본문 바로가기
KERD
논문KCI 등재

Blood Glucose Monitoring and Communicative Implantable Chip Using a Wireless Power Transfer

0

조회

0

다운로드

0

인용

0

참고문헌

키워드

초록

This work proposes a wireless operating system for continuous monitoring of glucose level. The system consists of an implantable device and an external readout transmitter. The implantable device measures a glucose level and wirelessly communicates with the external reader, employing the backscattered modulation for low-power operation. The implantable device converts the light intensity scattered from a fluorescent hydrogel sensor reacting on glucose level to the frequency-modulated signal, and sends this back to the external reader while it is being powered wirelessly. The entire implantable device including the 1000×600-μm^2 die fabricated in TSMC 180-nm CMOS process is bonded on PCB and the fluorescence hydrogel sensor fits in 2×2.5 mm2, and consumes 146.5 μW of power in average during the operation.

Abstract

This work proposes a wireless operating system for continuous monitoring of glucose level. The system consists of an implantable device and an external readout transmitter. The implantable device measures a glucose level and wirelessly communicates with the external reader, employing the backscattered modulation for low-power operation. The implantable device converts the light intensity scattered from a fluorescent hydrogel sensor reacting on glucose level to the frequency-modulated signal, and sends this back to the external reader while it is being powered wirelessly. The entire implantable device including the 1000×600-μm^2 die fabricated in TSMC 180-nm CMOS process is bonded on PCB and the fluorescence hydrogel sensor fits in 2×2.5 mm2, and consumes 146.5 μW of power in average during the operation.

참고문헌 (16)

  1. Liao, Y.T., "A 3-uW CMOS Glucose Sensor for Wireless Contact-Lens Tear Glucose Monitoring", IEEE J.-Solid-State Circuits, 47, pp.335~344 (2011)
  2. Mok, J.W., "Wireless smart contact lens for diabetic diagnosis and therapy", Sci. Adv, 6, pp.eaba3252~ (2020)
  3. Koh, A., "A soft, wearable microfluidic device for the capture, storage, and colorimetric sensing of sweat", Sci. Transl. Med, 8, pp.366ra165~ (2016)
  4. Haider, M.R., "Low-power low-voltage current readout circuit for inductively powered implant system", IEEE Trans. Biomed. Circuits Syst, 4, pp.205~213 (2010)
  5. Mujeeb-U-Rahman, M., "A Novel Needle-Injectable Millimeter scale Wireless Electrochemical Glucose Sensing Platform for Artificial Pancreas Applications", Sci. Rep, 9, pp.1~11 (2019)
  6. Hassan, R.S., "A minimally invasive implantable sensor for continuous wireless glucose monitoring based on a passive resonator", IEEE Antennas Wirel. Propag. Lett, 19, pp.124~128 (2019)
  7. "Update on our Smart Lens program with Alcon" (2018)[URL]
  8. H. Lee, "Batteryless, miniaturized implantable glucose sensor using a fluorescent hydrogel", Sensors, 21(24), pp.8464~ (2021)
  9. Y. J. Heo, "Long-term in vivo glucose monitoring using fluorescent hydrogel fibers", Proceedings of the National Academy of Sciences, 108(33), pp.13 399~13 403 (2011)
  10. A. DeHennis, "An nfc-enabled cmos ic for a wireless fully implantable glucose sensor", IEEE journal of biomedical and health informatics, 20(1), pp.18~28 (2015)
  11. A. S. Y. Poon, "Optimal Frequency for Wireless Power Transmission Into Dispersive Tissue", IEEE Transactions on Antennas and Propagation, 58(5), pp.1739~1750 (2010)
  12. S. Kim, "Midfield Wireless Powering of Subwavelength Autonomous Devices", Physical Review Letters, 110(20) (2013)
  13. K. Kotani, "High-Efficiency Differential-Drive CMOS Rectifier for UHF RFIDs", IEEE Journal of Solid-State Circuits, 44(11), pp.3011~3018 (2009)
  14. Razavi, Behzad, "Design of Analog Cmos Integrated Circuits" (2001), McGraw-Hill
  15. Graeme, J.G., "Photodiode Amplifiers: OP AMP Solutions. Gain technology" (2020), McGraw-Hill Education
  16. Razavi, B., "Principles of data conversion system design" (1995), IEEE Press

관련 논문AI추천

이 간행물의 다른 논문 (7건)