Four New Furanosesquiterpenes Isolated from the Marine Sponge Dysidea species
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
From a marine sponge Dysidea species, four new furanosesquiterterpenoids were isolated and characterized. Their structural elucidation was achieved through an extensive analysis employing NMR, MS data, and DFT method. Notably, all compounds shared as identical molecular formula. Compound 2 was identified as a derivative of compound 1, while compounds 3 and 4 exhibited an identical planar structure. Determination of the configurations of chiral centers in compounds 1 and 2 involved a comparative analysis between measured and calculated ECD spectra, along with the application of DP4+ probability analysis. Distinctly, the configurations of isomers 3 and 4 were established by scrutinizing proton chemical shifts based on the NOE correlation.
Abstract
From a marine sponge Dysidea species, four new furanosesquiterterpenoids were isolated and characterized. Their structural elucidation was achieved through an extensive analysis employing NMR, MS data, and DFT method. Notably, all compounds shared as identical molecular formula. Compound 2 was identified as a derivative of compound 1, while compounds 3 and 4 exhibited an identical planar structure. Determination of the configurations of chiral centers in compounds 1 and 2 involved a comparative analysis between measured and calculated ECD spectra, along with the application of DP4+ probability analysis. Distinctly, the configurations of isomers 3 and 4 were established by scrutinizing proton chemical shifts based on the NOE correlation.
참고문헌 (12)
- S. Rajaram, , Bioorg. Med. Chem. Lett, 23, pp.6234~ (2013)
- T. Gyeltshen, , J. Nat. Prod, 86, pp.1584~ (2023)
- H. N. Kamel, , Pharm. Biol, 43, pp.243~ (2005)
- S. Y. Cheng, , J. Nat. Prod, 73, pp.771~ (2010)
- Su Young Park, "Three sterol sulfates isolated from a Marine Sponge Acanthodoryx fibrosa", Journal of the Korean Magnetic Resonance Society, 11(2), pp.122~128 (2007), 한국자기공명학회
- B. S. Hwang, , Molecules, 26, pp.3164~ (2021)
- J. Vaara, , Prog. Nucl. Magn. Reson. Spectrosc, 41, pp.233~ (2002)
- G. Pescitelli, , Chem. Soc. Rev, 40, pp.4603~ (2011)
- W. S. Brickell, , J. Chem. Soc. B, 691 (1971)
- W. Hehre, , J. Nat. Prod, 82, pp.2299~ (2019)
- N. Grimblat, , J. Org. Chem, 80, pp.12526~ (2015)
- A. Bagno, , Chem. Eur. J, 12, pp.5514~ (2006)