본문 바로가기
KERD
논문KCI 등재

천마의 용량에 따른 기억력 향상 효과에 대한 연구

The Verify of Memory Improvement by Gastrodia Elata Blume Depends on the Amount

0

조회

0

다운로드

4

인용

0

참고문헌

키워드

주제분류한의학

초록

Objectives: This study was designed to investigate the dose-dependent effects of Gastrodia elata Blume for memory improvement.Methods: This study was a 12-weeks, double blind, and comparative clinical study. Those who were eli-gible worked with a group of healthy seniors, all 60 years of age or older. 22 subjects were randomized either to Gastrodia elata Blume powder form that was steeped in hot water or placebo. We measured the faculty of memory by using MMSE-K, Digit Span, Letter Fluency Test, Word List Memory Test, and Trail Making Test, and again after 12 weeks. Results: 1) Neither Gastrodia elata Blume groups nor control have a difference in MMSE-K, Digit Span, Letter Fluency Test, and Trail Making Test. 2) Gastrodia elata Blume group showed significant advances in immediate recall 1 and 2 of Word List Memory Test, and 3 g group show better results than the 4 g group. 3) 4 g Gastrodia elata Blume group showed significant advances in the recognition of Word List Memory Test. Conclusions: The results suggest that positive effects on memory improvement due to Gastrodia elata Blume depend on the amount.

Abstract

Objectives: This study was designed to investigate the dose-dependent effects of Gastrodia elata Blume for memory improvement.Methods: This study was a 12-weeks, double blind, and comparative clinical study. Those who were eli-gible worked with a group of healthy seniors, all 60 years of age or older. 22 subjects were randomized either to Gastrodia elata Blume powder form that was steeped in hot water or placebo. We measured the faculty of memory by using MMSE-K, Digit Span, Letter Fluency Test, Word List Memory Test, and Trail Making Test, and again after 12 weeks. Results: 1) Neither Gastrodia elata Blume groups nor control have a difference in MMSE-K, Digit Span, Letter Fluency Test, and Trail Making Test. 2) Gastrodia elata Blume group showed significant advances in immediate recall 1 and 2 of Word List Memory Test, and 3 g group show better results than the 4 g group. 3) 4 g Gastrodia elata Blume group showed significant advances in the recognition of Word List Memory Test. Conclusions: The results suggest that positive effects on memory improvement due to Gastrodia elata Blume depend on the amount.

참고문헌 (25)

  1. National Statistical Office, "Estimated future population", ~ (2011)
  2. Nationalwide study on the prevalence of dementia in Korean elders, "Maengje Cho", Ministry for Health, Welfare and Family Affairs, ~ (2008)
  3. Korean Dementia Association, "Dementia A Clinical Approach", pp.23~392 (2006), Academia
  4. College of Oriental medicine Neuropsychiatry textbook Compilation Committee, "The Oriental Neuropsychiatry", pp.325~326, Jipmoondang
  5. Hwang WW, "The Oriental Psychiatric Medicine", pp.605~ (1989), Modern medicine publisher
  6. Kim CM, "A complete translation Encyclopedia of Chinese herbal medicine", pp.4105~4107 (1999), Jungdam
  7. Kim JH, "Effect of Scutellaria Baicalensis and astrodia elata on Learning and Memory Processes", The Journals of the Korean Oriental Medical Society, 23(2), pp.134~135 (2002)
  8. Heo J., "Donguibogam", pp.2183~ (2006), The Society of Hyungsang Medicine Donguibogam publisher
  9. Jiang KM, "Kyojeong Banjedaesajeon" (1991), Euisungdang
  10. Choe JY, "K-DRS Korean edition professional outline", pp.7~37 (1998), Hakjisa
  11. Folstein, M. F., ""Minimental state" : a practical method for grading the cognitive state of patients for clinician", J Psychiaty Res, 12, pp.189~198 (1975)
  12. Kwon YC, "Standardization of Korean of the Mini-Mental State Examination (MMSE-K) for Use in the Elderly. Part II. Diagnostic Validity", Psychiatry investigation, 28(1), pp.125~135 (1989)
  13. Kim HG, "Cognition Scale for Older Adults manual" (2007), Neuropsy
  14. Spreen, F. O., "Manual of instructions for the Neurosensory Center Comprehensive Examination for Aphasia" (1977), University of Victoria
  15. Kang YW, "Brief Report : A normative study of the Korean version of Controlled Oral Word Association Test ( COWAT ) in the elderly", Korean Journal of Clinical Psychology, 19(2), pp.385~392 (2000)
  16. Woo JI, "The Korean version of the Consortium to Establish a Registry for Alzheimer's Disease(CERAD-K)" (2003), Seoul National University publishing department
  17. Lee KH, "The effect of Children's Field Independence-Dependence Cognitive style and Executive Function on recall", master, pp.2008
  18. Lee CY, "The Effects of Cognitive-Behavioral Gameplay Program on the Executive Function of Young Children with Mild ADHD Symptoms", master, pp.2011
  19. Lee GG, "Department of Neurology, College of Medicine, Seoul National University. Neuroscience", pp.19~20 (2005), Beommun publisher
  20. Academy of Asian studies, "The oriental internal medicine", pp.179~181 (1994), Yeogang publisher
  21. Yoo HY., "The Oriental Psychiatry", pp.57~ (1988), Namsandang
  22. 정영수, "癡呆病態모델에서 天麻의 神經細胞 損傷 保護效果", 동의신경정신과학회지, 21(2), pp.125~140 (2010), 대한한방신경정신과학회
  23. 윤유석, "천마가 중대뇌동맥 폐쇄 흰쥐의 신경세포 자연사에 미치는 영향", 한방재활의학과학회지, 19(3), pp.1~13 (2009), 한방재활의학과학회
  24. 문상관, "천마추출물이 정상인의 뇌혈류에 미치는 영향", 대한한의학회지, 26(1), pp.115~122 (2005), 대한한의학회
  25. Lezak, M.D., "Neuropsychological assessment", pp.371~374 (2004), Oxford University Press

관련 논문AI추천

천마를 이용한 기억력 향상 효과 연구김경옥, 김우철, 김정상, 정종길대한한방신경정신과학회 · 동의신경정신과학회지2013 · 제24권 제1호Effects of the Combination Herbal Extract on Working Memory and White Matter Integrity in Healthy Individuals with Subjective Memory Complaints : A Randomized, Double-Blind, Placebo-Controlled Clinical Trial강일향, 권오란, 김경희, 김주희, 반순현, 윤수정, 이두석, 이상곤, 이선혜, 이선호, 이은희, 임수미, 임주연대한생물정신의학회 · 생물정신의학2015 · 제22권 제2호LPS에 의해 유도된 인지기능 손상모델에 대한 천마 추출물의 방어효과강형원, 권강범, 김예슬, 김하림, 류도곤, 박은희대한한방신경정신과학회 · 동의신경정신과학회지2022 · 제33권 제3호Scopolamine 유발 기억장애 모델에서천마 추출물의 기억력 개선 효과권강범, 김려원, 김창수, 윤철환, 이은숙, 최한별, 한상윤한의병리학회 · 동의생리병리학회지2025 · 제39권 제6호치매의 한약물 치료에 대한 체계적 임상논문 고찰 - 국내문헌을 중심으로 -권용주, 조성훈, 조혜영, 황의완대한한방신경정신과학회 · 동의신경정신과학회지2010 · 제21권 제4호癡呆病態모델에서 天麻의 神經細胞 損傷 保護效果강재현, 구병수, 권영미, 김근우, 박세환, 정영수대한한방신경정신과학회 · 동의신경정신과학회지2010 · 제21권 제2호

이 간행물의 다른 논문 (8건)