 (2000)
  17. Wong V, "Early pollen sensitization in children is dependent upon regional aeroallergen exposure", J Allergy(Cairo), 2012, pp.583765~ (2012)
  18. Talay F, "Prevalence and risk factors of asthma and allergic diseases among schoolchildren in Bolu, Turkey", Acta Paediatr, 97, pp.459~462 (2008)
  19. Demir AU, "Asthma and allergic diseases in schoolchildren: third cross-sectional survey in the same primary school in Ankara, Turkey", Pediatr Allergy Immunol, 15, pp.531~538 (2004)
  20. Bousquet J, "World Health Organization. Allergic rhinitis and its impact on asthma", J Allergy Clin Immunol, 108(5 Suppl), pp.S147~S334 (2001)
  21. Criddle MW, "Pediatric chronic rhinosinusitis : a retrospective review", Am J Otolaryngol, 29, pp.372~378 (2008)
  22. Michael G, "Scott-Brown's otolaryngology, head and neck surgery", pp.1097~1101 (2008), Hodder Arnold
  23. Raman R, "Vasomotor rhinitis-atrophic rhinitis : two ends of an autonomic spectrum", Singapore Med J, 30, pp.94~96 (1989)
  24. Smith L, "Special considerations for the child with airway disease", J Allergy Clin Immunol, 101(2 Pt 2), pp.S370~S372 (1998)
  25. 이상민, "알레르기 비염의 분류 및 역학", 대한내과학회지, 85(5), pp.445~451 (2013), 대한내과학회[DOI]
  26. Korea Health Statistics 2011: Korea National Health and Nutrition Examination Survey (KNHANES V-2), "Ministry of Health & Welfare", Ministry of Health & Welfare, Korea Centers for Disease Control and Prevention, ~ (2012)
  27. Weiland SK, "Prevalence of respiratory and atopic disorders among children in the East and West of Germany five years after unification", Eur Respir J, 14, pp.862~870 (1999)
  28. 이지은, "Variability of Offending Allergens of Allergic Rhinitis According to Age: Optimization of Skin Prick Test Allergens", Allergy, Asthma & Immunology Research, 6(1), pp.47~54 (2014), 대한천식알레르기학회
  29. So Hyun Park, "Sensitization rates of airborne pollen and mold in children", Korean Journal of Pediatrics, 55(9), pp.372~379 (2012), 대한소아과학회
  30. 황선혜, "한국 소아의 알레르기비염 역학", Allergy Asthma & Respiratory Diseases, 1(4), pp.321~332 (2013), 대한 소아알레르기 호흡기학회
  31. Salo PM, "Prevalence of allergic sensitization in the United States : results from the National Health and Nutrition Examination Survey(NHANES)2005-2006", J Allergy Clin Immunol, 134, pp.350~359 (2014)
  32. Galant S, "Prevalence of sensitization to aeroallergens in California patients with respiratory allergy. Allergy Skin Test Project Team", Ann Allergy Asthma Immunol, 81, pp.203~210 (1998)

관련 논문AI추천

소아에서 알레르기 및 비알레르기비염의 임상 증상 비교김정은, 안지영, 최봉석대한 소아알레르기 호흡기학회 · Allergy Asthma & Respiratory Disease2015 · 제3권 제5호소아청소년 알레르기비염과 비알레르기비염 환자의 임상적 특징유영, 권정현, 김채봉, 박상현, 서원희, 송대진, 안소현, 원나혜대한 소아알레르기 호흡기학회 · Allergy Asthma & Respiratory Disease2020 · 제8권 제1호한국 소아의 알레르기비염 역학김수영, 김양호, 김정희, 손병관, 양준모, 오인보, 이근화, 이지호, 이혜숙, 임대현, 정숙영, 홍성철, 황선혜대한 소아알레르기 호흡기학회 · Allergy Asthma & Respiratory Disease2013 · 제1권 제4호Natural Course of Allergic and Nonallergic Rhinitis After 2 Years in Korean Children김진국, 이승훈, 정소정, 조재훈, 최지호, 홍석찬, Jeffrey D. Suh대한이비인후과학회 · Clinical and Experimental Otorhinolaryngology2016 · 제9권 제3호소아청소년 알레르기비염의 주요 역학적 특성과 자연경과박양, 대한 소아알레르기 호흡기학회 비염연구회, 김민지, 김현희, 김효빈, 나영호, 박용민, 성명순, 신윤호, 염혜영, 이경석, 이용주, 전윤홍, 지혜미, 최봉석, 최선희대한 소아알레르기 호흡기학회 · Allergy Asthma & Respiratory Disease2021 · 제9권 제4호한국 초·중·고등학생 알레르기비염의 전국 유병률과 위험 인자에 대한 분석이은, 강희태, 권지원, 김수영, 김수진, 김영호, 김유미, 김환철, 백영욱, 범은애, 사공준, 서주희, 손미아, 양송이, 오경재, 이기재, 이철갑, 임신예, 정해관, 조현주, 하미나, 홍수종대한 소아알레르기 호흡기학회 · Allergy Asthma & Respiratory Disease2015 · 제3권 제4호

이 간행물의 다른 논문 (13건)