Low Cost and Portable Parahydrogen Generator for the PHIP
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초록
In the developed NMR hyperpolarization techniques, Parahydrogen-Induced Polarization (PHIP) technique is widely utilized to overcome the low sensitivity of the NMR/MRI. Parahydrogen generator is essential to produce high spin order of parahydrogen molecule. Commercial parahydrogen generator is well developed with user-friendly systems. However, it has drawbacks of long preparation time (~ 2h including cooling down time of 1h) and high cost (~ 200 million won) for the commercial setup. We designed a simple and portable parahydrogen generating system with low cost (~ 2 million won), which produce polarization in less than 1 min. With the designed parahydrogen generator, we successfully performed the PHIP with Wilkinson’s catalyst on styrene. This study will broaden the parahydrogen based polarization transfer study on many researchers by providing the simple portable and low cost parahydrogen generator.
Abstract
In the developed NMR hyperpolarization techniques, Parahydrogen-Induced Polarization (PHIP) technique is widely utilized to overcome the low sensitivity of the NMR/MRI. Parahydrogen generator is essential to produce high spin order of parahydrogen molecule. Commercial parahydrogen generator is well developed with user-friendly systems. However, it has drawbacks of long preparation time (~ 2h including cooling down time of 1h) and high cost (~ 200 million won) for the commercial setup. We designed a simple and portable parahydrogen generating system with low cost (~ 2 million won), which produce polarization in less than 1 min. With the designed parahydrogen generator, we successfully performed the PHIP with Wilkinson’s catalyst on styrene. This study will broaden the parahydrogen based polarization transfer study on many researchers by providing the simple portable and low cost parahydrogen generator.
참고문헌 (18)
- 고혜지, "Hyperpolarization: Sensitivity Boost in Magnetic Resonance Spectroscopy and Imaging", Journal of the Korean Magnetic Resonance Society, 19(3), pp.124~131 (2015), 한국자기공명학회[DOI]
- 임종혁, "Sensitivity Enhancement in Solution NMR via Photochemically Induced Dynamic Nuclear Polarization", Journal of the Korean Magnetic Resonance Society, 21(1), pp.1~6 (2017), 한국자기공명학회
- T. Walker, , Rev. Mod. Phys, 69, pp.629~ (1997)
- C. Witte, , NMR Biomed, 26, pp.788~ (2013)
- C. Bowers, , Phys. Rev. Lett, 57, pp.2645~ (1986)
- J. Natterer, , Prog. Nucl. Magn. Reson. Spectrosc, 31, pp.293~ (1997)
- 정근홍, "Minireview on Nuclear Spin Polarization in Optically-Pumped Diamond Nitrogen Vacancy Centers", Journal of the Korean Magnetic Resonance Society, 20(4), pp.114~120 (2016), 한국자기공명학회
- K. V. Kovtunov, , Top Catal, 59, pp.1686~ (2016)
- U. Obenaus, , J. Phys. Chem. C, 121, pp.9953~ (2017)
- O. G. Salnikov, , Sci. Rep, 5, pp.13930~ (2015)
- F. Reineri, , Nature Comm, 6, pp.5858~ (2015)
- T. C. Eisenschmid, , J. Am. Chem. Soc, 109, pp.8089~ (1987)
- T. Theis, , J. Am. Chem. Soc, 137, pp.1404~ (2015)
- W. Jiang, , Sci. Rep. B, 5, pp.9104~ (2015)
- T. Theis, , J. Magn. Reson, 248, pp.23~ (2014)
- F. Shi, , Angew. Chem. Int. Ed, 53, pp.7495~ (2014)
- J. A. Osborn, , Inorg. Synth, 10, pp.67~ (1967)
- S. Bouguet-Bonnet, , J. Chem. Phys, 130, pp.234507~ (2009)
